Antibacterial Activity Test Combination of Kencur (Kaempferia galanga L) Rhizome and Sapodilla (Manilkara zapota L) Leaf Extract against Escherichia coli

  • Amanda Fadilah Ilhani Poltekkes Kemenkes Medan
  • Ismedsyah Ismedsyah Poltekkes Kemenkes Medan
Keywords: Antibacterial, Kencur, Sapodilla, Escherichia coli

Abstract

Kencur (Kaempferia galanga L) rhizome and sapodilla (Manilkara zapota L) leaf are one of the plants that have been empirically proven to treat infections. Kencur rhizome contains chemical compounds such as saponins, polyphenols, flavonoids, and essential oil. Sapodilla leaf contains chemical compounds such as saponins, tannins, and flavonoids which function as antibacterial. The aim of this study was to determine the antibacterial activity of ethanol extract of kencur rhizome and sapodilla leaf ethanol extract combination against Escherichia coli bacteria. This study used an experimental method by looking at the antibacterial activity of ethanol extract of kencur rhizome and sapodilla leaf combination at a concentration ratio of 60%: 40%, 65%: 35%, 70%: 30%, 30 μg of chloramphenicol as a positive control and 70 % of alcohol as negative control. The study result showed that the combination of ethanol extract of Kencur rhizome and sapodilla leaf compared to 60%: 40%, 65%: 35% and 70%: 30%, each had an inhibitory zone against Escherichia coli of 15 mm, 13.17 mm, and 14.17 mm, chloramphenicol has an inhibitory zone of 19.83 mm and 70% alcohol does not have an inhibitory zone. This study concludes that the combination of Ethanol Extracts of Kencur Rhizome (Kaempferia galanga L) and Sapodilla leaf (Manilkara zapota L) which inhibited the growth of Escherichia coli and were more effective at a 60%: 40% comparison concentration because they were in the range of 14-16 based on Indonesian pharmacopeia standard of IV edition.

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Author Biographies

Amanda Fadilah Ilhani, Poltekkes Kemenkes Medan

Student of Pharmacy

Poltekkes Kemenkes Medan

Ismedsyah Ismedsyah, Poltekkes Kemenkes Medan

Senior Lecturer of Pharmacy

Poltekkes Kemenkes Medan

References

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Published
2018-10-09
How to Cite
Ilhani, A. F., & Ismedsyah, I. (2018). Antibacterial Activity Test Combination of Kencur (Kaempferia galanga L) Rhizome and Sapodilla (Manilkara zapota L) Leaf Extract against Escherichia coli. Borneo Journal of Pharmacy, 1(2), 77-80. Retrieved from http://journal.umpalangkaraya.ac.id/index.php/bjop/article/view/368
Section
Natural Product Development