Antibacterial Activity Test of Ethanol Extract Pineapple (Ananas comosus (L.) Merr.) Peel against Growth of Propionibacterium acnes
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Submitted
26 August 2019
Published
30 November 2019
Keywords:
-
pineapple peel extract, antibacterial, Propionibacterium acnes
Abstract
Pineapple peel (Ananas comosus (L.) Merr.) is waste from the pineapple fruit. The purpose of this study was to determine the content of pineapple peel extract and to antibacterial activity in various concentrations effective in inhibiting the growth of Propionibacterium acnes. The pineapple peel extract is made by using the extraction method in the form of maceration. The method used in the inhibitory test using the three replication samples in each treatment group. The sample consisted of 10 treatment groups ie pineapple peel extract concentration 12.5%, 25%, 37.5%, 50%, 62.5%, 75%, 87.5%, and 100%, as well as positive and negative control. The results obtained from pineapple peel screening contain flavonoid and saponin compounds. The data analysis shows that pineapple peel extract concentrations of 50%, 62.5%, 75%, 87.5%, and 100% had inhibitory zones with the medium-strong category while clindamycin as the control has a strong inhibition zone. The conclusion of this research proves that pineapple peel extract has antibacterial power to P. acnes with effective concentration is 100% with the strong category.
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References
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Ventola, C.L. 2015. The Antibiotic Resistance Crisis. Part 1: Causes and Threats. Pharmacy and Therapeutics. 40(4):277-283.
Yeragamreddy, P.R., Peraman, R., Routhu, H., Babu, N. 2013. In Vitro Antitubercular and Antibacterial Activities of Isolated Constituents and Column Fractions from Leaves of Cassia occidentalis, Camellia sinensis and Ananas comosus. African Journal of Pharmacology and Therapeutics. 2(4):116-123.
Bergler-Czop, B., Brzezińska-Wcisło, L. 2013. Dermatological problems of the puberty. Advances in Dermatology and Allergology. 30(3):178-187. https://dx.doi.org/10.5114/pdia.2013.35621
Damogalad, V., Edy, H.J., Supriati, H.S. 2013. Formulasi Krim Tabir Surya Ekstrak Kulit Nanas (Ananas comosus L Merr) dan Uji In Vitro Nilai Sun Protecting Factor (SPF). Pharmacon. 2(2):39-44.
Daud, N.S., Akbar, A.J., Nurhikma, E., Karmilah, K. 2018. Formulation of Snail Slime (Achatina Fulica) Anti-Acne Emulgel using Tween 80-Span 80 as Emulsifying and HPMC as Gelling Agent. Borneo Journal of Pharmacy. 1(2):64-67. https://doi.org/10.33084/bjop.v1i2.369
Debalke, D. Birhan, M., Kinubeh, A., Yayeh, M. 2018. Assessments of Antibacterial Effects of Aqueous-Ethanolic Extracts of Sida rhombifolia's Aerial Part. The Scientific World Journal. 2018:8429809. https://dx.doi.org/10.1155/2018/8429809
Deng, G.F., Shen, C., Xu, X.R., Kuang, R.D., Guo, Y.J., Zeng, L.S., Gao, L.L., Lin, X., Xie, J.F., Xia, E.Q., Li, S., Wu, S., Chen, F., Ling, W.H., Li, H.B. 2012. Potential of Fruit Wastes as Natural Resources of Bioactive Compounds. International Journal of Molecular Sciences. 13(7):8308-8323. https://dx.doi.org/10.3390/ijms13078308
Echeverria, J., Opazo, J., Mendoza, L., Urzua, A., Wilkens, M. 2017. Structure-Activity and Lipophilicity Relationships of Selected Antibacterial Natural Flavones and Flavanones of Chilean Flora. Molecules. 22(4):608. https://dx.doi.org/10.3390/molecules22040608
Fox, L., Csongradi, C., Aucamp, M., du Plessis, J., Gerber, M. 2016. Treatment Modalities for Acne. Molecules. 21(8):1063. https://dx.doi.org/10.3390/molecules21081063
Lely, N., Firdiawan, A., Martha, S. 2016. Efektivitas Antibakteri Minyak Atsiri Rimpang Jahe Merah (Zingiber officinale var. Rubrum) Terhadap Bakteri Jerawat. Scientia: Jurnal Farmasi dan Kesehatan. 6(1):44-49. http://dx.doi.org/10.36434/scientia.v6i1.41
Lynn, D.D., Umari, T., Dunnick, C.A., Dellavalle, R.P. 2016. The epidemiology of acne vulgaris in late adolescence. Adolescent Health, Medicine and Therapeutics. 7:13-25. https://dx.doi.org/10.2147/AHMT.S55832
Mandal, S., Patra, A., Samanta, A., Roy, S., Mandal, A., Mahapatra, T.D., Pradhan, S., Das, K., Nandi, D.K. 2013. Analysis of phytochemical profile of Terminalia arjuna bark extract with antioxidative and antimicrobial properties. Asian Pacific Journal of Tropical Biomedicine. 3(12):960-966. https://dx.doi.org/10.1016/S2221-1691(13)60186-0
McLaughin, J., Watterson, S., Layton, A.M., Bjourson, A.J., Barnard, E., McDowell, A. 2019. Propionibacterium acnes and Acne Vulgaris: New Insights from the Integration of Population Genetic, Multi-Omic, Biochemical and Host-Microbe Studies. Microorganisms. 7(5):128. https://dx.doi.org/10.3390/microorganisms7050128
Mir, M.A., Parihar, K., Tabasum, U., Kumari, E. 2016. Estimation of alkaloid, saponin and flavonoid, content in various extracts of Crocus sativa. Journal of Medicinal Plants Studies. 4(5):171-174.
