2024-03-29T06:26:49Z
https://journal.umpr.ac.id/index.php/bjop/oai
oai:journal.umpr.ac.id:article/175
2019-11-21T05:47:06Z
bjop:Clin-Comm-Pharm
Pengaruh Penggunaan Media Video Pembelajaran terhadap Pemahaman tentang Komunikasi dan Konseling Obat pada Mahasiswa S1 Farmasi: Influence of Use Video Learning Media on Understanding of Communications and Counseling Medicine in Undergraduate Students Pharmacy
Mardiati, Nurul
Restapaty, Ratna
Learning media
Video learning
Communication
Drug counseling
Community Pharmacy
Teaching-learning activities by lecturers are expected can use creative learning media with the use of appropriate media for the concepts to be conveyed to achieve the desired educational goals. Learning media is a tool used by lecturers to facilitate the delivery of learning materials. Learning media that can be used alone vary widely, one of which is learning video. This study aims to determine the influence of the use of video learning media on the understanding of communication and counseling drug on undergraduate students Pharmacy High School of Health Sciences Borneo Lestari Semester V Academic Year 2016/2017. This research is using the experimental method. The research design used was The Randomized Control-Group Pretest-Posttest Control Group Design. In this design, there are two groups that first randomly selected one class for the experimental group (using learning video) and one class for the control group (not using instructional video media). Sign value based on Wilcoxon test shows 0,025 <0,05. This indicates that there is the influence of t use of video learning media on the understanding of communication and counseling drug on undergraduate students Pharmacy High School of Health Sciences Borneo Lestari Semester V Academic Year 2016/2017.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-05-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/175
10.33084/bjop.v1i1.175
Borneo Journal of Pharmacy; Vol. 1 No. 1 (2018): Borneo Journal of Pharmacy; 37-40
2621-4814
10.33084/bjop.v1i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/175/234
Copyright (c) 2018 Nurul Mardiati, Ratna Restapaty
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/235
2019-12-01T11:54:39Z
bjop:Pharm-Phyto
Inventarisasi Tumbuhan Obat di Desa Pelangsian Kecamatan Mentawa Baru Ketapang Kabupaten Kotawaringin Timur: Inventory of Medicinal Plant in Pelangsian Village Mentawa Baru Ketapang Subdistrict Regency of East Kotawaringin
Qamariah, Nurul
Mulyani, Evi
Dewi, Nurmila
Inventory
Medicinal Plant
Pelangsian Village
Pharmacognosy
Indonesia is a large archipelagic country and it is a tropical country with a huge variety of plants. Borneo as one of five major islands has tropical rainforest with a high level of plants diversities in the world. Traditional treatment by medicinal plants is still used by the people in Pelangsian village. The purpose of this study was to find out how the way the people in Pelangsian village use the traditional medicines, also about the type and the benefits of medical plants there, and which parts of the plants that used to be the traditional medicines. This research uses the descriptive method with a qualitative approach, data collecting is done by making an observation and interviews. Sampling in this research used purposive sampling technique in order to determine key informant with criteria that have been determined by the researcher and snowball sampling that determines the next informant who has already recommended by the key informant before. The result of the research was there are 52 species of medicinal plants that have been determined, the leaves, trunks, peels, fruit, seeds, roots, woods, rhizomes, are the parts of the plants that usually used by the people there and the way to use those herbs is boiled, stacked, rubbed and consumed directly.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-05-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/235
10.33084/bjop.v1i1.235
Borneo Journal of Pharmacy; Vol. 1 No. 1 (2018): Borneo Journal of Pharmacy; 1-10
2621-4814
10.33084/bjop.v1i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/235/227
Copyright (c) 2018 Nurul Qamariah, Evi Mulyani, Nurmila Dewi
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/236
2019-10-11T09:04:12Z
bjop:Nat-Pro-Dev
Uji Daya Hambat Ekstrak Etanol Daun Jerangau Hijau terhadap Staphylococcus aureus: The Inhibitory Test of Ethanolic Extract of Jerangau Hijau Leaves against Staphylococcus aureus
Novaryatiin, Susi
Pratomo, Guntur Satrio
Yunari, Cindia
The inhibitory test
Jerangau Hijau
Staphylococcus aureus
Microbiology
Jerangau Hijau is a medicinal plant believed by the people of Central Kalimantan to have an efficacy of treating fever, postpartum injuries, and anti-inflammatory. Based on previous research, Jerangau Hijau is known to contain chemical compounds namely flavonoids and saponins that have activity as an antibacterial. The purpose of this study was to find out whether the ethanolic extract of Jerangau Hijau leaves able to inhibit the growth of Staphylococcus aureus bacteria and to know the concentration of ethanolic extract of Jerangau Hijau leaves that able to inhibit the growth of Staphylococcus aureus bacteria. This research was conducted using the Kirby-Bauer method with disc paper. The extraction process was carried out by percolation method using 96% ethanol solvent. The results showed that the ethanolic extract of Jerangau Hijau leaves was able to inhibit the growth of Staphylococcus aureus bacteria, at concentrations of 1%, 5%, 10%, and 15% with mean inhibitory zones respectively 22±0.2 mm; 32.3±1.4 mm; 26.5±3.8 mm; and 13.1±3 mm.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-05-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/236
10.33084/bjop.v1i1.236
Borneo Journal of Pharmacy; Vol. 1 No. 1 (2018): Borneo Journal of Pharmacy; 11-15
2621-4814
10.33084/bjop.v1i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/236/228
Copyright (c) 2018 Susi Novaryatiin, Guntur Satrio Pratomo, Cindia Yunari
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/237
2019-10-11T09:04:09Z
bjop:Nat-Pro-Dev
Uji Daya Hambat Ekstrak Etanol Batang Saluang Belum terhadap Bakteri Escherichia coli: The Inhibitory Test of Ethanol Extract Saluang Belum Stem to Escherichia coli
Handayani, Rezqi
Qamariah, Nurul
Mardova, Saftaria Ayu
Saluang Belum
The Inhibitory Test
Escherichia coli
Microbiology
Saluang Belum one of the herbal plants that have the benefits as a traditional medicine in Central Kalimantan. People in Central Kalimantan trusted Saluang Belum stem has an empirical benefit as a stamina enhancing agent and as an antioxidant. From previous research, Saluang Belum stem has a secondary metabolite that was saponin and tannin. Of these two secondary metabolites scientifically have pharmacological effects one of which was able to inhibit bacterial growth. To prove it in this research, the inhibitory test of ethanol extract of Saluang Belum stem from the growth of Escherichia coli bacteria. The inhibitory test method used in this study was the diffusion method using a variety of concentrations of 0.5%, 1%, 5%, 10%, and 15%. The result of this research, that there was no inhibition zone on the media used in all concentration. From these results can be concluded Saluang Belum stem ethanol extract unable to inhibit the growth of E. coli bacteria at concentrations of 0.5%, 1%, 5%, 10%, and 15%.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-05-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/237
10.33084/bjop.v1i1.237
Borneo Journal of Pharmacy; Vol. 1 No. 1 (2018): Borneo Journal of Pharmacy; 16-18
2621-4814
10.33084/bjop.v1i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/237/229
Copyright (c) 2018 Rezqi Handayani, Nurul Qamariah, Saftaria Ayu Mardova
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/238
2019-11-24T02:52:41Z
bjop:Clin-Comm-Pharm
Kualitas Hidup Pasien Gagal Ginjal Kronis yang menjalani Hemodialisis di RSUD Dr. Doris Sylvanus Palangka Raya: Quality of Life of Chronic Kidney Disease Patients on Hemodialysis at Dr. Doris Sylvanus Hospital Palangka Raya
Mulia, Dewi Sari
Mulyani, Evi
Pratomo, Guntur Satrio
Chusna, Nurul
Chronic Kidney Diseases
Hemodialysis
Quality of Life
Community Pharmacy
Kidney disease includes various diseases and disorders affecting the kidney function. If not treated immediately then there will be kidney failure. Patients with Chronic Kidney Disease (CKD) require hemodialysis due to impaired endocrine, metabolic, electrolyte and acid-base functions. Hemodialysis is a substitute for kidney function to remove the rest of the metabolism. These hemodialysis actions can affect the quality of life of patients. The purpose of this study was to determine the quality of life of CKG patients undergoing hemodialysis therapy in dr. Doris Sylvanus Hospital Palangka Raya. This research uses the univariate quantitative method with a descriptive approach. Data were collected using a questionnaire adapted from the World Health Organization Quality of Life (WHOQoL)-BREF containing 26 items of questions covering four dimensions: physical, psychological, environmental and social. The sample used in this study as many as 30 people. Based on the assessment of the quality of life in this study showed that physical and psychological dimensions including in moderate quality of life, and environmental and social dimensions including a good quality of life.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-05-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/238
10.33084/bjop.v1i1.238
Borneo Journal of Pharmacy; Vol. 1 No. 1 (2018): Borneo Journal of Pharmacy; 19-21
2621-4814
10.33084/bjop.v1i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/238/230
Copyright (c) 2018 Dewi Sari Mulia, Evi Mulyani, Guntur Satrio Pratomo, Nurul Chusna
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/239
2019-11-25T15:30:47Z
bjop:Clin-Comm-Pharm
Tingkat Kepuasan Pasien terhadap Pelayanan Kefarmasian di RSUD Dr. Murjani Sampit: The Level of Patient Satisfaction to Pharmaceutical Service in Dr. Murjani Hospital Sampit
Novaryatiin, Susi
Ardhany, Syahrida Dian
Aliyah, Siti