Ngibad, K. 2019. Phytochemical Screening of Sunflower Leaf (Helianthus annuus) and Anting-Anting (Acalypha indica Linn) Plant Ethanol Extract. Borneo Journal of Pharmacy. 2(1):24-30. https://doi.org/10.33084/bjop.v2i1.689
Nurhasnawati, H., Sundu, R., Sapri, Supriningrum, R., Kuspradini, H., Arung, E.T. 2019. Antioxidant activity, total phenolic and flavonoid content of several indigenous species of ferns in East Kalimantan, Indonesia. Biodiversitas. 20(2):576-580. https://doi.org/10.13057/biodiv/d200238
Nuria, M.C., Faizatun, A., Sumantri. 2009. Uji Aktivitas Antibakteri Ekstrak Etanol Daun Jarak Pagar (Jatropha curcas L) terhadap Bakteri Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, dan Salmonella typhi ATCC 1408. Mediagro: Jurnal Ilmu-Ilmu Pertanian. 5(2):26-37.
Osonga, F.J., Akgul, A., Miller, R.M., Eshun, G.B., Yazgan, I., Akgul, A., Sadik, O.A. 2019. Antimicrobial Activity of a New Class of Phosphorylated and Modified Flavonoids. ACS Omega. 4(7):12865-12871. https://dx.doi.org/10.1021/acsomega.9b00077
Putri, R.M.A., Yuanita, T., Roelianto, M. 2016. Daya Anti Bakteri Ekstrak Kulit Nanas (Ananas comosus) terhadap Pertumbuhan Bakteri Enterococcus Faecalis. Conservative Dentistry Journal. 6(2):1-6.
Sanders, E.R. 2012. Aseptic Laboratory Techniques: Plating Methods. Journal of Visualized Experiments. 63:3064. https://dx.doi.org/10.3791/3064
Sinha, P., Srivastava, S., Mishra, N., Yadav, N.P. 2014. New Perspectives on Antiacne Plant Drugs: Contribution to Modern Therapeutics. BioMed Research International. 2014:301304. https://dx.doi.org/10.1155/2014/301304
Ventola, C.L. 2015. The Antibiotic Resistance Crisis. Part 1: Causes and Threats. Pharmacy and Therapeutics. 40(4):277-283.
Yeragamreddy, P.R., Peraman, R., Routhu, H., Babu, N. 2013. In Vitro Antitubercular and Antibacterial Activities of Isolated Constituents and Column Fractions from Leaves of Cassia occidentalis, Camellia sinensis and Ananas comosus. African Journal of Pharmacology and Therapeutics. 2(4):116-123.
Authors
1.
Fitriyanti F, Hendrawan MNR, Astuti KI. Antibacterial Activity Test of Ethanol Extract Pineapple (Ananas comosus (L.) Merr.) Peel against Growth of Propionibacterium acnes. Borneo J Pharm [Internet]. 2019Nov.30 [cited 2024Apr.24];2(2):108-13. Available from: https://journal.umpr.ac.id/index.php/bjop/article/view/928
Copyright (c) 2019 Fitriyanti Fitriyanti, Muhammad Nur Rahman Hendrawan, Karunita Ika Astuti
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