Level of Satisfaction
Pharmaceutical Service
Dr. Murjani Hospital Sampit
Community Pharmacy
Good pharmaceutical services are directly oriented services in the drug use process aimed at ensuring the safety, effectiveness, and rationality of drug use by applying science and function in patient care. Consumer satisfaction is the response of customer or service user for each service provided. The purpose of this study was to determine the level of patient satisfaction with pharmaceutical service in RSUD Dr. Murjani Sampit. This study was conducted using the descriptive method. The level of satisfaction was measured by the five dimensions of service quality and was analyzed using percentage and Likert scale. The results showed the average percentage of interpretation score of 68% which means included in the category of satisfaction.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-05-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/239
10.33084/bjop.v1i1.239
Borneo Journal of Pharmacy; Vol. 1 No. 1 (2018): Borneo Journal of Pharmacy; 22-26
2621-4814
10.33084/bjop.v1i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/239/231
Copyright (c) 2018 Susi Novaryatiin, Syahrida Dian Ardhany, Siti Aliyah
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/240
2019-11-24T02:57:28Z
bjop:Clin-Comm-Pharm
Peningkatan Pengetahuan Ibu-Ibu Rumah Tangga Dalam Perilaku Pengobatan Sendiri Untuk Penatalaksanaan Demam Dengan Metode Cara Belajar Ibu Aktif: Increased Knowledge of Housewives in Self-Treatment Behavior for Fever Management Using Active Mother’s Ways of Learning Method
Handayani, Rezqi
Management of Fever
Self-medication
Active Mother’s Ways of Learning Method
Community Pharmacy
Pharmacological therapy in fever patients is to provide Antipyretic drugs, can be done by using a doctor's prescription or by self-treatment. The condition that occurs in the community is self-medication conducted in the category of irrational treatment therapy because it is not in accordance with the condition of the patient. So, it is necessary to do education using Active Mother’s Ways of Learning Method to the housewives about rational fever self-treatment. The sample in this study were 40 housewives in the Flamboyant Bawah, divided into two major groups namely the control and treatment groups. Each group was given a pretest and posttest in a questionnaire of fever management. In the treatment group, fever drug education given before posttest by used CBIA method. The results showed an increase in knowledge of housewives from before education and after education was seen from the acquisition of grades. The mean pretest value in the control group was 74.38 and the treatment group was 69.69. Statistical test results show there was no significant difference in the mean value between the control group and the treatment group. The mean posttest value in the control group was 77.81 and the treatment group was 87.50. There was a significant difference between the mean value of the control group and treatment group. From the results of the statistical analysis showed that the level of knowledge of the treatment group given education by used the CBIA method produced a higher value than the control group that was not given education.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-05-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/240
10.33084/bjop.v1i1.240
Borneo Journal of Pharmacy; Vol. 1 No. 1 (2018): Borneo Journal of Pharmacy; 27-30
2621-4814
10.33084/bjop.v1i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/240/232
Copyright (c) 2018 Rezqi Handayani
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/241
2019-12-01T14:44:04Z
bjop:Clin-Comm-Pharm
Tingkat Pengetahuan Siswi SMA Muhammadiyah Palangka Raya tentang Dysmenorrhea: Level of Knowledge of Female Students in Muhammadiyah Senior High School of Palangka Raya about Dysmenorrhea
Ardhany, Syahrida Dian
Dysmenorrhea
Female Student
Level of Knowledge
Community Pharmacy
Dysmenorrhea is one of the most common gynecological problems in women of all ages, the incidence of dysmenorrhea in the world is very large on average more than 50% of women in every world experience it. Muhammadiyah Senior High School is one of the best schools in Palangka Raya. Based on the observations that have been done by researcher the results are many students got dysmenorrhea with severe pain and certainly this condition will disrupt daily activity, especially when teaching and learning and so extracurricular activities. Therefore, research about the level of dysmenorrhea knowledge is needed. The research method was used in this research was a descriptive method with the technique of sampling purposive sampling with 10 statements questionnaire consist of 4 indicators there is the definition of dysmenorrhea, signs, and symptoms of dysmenorrhea, causes of dysmenorrhea and how to treat and prevent dysmenorrhea. Based on the results of the study was found that the level of dysmenorrhea knowledge female students Muhammadiyah Senior High School of Palangka Raya included in the sufficient category with percentage 66,67%, meanwhile based on knowledge indicators, definition of dysmenorrhea was 73.22% (sufficient category), signs and symptoms of dysmenorrhea was 58.93% (sufficient category), causes of dysmenorrhea was 63.69% (sufficient category) and how to treat and prevent dysmenorrhea was 68.75% (sufficient category). Based on the results of this study, it can be concluded that the level of dysmenorrhea knowledge female students Muhammadiyah Senior High School of Palangka Raya included in category sufficient to know with percentage 66.67%.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-05-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/241
10.33084/bjop.v1i1.241
Borneo Journal of Pharmacy; Vol. 1 No. 1 (2018): Borneo Journal of Pharmacy; 31-36
2621-4814
10.33084/bjop.v1i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/241/233
Copyright (c) 2018 Syahrida Dian Ardhany
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/242
2018-08-14T14:28:54Z
bjop:Editorial
oai:journal.umpr.ac.id:article/245
2019-11-25T15:34:40Z
bjop:Editorial
Cover, Content, and Editorial Note from Borneo J Pharm Vol. 1 No. 1 May 2018
Borneo J Pharm, Chief Editor of
Borneo Journal of Pharmacy
Assalamu’alaikum Wr. Wb. Alhamdulillahirabbil ‘alamin. After a long wait for almost 12 years from the first stand, finally, the scientific journal of the Department of Pharmacy Universitas Muhammadiyah Palangkaraya can be published. This scientific journal we named Borneo Journal of Pharmacy (Borneo J Pharm), inspired by the rich treasures of traditional medicine from the Borneo island which further became the basis for the development of this periodical scientific publication. Borneo J Pharm published every 6 months (2 issues/year) every May and November. The aim of this journal is to publish high-quality articles dedicated to all aspects of the latest outstanding developments in the field but not limited to Pharmacology-Toxicology, Pharmacognosy-Phytochemistry, Pharmaceutical, Analytical Pharmacy-Medicinal Chemistry, Natural Product Development, Clinical-Community Pharmacy, Management Pharmacy, and other Pharmacy aspects. It was first published online in May 2018 using Open Journal System (OJS) 3.1 platform with e-ISSN 2621-4814 by URL http://journal.umpalangkaraya.ac.id/index.php/bjop. This edition contains 12 articles consisting of Pharmacognosy-Phytochemistry, Natural Product Development, Clinical-Community Pharmacy, and Management Pharmacy topics. Editorial boards are fully aware that there is still room for improvement in this edition, hence with all humility willing to accept constructive suggestions and feedback for improvements to the publication for the next editions. We hope that all parties, especially the contributors of the articles, could participate in the success of the publication in the next edition in November 2018. Wassalamu’alaikum Wr. Wb.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-05-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Editorial Notes
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/245
10.33084/bjop.v1i1.245
Borneo Journal of Pharmacy; Vol. 1 No. 1 (2018): Borneo Journal of Pharmacy
2621-4814
10.33084/bjop.v1i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/245/2394
Copyright (c) 2018 Chief Editor of Borneo J Pharm
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/246
2019-11-25T15:43:17Z
bjop:Management
Profil Penggunaan Obat Antibiotik Golongan Penisilin di Apotek Rawat Jalan RSUD Kuala Kurun: Profile of Use of Penicillin Class of Antibiotic in Outpatient Pharmacy at Kuala Kurun Hospital
Chusna, Nurul
Pratomo, Guntur Satrio
Murwanda, Lisa
Kuala Kurun Hospital
Gunung Mas Regency
Penicillin Class of Antibiotic
Management Pharmacy
This study aims to determine the profile of the use of penicillin-class antibiotics in Kuala Kurun Hospital. The method used in this study is the descriptive method, the population in this study were all prescription outpatients that included penicillin group antibiotics at Kuala Kurun Hospital during the period of September-November 2015 totaling 132 prescriptions, all of which were used as samples. Data collection techniques used in the form of documentation is by calculating the use and classifying the antibiotic groups of penicillin based on the type of preparation. Based on the results of the study it was found that the most widely used antibiotic dosage forms in the period September-November 2015 were tablet preparations. The use of Amoxicillin tablets was prescribed for 92 prescriptions with 69.7% usage percentage. Ampicillin tablets are prescribed as many as 18 prescriptions with a usage percentage of 13.6%. Whereas antibiotics in the penicillin group, Amoxicillin syrup preparations total use as many as 22 recipes with a percentage of 16.7%. Based on the visit of patients who came to Kuala Kurun Hospital in the period of September-November 2015 there were 132 prescriptions of patients using penicillin class of antibiotics. After the data is grouped, it is known that the most widely used penicillin antibiotic form is a tablet preparation with Amoxicillin and Ampicillin.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-05-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/246
10.33084/bjop.v1i1.246
Borneo Journal of Pharmacy; Vol. 1 No. 1 (2018): Borneo Journal of Pharmacy; 41-43
2621-4814
10.33084/bjop.v1i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/246/237
Copyright (c) 2018 Nurul Chusna, Guntur Satrio Pratomo, Lisa Murwanda
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/247
2019-11-25T15:49:09Z
bjop:Management
Gambaran Penggunaan Obat Antidiare di 3 Puskesmas Kabupaten Barito Selatan: Description of The Use of Antidiarrheal in 3 South Barito District Health Centers
Chusna, Nurul
Mulyani, Evi
Asmadi, Ahmad
South Barito District Health Center
Antidiarrheal Drugs
Management Pharmacy
Diarrhea is a disease characterized by an increase in the frequency of defecation more than three times a day accompanied by changes in the shape and consistency of feces of patients. Bacterial, viral or parasitic infections can cause diarrhea. This study aimed to determine the profile of the use of antidiarrheal drugs for one semester in 3 South Barito District Health Centers namely Bangkuang Health Center, Sababilah Health Center, and Buntok Health Center. The results showed that there were differences in the use of drugs in each Health Center. Based on the type of drug that is most widely used, namely for the Bangkuang Health Center was Zink (1300 prescription), for Sababilah Health Center was Metronidazole (1350 prescription), and for Buntok Health Center was Cotrimoxazole (4650 prescriptions). Based on the age of patients aged 18-60 years for Bangkuang Health Center as many as 120 people, 279 people for Sababilah Health Center, and 315 people for Buntok Health Center. Based on male and female sex, for Bangkuang Health Center were 98 males and 167 females, for Sababilah Health Center were 233 males and 258 females, and for Buntok Health Center were 298 males and 398 females. Further research needed for a long time regarding the use of antidiarrheal drugs in other Health Centers.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-05-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/247
10.33084/bjop.v1i1.247
Borneo Journal of Pharmacy; Vol. 1 No. 1 (2018): Borneo Journal of Pharmacy; 44-46
2621-4814
10.33084/bjop.v1i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/247/238
Copyright (c) 2018 Nurul Chusna, Evi Mulyani, Ahmad Asmadi
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/248
2019-11-25T15:58:29Z
bjop:Management
Profil Penggunaan Obat Antihipertensi di RSUD Mas Amsyar Kasongan Kabupaten Katingan: A Profile of Antihypertensive Medicines in Mas Amsyar Hospital Kasongan Katingan Regency
Ardhany, Syahrida Dian
Pandaran, Wahyu
Pratama, Mohammad Rizki Fadhil
Amlodipine
Descriptive
Hypertension
Mas Amsyar Hospital
Management Pharmacy
Hypertension or high blood pressure is one of the lead causes of death. Hypertension can cause various complications with another disease, even the cause of heart disease, stroke, and kidney disorders. Hypertension is the second rank of the most diseases in Kabupaten Katingan. The purpose of this research is to know the profile of antihypertensive medicines in RSUD Mas Amsyar Kasongan. Method of this research was a descriptive method with saturation sampling used retrospective data on all prescription drugs in 2017. The results of this research based on the patient characteristic were found 43.3% men and 56.7% women, meanwhile 45.8% age < 45 years old and 54.2% for age > 45 years old. The antihypertensive drug items used are propranolol, telmisartan, amlodipine, lisinopril, furosemide, ramipril, valsartan, candesartan, irbesartan, and bisoprolol, meanwhile based on the classification of antihypertensive drugs. are angiotensin II receptor blockers (ARB), diuretics, angiotensin converting enzyme Inhibitors (ACEI), Calcium Channel Blockers (CCB) and alpha 2 adrenergic agonists. Based on the result, it can be concluded that hypertension patient in RSUD Mas Amsyar Kasongan is mostly female (56.7%) and age of hypertension patient is > 45 years old (54.2%). The most antihypertensive prescribed is monotherapy (72%) and the most item of the drug is amlodipine. (38%).
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-05-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/248
10.33084/bjop.v1i1.248
Borneo Journal of Pharmacy; Vol. 1 No. 1 (2018): Borneo Journal of Pharmacy; 47-50
2621-4814
10.33084/bjop.v1i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/248/239
Copyright (c) 2018 Syahrida Dian Ardhany, Wahyu Pandaran, Mohammad Rizki Fadhil Pratama
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/367
2019-11-25T16:24:59Z
bjop:Analytical-Medicinal
Profile of Thin-Layer Chromatography and UV-Vis Spectrophotometry of Akar Kuning Stem Extract (Arcangelisia flava)
Pratama, Mohammad Rizki Fadhil
Suratno, Suratno
Mulyani, Evi
TLC
UV-Vis Spectrophotometry
Akar Kuning
Pharmaceutical Analysis
This study aims to obtain the profile of Thin-Layer Chromatography (TLC) and Ultraviolet-Visible (UV-Vis) spectrophotometry from the ethanol extract of akar kuning stems (Arcangelisia flava) from Central Kalimantan. The TLC method is used with the orientation phase of the combination of polar-non-polar solvents resulting from orientation, while ethanol is used as the solvent for UV-Vis spectrophotometers. TLC results showed the formation of three stains on a mixture of polar solvents chloroform : methanol : water while in a non-polar solvent combination n-hexane : ethyl acetate did not show any stains. Comparison of retention factor (Rf) values shows the best combination of polar solvents to separate stains at a ratio of 5 : 2 : 1, respectively. Separation in 2-dimensional TLC with polar solvents showed a similar pattern with 1-dimensional separation in the form of three stains. UV-Vis spectrophotometer results showed four main peaks with wavelength 227.2; 267.4; 345.2; and 425.3 nm, respectively. The profile of the peak formed is very similar to that shown by berberine, one of the primary metabolites of akar kuning. TLC and UV-Vis spectrophotometers profiles obtained are expected to support further research using akar kuning stems, especially those from Central Kalimantan.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-11-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/367
10.33084/bjop.v1i2.367
Borneo Journal of Pharmacy; Vol. 1 No. 2 (2018): Borneo Journal of Pharmacy; 72-76
2621-4814
10.33084/bjop.v1i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/367/351
Copyright (c) 2018 Mohammad Rizki Fadhil Pratama, Suratno Suratno, Evi Mulyani
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/368
2019-12-01T13:46:09Z
bjop:Nat-Pro-Dev
RETRACTED: Antibacterial Activity Test Combination of Kencur (Kaempferia galanga L) Rhizome and Sapodilla (Manilkara zapota L) Leaf Extract against Escherichia coli
Ilhani, Amanda Fadilah
Ismedsyah, Ismedsyah
This article has been retracted as a result of multiple publications from the article by the relevant author
This article has been retracted as a result of multiple publications from the article by the relevant author. Similar articles can be found at the URL https://ejurnal.stmik-budidarma.ac.id/index.php/pelita/article/view/892
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-11-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/368
10.33084/bjop.v1i2.368
Borneo Journal of Pharmacy; Vol. 1 No. 2 (2018): Borneo Journal of Pharmacy; 77-80
2621-4814
10.33084/bjop.v1i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/368/827
Copyright (c) 2018 Amanda Fadilah Ilhani, Ismedsyah Ismedsyah
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/369
2019-12-01T12:11:39Z
bjop:Pharmaceut
Formulation of Snail Slime (Achatina Fulica) Anti-Acne Emulgel using Tween 80-Span 80 as Emulsifying and HPMC as Gelling Agent
Daud, Nur Saadah
Akbar, Achnis Jum
Nurhikma, Eny
Karmilah, Karmilah
Emulgel
Tween 80
Span 80
HPMC
Snail Slime
Formulation
Acne is the condition of abnormal skin which is indicated by inflammation caused by the bacterial infection of Propionibacterium acnes. The natural one which can be used for the medical treatment of acne is the snail mucus (Achatina fulica). The achasin protein of it has antibacterial activity. That snail mucus was made to the emulgel form. This research has used an experimental method and the emulgel formulation used the various concentration of emulsifying agents and the gelling agent. They were Tween 80 1.76%, 2.44%, 3.12%, Span 80 2.24%, 4.06%, 5.88% and HPMC 3.5%, 4.5%, 5.5%. Other additives were propylene glycol, Methylparaben, Propylparaben, paraffin liquid, menthol, and aquadest. Those formulations were tested in physical evaluation during 4 weeks of storage in room temperature, irritation test, hedonic test, and cycling test. The organoleptic test showed that the emulgel were the milk-white color with a distinctive smell. All emulgel were homogenous, non-irritant, with emulsion type oil in water (o/w). This emulgel also met the normal skin of pH value and spread ability’s range. The emulgel viscosity shift was < 10%, with the viscosity value inversely proportional to spreadability. Formula C with 3.12% of Tween 80, 5.88% of Span 80 and 5.5% of HPMC was claimed as the most stable formula both in room temperature and after cycling test. It was also the most preferred by the panelist.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-11-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/369
10.33084/bjop.v1i2.369
Borneo Journal of Pharmacy; Vol. 1 No. 2 (2018): Borneo Journal of Pharmacy; 64-67
2621-4814
10.33084/bjop.v1i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/369/353
Copyright (c) 2018 Nur Saadah Daud, Achnis Jum Akbar, Eny Nurhikma, Karmilah Karmilah
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/370
2019-12-01T13:54:50Z
bjop:Nat-Pro-Dev
Uji Aktivitas Antioksidan Ekstrak Etanol Buah dan Biji Buah Kalangkala (Litsea angulata) asal Kalimantan Selatan: Antioxidant Activity Test of Ethanolic Extract of Kalangkala (Litsea angulata) Fruits and Seeds from South Kalimantan
Saputri, Revita
Susiani, Eka Fitri
Antioxidant
Fruits
Seeds
Kalangkala
Litsea angulata
Phytochemistry
Free radicals are atoms or molecules, having one or more unpaired electrons. Increased production of free radicals can cause oxidative stress and cause many pathological conditions, e.g. cancers, heart diseases, and other diseases. The antioxidant can inhibit oxidative stress. Kalangkala (Litsea angulata) usually found in the South Kalimantan that can be used as an antioxidant. The study aimed to determine the antioxidant activity of ethanolic extract of Kalangkala fruits and seeds from South Kalimantan. Antioxidant activity was conducted qualitatively and quantitative uses the method DPPH. The result of the antioxidant activity of ethanolic extract of Kalangkala fruits and seeds qualitatively showed the presence of yellow spots on a purple background at Thin Layer Chromatography (TLC). The result of the activity of ethanolic extract of Kalangkala seeds quantitatively obtained IC50 value was 48.78 ppm and activity of ethanolic extract of Kalangkala fruits quantitatively obtained IC50 value was 243.14 ppm. Ethanolic extract of Kalangkala fruits and seeds from South Kalimantan has antioxidant activity.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-11-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/370
10.33084/bjop.v1i2.370
Borneo Journal of Pharmacy; Vol. 1 No. 2 (2018): Borneo Journal of Pharmacy; 81-84
2621-4814
10.33084/bjop.v1i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/370/354
Copyright (c) 2018 Revita Saputri, Eka Fitri Susiani
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/371
2019-12-01T12:06:02Z
bjop:Pharm-Tox
Effect of Giving Celecoxib on Uric Acid Level on Mice
Surya, Sara
Uric Acid
Celecoxib
non-steroidal anti-inflammatory
Pharmacology
Celecoxib is a breakthrough for pain relievers under the trade name Celebrex®, which is a Non-Steroid Anti-Inflammatory drug with its activity as an analgesic, antipyretic and anti-inflammatory. The purpose of this study was to find out the effect of celecoxib on blood uric acid levels of female white mice was induced with fresh cow liver extract. Experimental animals were divided into five groups, namely the control group (-), the control group (+) and the three dose groups, respectively 0.26, 0.52 and 1.04 mg/20 g. Observations were made on 7, 14 and 21 days with the Enzymatic Photometric method. The results showed that administration of celecoxib suspension at a dose of 0.26, 0.52 and 1.04 mg/20 g did not affect blood uric acid levels when compared with controls (P> 0.05).
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-11-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/371
10.33084/bjop.v1i2.371
Borneo Journal of Pharmacy; Vol. 1 No. 2 (2018): Borneo Journal of Pharmacy; 61-63
2621-4814
10.33084/bjop.v1i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/371/355
Copyright (c) 2018 Sara Surya
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/375
2019-12-01T13:33:37Z
bjop:Pharmaceut
Utilization of Catechins in Sunscreen Lotion Formulation
Kamal, Sefrianita
Rusdi, Mesa Sukmadani
Catechins
Gambir
Uncaria gambir Roxb
Lotion
Sunscreen
Technology
Skin is the outermost part of the body which is susceptible to solar radiation. Excessive radiation from ultraviolet (UV) rays can harm the skin, such as premature aging effect, erythema, and even skin cancer. Antioxidant compounds are needed to protect the skin from excessive exposure of UV rays. The antioxidant can be useful as a defense system against free radicals, ultraviolet radiation, and air pollution. One source of antioxidant from nature is Catechins. Catechins are obtained from the isolation of gambir (Uncaria gambir Roxb). Besides being useful as an antioxidant, Catechins also has antibacterial, antiseptic and wound healing effect. The antioxidant activity of Catechins can absorb UV rays, provides protection against oxidative stress, inflammation, and skin cancer. Therefore, the research is necessary to utilize the catechins in sunscreen lotion formulation. Catechins are isolated from gambir by maceration with hexane and ethyl acetate (polar, nonpolar and residual fractions). The fraction which yields the most catechins is used as the active substance in the formulation. The formulation is divided into 4 lotion formulas, namely Formula 1 with 0.5% catechins concentration, Formula 2 with 7.5% catechins concentration, Formula 3 with 1% catechins concentration, and Formula 4 without catechins substance. Physical stability test and effectiveness of sunscreen formulation are carried out on 4 lotion formulas. Physical stability tests included organoleptic observation, homogeneity, pH, and assessment of the effectiveness of sunscreen formulation by using UV-Vis Spectrophotometer.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-11-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/375
10.33084/bjop.v1i2.375
Borneo Journal of Pharmacy; Vol. 1 No. 2 (2018): Borneo Journal of Pharmacy; 68-71
2621-4814
10.33084/bjop.v1i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/375/360
Copyright (c) 2018 Sefrianita Kamal, Mesa Sukmadani Rusdi
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/379
2019-12-01T14:29:33Z
bjop:Clin-Comm-Pharm
Tingkat Kepuasan Pasien terhadap Pelayanan Kefarmasian di Puskesmas Pahandut Kota Palangka Raya: Level of Patient Satisfaction on Pharmaceutical Services in Community Health Centers of Pahandut Palangka Raya
Chusna, Nurul
Fetriana, Titra
Adawiyah, Rabiatul
Patient Satisfaction Level
Pharmaceutical Services
Pahandut Community Health Center
This study aims to determine the level of patient satisfaction with pharmaceutical services at the Pahandut Palangka Raya Community Health Center. This research method is descriptive. The sample in this study were 94 respondents, namely outpatients who received pharmacy services at the Pahandut Palangka Raya Community Health Center. The sampling technique in this study used a purposive sampling technique. The results of the study of patient satisfaction with pharmaceutical services based on the type of service obtained a score of 208 data located in the "very satisfied" area on the type of pharmacy staff responsiveness to patients, in the type of hospitality services pharmacy staff obtained a score of 206 data located "very satisfied", the types of clarity of pharmacy services in providing drug information obtained a score of 212 data located in "very satisfied" areas, in the type of drug service speed the score data 199 were found in "very satisfied" areas, in the types of medical services and medical devices the score data was obtained 200 lies in the "very satisfied" area, in the type of waiting room comfort service the 198 score data is located in the "very satisfied" area, and on the type of service the availability of brochures, leaflets, posters, as well as drug/health information is obtained score data 206 lies in the "very satisfied" area. The results of this study indicate that most patients were very satisfied with the pharmaceutical services provided by the Pahandut Community Health Center in Palangka Raya City.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-11-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/379
10.33084/bjop.v1i2.379
Borneo Journal of Pharmacy; Vol. 1 No. 2 (2018): Borneo Journal of Pharmacy; 89-92
2621-4814
10.33084/bjop.v1i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/379/361
Copyright (c) 2018 Nurul Chusna, Titra Fetriana, Rabiatul Adawiyah
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/400
2019-11-25T16:10:58Z
bjop:Management
Evaluasi Ketersediaan Obat Instalasi Farmasi Rumah Sakit Islam PKU Muhammadiyah Palangka Raya: Evaluation of the Availability of Medicines for the Pharmacy Installation of PKU Muhammadiyah Palangka Raya Islamic Hospital
Pratomo, Guntur Satrio
Umaternate, Agustinawati
Febriani, Tiara
Evaluation
PKU Muhammadiyah Islamic Hospital Palangka Raya
Drug Availability
Management Pharmacy
Health services quality is one manifestation of the demands of society in the current era of globalization so it must be carried out in accordance with the established code of ethics and health service standards, in order to provide satisfaction for each patient. In addition, this is very necessary because it is the right of every customer so that it can provide an opportunity for health service facilities to win the competition by providing other health services. The purpose of this study is to determine the level of availability of prescribed drugs for outpatient in pharmacy installation of PKU Muhammadiyah Islamic Hospital Palangka Raya in August to December 2017. This research is a non-experimental study using a descriptive method. Based on the results of the research conducted at the Pharmacy Installation of PKU Muhammadiyah Islamic Hospital Palangka Raya there were 4,956 prescription sheets with an average number of items of 3,035 prescribed drugs and 2,975 items of drugs submitted to obtain the average percentage of drug availability in the year 2017 is 98.02%. Based on the results of research conducted at the Pharmacy Installation of PKU Muhammadiyah Islamic Hospital Palangka Raya, it can be concluded from this study that the level of drug availability for outpatients of Pharmacy Installation at PKU Muhammadiyah Islamic Hospital Palangka Raya in August to December 2017 has shown well with an average percentage of drug availability of 98.02%.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-05-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/400
10.33084/bjop.v1i1.400
Borneo Journal of Pharmacy; Vol. 1 No. 1 (2018): Borneo Journal of Pharmacy; 51-55
2621-4814
10.33084/bjop.v1i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/400/378
Copyright (c) 2018 Guntur Satrio Pratomo, Agustinawati Umaternate, Tiara Febriani
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/427
2019-12-01T14:18:27Z
bjop:Nat-Pro-Dev
Antibacterial Activity of Ethanolic Extract of Sangkareho (Callicarpa longifolia Lam.) against Staphylococcus epidermidis
Novaryatiin, Susi
Sari, Asma'ul Ayuriska
Mulyani, Evi
Antibacterial Activity
Staphylococcus epidermidis
Sangkareho (Callicarpa longifolia Lam.)
Central Kalimantan
Microbiology
One of the plants believed as traditional medicine by the Dayak tribes in Central Kalimantan was Sangkareho (Callicarpa longifolia Lam.). This plant was usually used as traditional medicine by society in Puruk Cahu, Murung Raya Regency, Central Kalimantan and empirically believed could cure skin disease such as wound infection. This study was aimed to determine the antibacterial activity of ethanolic extract of Sangkareho (Callicarpa longifolia Lam). Antibacterial activity of ethanolic extract of Sangkareho was performed using disc diffusion technique, with four variations of concentration of 1%, 5%, 10%, and 15%. In this present study showed that ethanolic extract of Sangkareho has antibacterial activity against Staphylococcus epidermidis, wherein the resulting inhibition zone diameter was 7.3±0.8 mm, 8.3±1.2 mm, 10.5±0.5 mm, and 12.2±0.7 mm, respectively. Further research is needed to obtain an antibacterial activity of the fraction of Sangkareho.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-11-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/427
10.33084/bjop.v1i2.427
Borneo Journal of Pharmacy; Vol. 1 No. 2 (2018): Borneo Journal of Pharmacy; 85-88
2621-4814
10.33084/bjop.v1i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/427/389
Copyright (c) 2018 Susi Novaryatiin, Asma'ul Ayuriska Sari, Evi Mulyani
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/430
2022-04-01T20:17:05Z
bjop:Editorial
Cover, Content, and Editorial Note from Borneo J Pharm Vol. 1 No. 2 November 2018
Borneo J Pharm, Chief Editor of
Borneo Journal of Pharmacy
Alhamdulillahirabbil ‘alamin. The next edition of Borneo Journal of Pharmacy (Borneo J Pharm), has been published in November 2018. This journal aims to publish high-quality articles dedicated to all aspects of the latest outstanding developments in the field but not limited to Pharmacology-Toxicology, Pharmacognosy-Phytochemistry, Pharmaceutical, Analytical Pharmacy-Medicinal Chemistry, Natural Product Development, Clinical-Community Pharmacy, Management Pharmacy, and other Pharmacy aspects. It was first published online in May 2018 using Open Journal System (OJS) 3.1 platform with e-ISSN 2621-4814 by url http://journal.umpalangkaraya.ac.id/index.php/bjop. This edition contains eight articles consisting of Pharmacology-Toxicology, Pharmaceutical, Analytical Pharmacy-Medicinal Chemistry, Natural Product Development, and Clinical-Community Pharmacy topics. Editorial boards are fully aware that there is still room for improvement in this edition, hence with all humility willing to accept constructive suggestions and feedback for improvements to the publication for the next versions. The editorial board would like to thank the University, all editors and reviewers, and contributors of the scientific articles who have provided the repertoire in this issue. We hope that all parties, especially the contributors of the materials, could re-participate for the success of the publication in the next edition in May 2019.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2018-11-01
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Editorial Notes
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/430
10.33084/bjop.v1i2.430
Borneo Journal of Pharmacy; Vol. 1 No. 2 (2018): Borneo Journal of Pharmacy
2621-4814
10.33084/bjop.v1i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/430/2395
oai:journal.umpr.ac.id:article/571
2022-11-09T14:16:41Z
bjop:Management
Evaluation of Patient Satisfaction Towards Pharmacy Services at Hospital Outpatient Pharmacies in Padang
Surya, Sara
Kamal, Sefrianita
Putri, Lusia Eka
Satisfaction
Patients
Pharmacy Services
Outpatient Services
Hospitals in Padang
Evaluation
Patient satisfaction with the quality of pharmaceutical services is an essential indicator in the variety of health services in hospitals. Service quality is said to be enjoyable and satisfying if the services received are by or exceeding expectations. Otherwise, service quality is supposed to be inadequate or unsatisfactory if the service received is lower than expected. This study aims to determine the percentage level of patient satisfaction with pharmacy services at hospital outpatient pharmacies in Padang and to find out the pharmaceutical service system carried out by pharmacists on duty at hospital outpatient pharmacies that were located in Padang. This study used descriptive data collection. Satisfaction was assessed by giving questionnaires to respondents, and then the surveys were analyzed descriptively. Assessment of patient satisfaction was conducted by taking data through a poll of 100 respondents. Satisfaction analysis was carried out using a Likert scale, and then the data was displayed in the cartesian form.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-05-31
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/571
10.33084/bjop.v2i1.571
Borneo Journal of Pharmacy; Vol. 2 No. 1 (2019): Borneo Journal of Pharmacy; 31-34
2621-4814
10.33084/bjop.v2i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/571/668
Copyright (c) 2019 Sara Surya, Sefrianita Kamal, Lusia Eka Putri
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/689
2022-11-09T14:16:41Z
bjop:Nat-Pro-Dev
Phytochemical Screening of Sunflower Leaf (Helianthus annuus) and Anting-Anting (Acalypha indica Linn) Plant Ethanol Extract
Ngibad, Khoirul
Acalypha indica Linn
Helianthus annuus
ethanol
Phytochemical screening
Phytochemistry
Many local plants in Indonesia were used as traditional medicines, such as sunflower (Helianthus annuus) and anting-anting (Acalypha indica Linn) plants. Both of them can be used as an antimalarial, antibacterial, antifungal, analgesic, and antihyperlipidemic. This study aims to provide an overview of the secondary metabolites groups contained in sunflower leaf and anting-anting plants for the testing of alkaloids, flavonoids, tannins, saponins, steroids/triterpenoids, and sesquiterpenoids. This study included the extraction of sunflower leaves and anting-anting plants separately using the maceration method for 24 hours with 80% ethanol solvent. The stirring was aided by a shaker for three hours. Each extract was tested by phytochemicals with reagents. The results of phytochemical tests with reagents showed that 80% ethanol extract of sunflower leaves contained an alkaloid, tannin, steroid, and sesquiterpenoid compounds whereas anting-anting plants contained an alkaloid, flavonoid, and triterpenoid compounds.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-05-31
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/689
10.33084/bjop.v2i1.689
Borneo Journal of Pharmacy; Vol. 2 No. 1 (2019): Borneo Journal of Pharmacy; 24-30
2621-4814
10.33084/bjop.v2i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/689/667
Copyright (c) 2019 Khoirul Ngibad
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/694
2022-11-09T14:16:41Z
bjop:Pharm-Tox
Anti-inflammatory Activity of Pharmaceutical Gel of Ethanolic Extract from Marine Sponge Xestospongia Sp
Zubaydah, Wa Ode Sitti
Wahyuni, Wahyuni
Sahidin, Sahidin
Halik, Tian Amalia
Andriani, Rina
Indalifiany, Astrid
Fristiohady, Adryan
Gel
Ethanol extract
Xestospongia Sp. sponge
Carrageenan
Anti-inflammatory
Pharmacology
The aim of this study was to determine the characteristics of the gel formula based on it’s organoleptic properties, pH, viscosity, dispersion and homogenity by stability test carried out using the cycling test method and to determine the anti-inflammatory activity of the Xestospongia Sp. in male white mice (Mus musculus) by creating an artificial edema on the mice left foot induced by 1% λ-carrageenan. The gel formula from the ethanol extract of Xestospongia Sp. sponge was physically stable in terms of its organoleptic observation, homogenity, pH and viscosity test. However, the results that were obtained after dispersion test did not fulfill the requirements. In this study, the gel formula of the ethanol extract of Xestospongia Sp. sponge was administered on the mice left foot by using the variations in extract concentration of 0.02%, 0.03%, and 0.04%, and the gel without extract as a negative control and Galtaren®gel (1% Diclofenac Sodium) as a positive control. The evaluated data were in the form of mice leg edema volume measured based on its percent of inflammation and percent of inflammatory inhibition and observed for 360 minutes. The data were analyzed by using the Kruskal-Wallis test followed by the Mann-Whitney test with a confidence level of 95%. The results of this study showed that the gel formula of ethanol extract of Xestospongia Sp. sponge has an anti-inflammatory effect on each concentration and the formula that has a large anti-inflammatory effect was obtained at extract concentration of 0.04%.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-05-31
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/694
10.33084/bjop.v2i1.694
Borneo Journal of Pharmacy; Vol. 2 No. 1 (2019): Borneo Journal of Pharmacy; 1-9
2621-4814
10.33084/bjop.v2i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/694/663
Copyright (c) 2019 Wa Ode Sitti Zubaydah, Wahyuni Wahyuni, Sahidin Sahidin, Tian Amalia Halik, Rina Andriani, Astrid Indalifiany, Adryan Fristiohady
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/695
2022-11-09T14:16:41Z
bjop:Pharm-Phyto
Identification of Chemical Compounds from Karamunting Stem (Rhodomyrtus tomentosa) by Thin Layer Chromatography
Umaternate, Agustinawati
Chemical Compounds
Karamunting
TLC
Phytochemistry
Karamunting or Kalimantan Grapes (Rhodomyrtus tomentosa) is a medicinal plant from Central Kalimantan that is easily found in shrubs. Based on hereditary experiences of the people of Central Kalimantan, karamunting can be used for the treatment of various diseases, one of which is diabetes. This study aims to identify the chemical compounds contained in the karamunting stem. The method used is thin layer chromatography with eluent n-hexane : ethyl acetate and methanol : chloroform. Besides, a color reaction was carried out to determine the group of compounds contained in the methanol extract of the karamunting stem. The TLC results show better stain separation in eluent n-hexane : ethyl acetate with the formation of four stains. Positive results are indicated by the content of phenol, saponin, flavonoid and terpenoid compounds. The existence of this group of compounds can be a clue to further research on the truth of the efficacy of karamunting.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-05-31
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/695
10.33084/bjop.v2i1.695
Borneo Journal of Pharmacy; Vol. 2 No. 1 (2019): Borneo Journal of Pharmacy; 15-19
2621-4814
10.33084/bjop.v2i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/695/665
Copyright (c) 2019 Agustinawati Umaternate
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/707
2022-11-09T14:16:41Z
bjop:Pharm-Tox
Antidiarrheal Activity of Ethanolic Extract of Vernonia amygdalina Del Leaves againts Male Mice Induced by Oleum Ricini
Astuti, Karunita Ika
Wulandari, Lusiana Dwi
Susiani, Eka Fitri
Antidiarrheal
Oleum ricini
Vernonia amygdalina Del. leaves
Pharmacology
Leaves of Vernonia amygdalina Del. is one of the alternative plants that people use as antidiarrheal in Martapura, Banjar. The purpose of research to determine the antidiarrheal activity and the effectiveness of ethanolic extract of leaves against male mice. The negative control was given NaCMC 0.5% orally, positive control was given Loperamide HCl 0.005 mg/20 g orally, and groups of ethanolic extract of leaves were given dosages in 100 mg/kg BW, 200 mg/kg BW, and 400 mg/kg BW orally. After 1 hour of treatment, the groups were induced by Oleum ricini orally and were observed for 4 hours. Based on three parameters were frequency, weight, and consistency of diarrhea. From the results observation of that negative control, positive control, EEDA 100 mg/kg BW, 200 mg/kg BW, and 400 mg/kg BW for diarrhea frequency parameter was 7.4 ± 2.30; 2 ± 1.22; 5.8 ± 3.34; 6.2 ± 4.08; 2.4 ± 1.67; the weight parameter was 1.34 ± 0.43; 0.38 ± 0.29;0.66 ± 0.56; 0.57 ± 0.38; 0.49 ± 0.33 and then consistency of diarrhea with EEDA 400 mg/kg BW improved the consistency at 180 minutes compared to control group at 210 minutes. In conclusion, from all parameters of ethanolic extract of Vernonia amygdalina Del. leaves can give an antidiarrhea effect with optimum dosage is 400 mg/kg BW.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-05-31
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/707
10.33084/bjop.v2i1.707
Borneo Journal of Pharmacy; Vol. 2 No. 1 (2019): Borneo Journal of Pharmacy; 10-14
2621-4814
10.33084/bjop.v2i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/707/664
Copyright (c) 2019 Karunita Ika Astuti, Lusiana Dwi Wulandari, Eka Fitri Susiani
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/717
2022-11-09T14:16:41Z
bjop:Analytical-Medicinal
In Silico Study to Assess Antibacterial Activity from Cladophora Sp. on Peptide Deformylase: Molecular Docking Approach
Bintari, Yoni Rina
Risandiansyah, Rio
In silico
Antibacterial
Cladophora sp
Peptide Deformilase
Medicinal Chemistry
Increasing antibiotic-resistant pathogenic bacteria is a severe problem in the world. Therefore, there is a need to identify new drugs from natural products and also new drug targets. Cladophora sp. is a marine organism which is known to have bioactive compounds and a potential antibacterial. On the other hand, Peptide Deformylase (PDf) may prove to be a novel drug target since it is crucial for native peptide functioning in most pathogenic bacteria. This study screens for PDf inhibition activity of compounds from Cladophora sp. using molecular docking approach and screening the binding affinity of bioactive compounds against the peptide receptor PDf using Pyrex Autodock Vina software. Docking results were stored and visualized using Biovia Discovery Studio and PyMOL ligand. Ligands were obtained from previous literature in PubChem, and receptor peptide PDf from pathogenic bacteria: Pseudomonas aeruginosa (PDB ID:1N5N), Escherichia coli (PDB ID:1BSK), Enterococcus faecium (PDB ID:3G6N) and Staphylococcus aureus (PDB ID:1LQW), was obtained from the peptide data bank. The results of this screening show with ligand the highest binding affinity against PDf of P. aeruginosa, E. coli, E. faecium, and S. aureus is stearic acid (-5.9 kcal/mol), eicosapentaenoic acid (-6.6 kcal/mol), stearic acid (-5.8 kcal/mol), and stearic acid (-6.2 kcal/mol) respectively. The binding of natural compounds from Cladophora sp. with PDf models may provide a new drug with a different drug target for antibacterial potential.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-05-31
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/717
10.33084/bjop.v2i1.717
Borneo Journal of Pharmacy; Vol. 2 No. 1 (2019): Borneo Journal of Pharmacy; 20-23
2621-4814
10.33084/bjop.v2i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/717/666
Copyright (c) 2019 Yoni Rina Bintari, Rio Risandiansyah
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/726
2022-11-09T14:16:41Z
bjop:Editorial
Cover, Content, and Editorial Note from Borneo J Pharm Vol. 2 No. 1 May 2019
Borneo J Pharm, Chief Editor of
Borneo Journal of Pharmacy
Starting from this edition, Borneo J Pharm makes changes to the template in the article that will be published. The amendment aims to make it easier for readers to observe essential parts of each page of the article.In this edition, we succeeded in obtaining several achievements, including publishing all English-language articles and successfully gaining support from several international reviewers from various countries, such as Brunei Darussalam, Russia, India and Libya. We will ensure this achievement as a start and will continue to improve the quality of Borneo J Pharm in the future.This journal aims to publish high-quality articles dedicated to all aspects of the latest outstanding developments in the field but not limited to Pharmacology-Toxicology, Pharmacognosy-Phytochemistry, Pharmaceutical, Analytical Pharmacy-Medicinal Chemistry, Natural Product Development, Clinical-Community Pharmacy, Management Pharmacy, and other Pharmacy aspects. This edition contains six articles consisting of Pharmacology-Toxicology, Pharmaceutical, Analytical Pharmacy-Medicinal Chemistry, Natural Product Development, and Management Pharmacy topics.Editorial boards are fully aware that there is still room for improvement in this edition, hence with all humility willing to accept constructive suggestions and feedback for improvements to the publication for the next editions. The editorial board would like to thank the University, all editors and reviewers, and contributors of the scientific articles who have provided the repertoire in this issue. We hope that all parties, especially the contributors of the articles, could re-participate for the success of the publication in the next edition in November 2019.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-05-13
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Editorial Notes
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/726
10.33084/bjop.v2i1.726
Borneo Journal of Pharmacy; Vol. 2 No. 1 (2019): Borneo Journal of Pharmacy
2621-4814
10.33084/bjop.v2i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/726/2396
oai:journal.umpr.ac.id:article/836
2022-11-11T07:46:41Z
bjop:Analytical-Medicinal
Computational Drug Design against Ebola Virus Targeting Viral Matrix Protein VP30
Venkatesan, Arthi
Ravichandran, Lavanya
Dass, J Febin Prabhu
Ebola Virus
VP30
Molecular Docking
Molecular Dynamics Simulation
Drug Design
Medicinal Chemistry
Ebola viral disease (EVD) is a deadly infectious hemorrhagic viral fever caused by the Ebola virus with a high mortality rate. Until date, there is no effective drug or vaccination available to combat this condition. This study focuses on designing an effective antiviral drug for Ebola viral disease targeting viral protein 30 (VP30) of Ebola virus, highly required for transcription initiation. The lead molecules were screened for Lipinski rule of five, ADMET study following which molecular docking and bioactivity prediction was carried out. The compounds with the least binding energy were analyzed using interaction software. The results revealed that 6-Hydroxyluteolin and (-)-Arctigenin represent active lead compounds that inhibit the activity of VP30 protein and exhibits efficient pharmacokinetics. Both these compounds are plant-derived flavonoids and possess no known adverse effects on human health. In addition, they bind strongly to the predicted binding site centered on Lys180, suggesting that these two lead molecules can be imperative in designing a potential drug for EVD.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/836
10.33084/bjop.v2i2.836
Borneo Journal of Pharmacy; Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy; 71-81
2621-4814
10.33084/bjop.v2i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/836/967
https://journal.umpr.ac.id/index.php/bjop/article/view/836/968
Copyright (c) 2019 Arthi Venkatesan, Lavanya Ravichandran, J Febin Prabhu Dass
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/868
2022-11-11T07:46:41Z
bjop:Pharm-Tox
Immunomodulator Activity of Effervescent Granule of Wualae Fruit (Etlingera elatior (Jack) R.M. Smith) Based on Specific Phagocytic Activity
Fristiohady, Adryan
Zubaydah, Wa Ode Siti
Wahyuni, Wahyuni
Mirda, Mirda
Saripuddin, Saripuddin
Andriani, Rina
Purnama, La Ode Muhammad Julian
Sahidin, Sahidin
Effervescent granule
Wualae fruit
phagocytosis activity
Pharmacology
The previous study reported that Etlingera elatior (Wualae) has activity as immunostimulant with dose at 300 mg/kg BW and 400 mg/kg BW. Formulating natural product into effervescent granule (GE) can increase practicality and interest to consume traditional medicine. This study aims to investigate the immunostimulant activity of Wualae ethanolic extract in the effervescent granule. Wualae was macerated with ethanol then formulated into effervescent granule at dose 300 mg/kgBW and 400 mg/kgBW. Formulations were evaluated. Animals were divided into 4 groups and treated with: group I (positive control); group II (negative control); group III (GE dose at 300mg/kgBW); and group IV (GE at dose 400mg/kgBW) for 7 days and at days 8, groups were infected by Staphylococcus aureus intraperitoneally. Immunostimulant activity was measured by calculating the Specific Phagocytic Activity (SPA) of macrophage. Data collected from the evaluation and measurement of the SPA then analyzed using SPSS. Results from the evaluation were considered good except the moisture content of effervescent granule. Results from SPA was found that effervescent granule at dose 300 mg/kgBW and at dose 400 mg/kgBW have 26.33% and 32.5% consecutively with significance 0.02 (p<0.05). Thus, effervescent granule has comparable phagocytosis activity with positive control.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/868
10.33084/bjop.v2i2.868
Borneo Journal of Pharmacy; Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy; 35-40
2621-4814
10.33084/bjop.v2i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/868/969
Copyright (c) 2019 Adryan Fristiohady, Wa Ode Siti Zubaydah, Wahyuni Wahyuni, Mirda Mirda, Saripuddin Saripuddin, Rina Andriani, La Ode Muhammad Julian Purnama, Sahidin Sahidin
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/875
2022-11-11T07:46:41Z
bjop:Clin-Comm-Pharm
Evaluation of Rational Drug Use based on Indicators of Diseases and Facilities at Community Health Centers in Districts in Semarang
Febrinasari, Nisa
Rosyid, Abdur
Angelina, Leny
Facility Indicator
Prescribing Indicator
Community Health Center
Rational Drug Use
Semarang
Clinical Pharmacy
Rational drug use (RDU) is an indicator to evaluates a treatment given to patients, like proper medication, precise diagnosis, precise dosing. Community Health Center (CHC) has the risk of irrational drug use. In this study, researchers selected N and BL CHC, aiming to evaluate the prescribing indicators based on three diseases which are non-pneumonia acute respiratory infection (ARI), non-specific diarrhea and myalgia, and the facility indicators with DOEN (list of essential national medicines) availability and 20 mandatory drugs. This research was a descriptive-analytical study with cross-sectional methods where the data retrieval of the prescribing is taken from January to December 2018. The study used the normality test and homogeneity test before independent sample T-test, from the third outcome of the test, the N and BL CHC could be said to differ significantly of RDU. It can be concluded that rational drug use is reviewed from a prescribing indicator based on disease and facility indicator. The results of RDU are rational in N CHC, in contrast with BL CHC which is not rational with the results of the RDU in N CHC is 101.44% and BL CHC is 89.81%. The results of N CHC is better than BL CHC, which both CHCs have fulfilled the target of the government, for 68% in 2018. In both CHCs for the facility indicator, there are a DOEN and 20 essential medicines.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/875
10.33084/bjop.v2i2.875
Borneo Journal of Pharmacy; Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy; 119-124
2621-4814
10.33084/bjop.v2i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/875/970
Copyright (c) 2019 Nisa Febrinasari, Abdur Rosyid, Leny Angelina
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/897
2022-11-11T07:46:41Z
bjop:Analytical-Medicinal
Quantitative Analysis of Caffeine Levels in Local Coffee (Coffea sp) Powder on Dabo Island with UV-Vis Spectrophotometry
Hainil, Sri
Suhaera, Suhaera
Lirtri, Lirtri
Coffee powder
Caffeine
UV-Vis Spectrophotometry
Analytical Pharmacy
Coffee (Coffea sp) is the second-largest beverage consumed by people around the world whose process comes from the processing and extraction of coffee beans. Coffee has a chemical compound, one of which is caffeine. Caffeine is a crystal-shaped compound. Caffeine can be a tangible white powder or a shiny white needle-shaped, odorless caffeine, and caffeine has a bitter taste. The purpose of the study was to determine the caffeine levels of local ground coffee on the island of Dabo with the spectrophotometry UV-Vis method. Analysis of the ground coffee caffeine levels is quantitative determined using spectrophotometry UV-Vis. The equation of the calibration curve of caffeine is regression y = 0.1307x + 0.0112 with a correlation coefficient value (r) of 0.9993. Based on Indonesian National Standards (SNI) 01-7152-2006, The maximum limit of caffeine in foods and beverages is 150 mg/day and 50 mg/serving. The results of the analysis of caffeine levels from three samples of ground coffee circulating on Dabo Island each in 2 g were 0.3383 mg for Sample A; 0.3786 mg for Sample B; and 0.5803 mg for Sample C.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/897
10.33084/bjop.v2i2.897
Borneo Journal of Pharmacy; Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy; 82-86
2621-4814
10.33084/bjop.v2i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/897/971
Copyright (c) 2019 Sri Hainil, Suhaera Suhaera, Lirtri Lirtri
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/898
2022-11-11T07:46:41Z
bjop:Pharm-Phyto
Simplicia and Extracts Standardization from Jualing Leaves (Micromelum minutum Wight & Arn.) from South Kalimantan
Sutomo, Sutomo
Lestari, Herwina Dita
Arnida, Arnida
Sriyono, Agung
Micromelum minutum
Standardization
Simplicia
Specific parameter
Non-specific parameter
Pharmacognosy
Phytochemistry
Jualing (Micromelum minutum Wight & Arn.) is a plant from South Kalimantan that has the potential to be developed as natural medicine. This study aims to establish standardization which includes specific and non-specific parameters of M. minutum leaf simplicia and extracts from three growing locations, namely Banua Botanical Garden, Sultan Adam Forest Park, and Forest Areas with Specific Objects of Rantau, South Kalimantan. The method of setting standardization parameters refers to the Indonesian Herbal Pharmacopoeia and General Standard Extracts Parameters. Organoleptic standardization of simplicia is brownish-green, has a distinctive odor, has a bitter and slightly spicy taste. Microscopic observations showed the presence of stomata, cell walls, cytoplasm, calcium oxalate crystals, upper epidermis, palisade tissue, spongy tissue, cortex, xylem, phloem, lower epidermis, and trichomes. Water content test showed the results of 21.9-22.07%; ethanol extract content of 12.87-13.17%; drying losses 4.64-4.84%; total ash content of 6.04-6.14%; acid insoluble ash content 1.13-1.19%; Pb levels of 0.022-0.025 mg/kg; Cd levels of 0.017-0.020 mg/kg; and Hg levels <0.0004 mg/kg. Extract standardization shows thick green-black, thick-smelling extract and bitter taste. Micromelum minutum leaves contain alkaloids, flavonoids, saponins, terpenoids, tannins, anthraquinones, phenols, and glycosides. Thin Layer Chromatography profiles show the similarity of chemical compounds in each growth location. Other parameters are extract yield of 8.08-8.32%; moisture content of 6.07-6.27%; total ash content of 4.22-4.27%; and acid insoluble ash content 1.11-1.12%. All standardization parameters meet the requirements in the Media Materia Indonesia and the Republic of Indonesia Drug and Food Control Center.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/898
10.33084/bjop.v2i2.898
Borneo Journal of Pharmacy; Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy; 55-62
2621-4814
10.33084/bjop.v2i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/898/980
Copyright (c) 2019 Sutomo Sutomo, Herwina Dita Lestari, Arnida Arnida, Agung Sriyono
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/901
2022-11-11T07:46:41Z
bjop:Analytical-Medicinal
Characterization and Identification of Allergen Protein in Shrimp Before and After Heated with SDS-PAGE Method
Emawati, Emma
Idar, Idar
Ramadiyanti, Resta
Shrimp
Allergen Protein
Ion Exchange Chromatography
SDS-PAGE
Analytical Pharmacy
Food allergies are one of the most common allergies in Indonesian society. Generally, when children aged 5-6 years food allergies will disappear, except peanut allergies and allergies to seafood, such as fish, shellfish and crustaceans. This study aims to determine the pattern of separation of allergen proteins in shrimp using anion exchange column chromatography method and identify allergen proteins in shrimp using the sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) method. Protein extraction from shrimp using Phosphate buffer saline (PBS) pH 7.2 and centrifuged at 10,000 rpm for 10 min at 4°C. Protein separation was carried out by anion-exchange column chromatography method, and the fraction obtained was measured at 280nm wavelength. The highest yield at absorbance was identified by using SDS-PAGE. Polyacrylamide gel electrophoresis was used to determine the protein profile and molecular weight of shrimp extract. Coloring of protein bands using silver staining. Data were analyzed descriptively based on the migration value of the sample protein bands compared to the marker protein band (Rf). The results of protein allergen profile analysis on shrimp using SDS-PAGE showed that the shrimp contained a protein band with a molecular weight of 37.77 kDa for cooked shrimp and 37.03 kDa for fresh shrimp.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/901
10.33084/bjop.v2i2.901
Borneo Journal of Pharmacy; Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy; 87-93
2621-4814
10.33084/bjop.v2i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/901/972
Copyright (c) 2019 Emma Emawati, Idar Idar, Resta Ramadiyanti
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/915
2022-11-11T07:46:41Z
bjop:Analytical-Medicinal
Active Fractions of Methanol Crude Obtained from Acacia seyal gum: Antioxidant Capacity using FTIR Analysis
Elnour, Ahmed A M
Mirghani, Mohamed Elwathig Saeed
Kabbashi, Nassereldeen A
Alam, Md Zahangir
Musa, Khalid Hamid
Acacia seyal gum
Pharmacutical ingredient
FTIR spectroscopy
Micro-nutrients
Analytical Pharmacy
The present study is on Acacia seyal gum (ASG), which is an exudate from Talha tree. It provides a rich source of polyphenolics compounds that are used traditionally in folk medicine. The study aims to determine the antioxidant capacity (AC) and functional groups of ASG and Prebio-T-commercial (PTC) samples. The methanol crude extracts of both ASG and PTC have fractioned into chloroform (CHF), hexane (HF), acetone (AF) and methanol (MF) using solvent-solvent portion. Both ferric reducing antioxidant power (FRAP), and cupric reducing antioxidant capacity (CUPRAC) assays for each fraction examined. Crude methanol extracts (CME) and its active compositions also analysed carefully using Fourier Transform Infrared Spectroscopy (FTIR) technique. The findings presented a wide variety of functional groups provided by the FTIR spectra (eights bands approximately. Regarding cupric reducing antioxidant capacity (CUPRAC), the methanol crude extracts values are 888.6±4.57 mg TE/100g extract, for PTC as compared to 474.3± 2.23 mg TE/100g of extract for ASG. However, both methanol and acetone fractions revealed significantly (p ≤ 0.05) high FRAP values ranged between 599.8±7.5 and 741.8±5.8 mg TE/100g fraction; for PTC and ASG, respectively. While CUPRAC showed insignificant (p ≥ 0.05) same values 356.1±2.62 mg TE/100g of fraction; for MF of both PTC and ASG respectively. Therefore, in this study, methanolic fractions (MFs) are found to be more effective than acetone fractions (AFs), except for CHF and HF. Finally, the antioxidant activity of the active fraction has provided some evidence regarding its functional groups which may have used in traditional medicine.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/915
10.33084/bjop.v2i2.915
Borneo Journal of Pharmacy; Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy; 94-107
2621-4814
10.33084/bjop.v2i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/915/973
Copyright (c) 2019 Ahmed Adam M Elnour, Mohamed Elwathig Saeed Mirghani, Nassereldeen A Kabbashi, Md Zahangir Alam, Khalid Hamid Musa
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/928
2022-11-11T07:46:41Z
bjop:Nat-Pro-Dev
Antibacterial Activity Test of Ethanol Extract Pineapple (Ananas comosus (L.) Merr.) Peel against Growth of Propionibacterium acnes
Fitriyanti, Fitriyanti
Hendrawan, Muhammad Nur Rahman
Astuti, Karunita Ika
pineapple peel extract
antibacterial
Propionibacterium acnes
Natural Product Development
Pineapple peel (Ananas comosus (L.) Merr.) is waste from the pineapple fruit. The purpose of this study was to determine the content of pineapple peel extract and to antibacterial activity in various concentrations effective in inhibiting the growth of Propionibacterium acnes. The pineapple peel extract is made by using the extraction method in the form of maceration. The method used in the inhibitory test using the three replication samples in each treatment group. The sample consisted of 10 treatment groups ie pineapple peel extract concentration 12.5%, 25%, 37.5%, 50%, 62.5%, 75%, 87.5%, and 100%, as well as positive and negative control. The results obtained from pineapple peel screening contain flavonoid and saponin compounds. The data analysis shows that pineapple peel extract concentrations of 50%, 62.5%, 75%, 87.5%, and 100% had inhibitory zones with the medium-strong category while clindamycin as the control has a strong inhibition zone. The conclusion of this research proves that pineapple peel extract has antibacterial power to P. acnes with effective concentration is 100% with the strong category.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/928
10.33084/bjop.v2i2.928
Borneo Journal of Pharmacy; Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy; 108-113
2621-4814
10.33084/bjop.v2i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/928/974
Copyright (c) 2019 Fitriyanti Fitriyanti, Muhammad Nur Rahman Hendrawan, Karunita Ika Astuti
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/981
2022-11-11T07:46:41Z
bjop:Pharmaceut
Formula Optimization of Annona muricata Folium Ethanolic Extract of Anti Acne Gel Formulation using Factorial Design Method
Putri, Aristha Novyra
Laila, Noor
Forestryana, Dyera
Acne
Annona muricata folium
Optimization
Gel
Acne is a pile of oil glands in the skin that are actively being clogged by dirt and infection because of Propionibacterium acnes, Staphylococcus aureus, and Staphylococcus epidermidis. The treatment for acne can use herbal ingredients, one of which is Soursop (Annona muricata L.) leaves ethanolic extract. Annona muricata folium ethanolic extract is known to have alkaloid, flavonoid and polyphenol compounds which can inhibit the growth of P. acnes, S. epidermidis, and S. aureus. Suitable dosage forms for anti-acne preparations are gels because the gel contains much water so that it provides a cooling effect on the skin due to inflammation. The purpose of this study was to determine the impact of carbopol 940 and Propylene glycol on the physical characteristics of the gel preparation and determine the optimum formula of the gel preparation using factorial design software 22 so that the gel preparation was made in four formulas. The data obtained were then analyzed using Design-Expert® and ANOVA software with a confidence level of 95%, and the determination of the optimum formula based on the optimum superimposed contour plot area. The results of the study using a factorial design approach are known that Propylene glycol has an effect on increasing the spreadability and pH while carbopol 940 has a more significant impact on the increase in adhesion and viscosity, and the optimum area of the composition of carbopol 940 1.536% and propylene glycol 5% was obtained.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/981
10.33084/bjop.v2i2.981
Borneo Journal of Pharmacy; Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy; 63-70
2621-4814
10.33084/bjop.v2i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/981/975
Copyright (c) 2019 Aristha Novyra Putri, Noor Laila, Dyera Forestryana
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/982
2022-11-11T07:46:41Z
bjop:Pharm-Tox
Evaluation of Biochemical Parameters of Rats Fed with Corn Flour Supplemented with Cricket (Acheta gossypii) Proteins
Ehoche, Elijah Edache
Helmina, Akanya
Sherifat, Adefolalu Funmilola
diets
supplementation
corn
cricket
Biochemistry
African staple diets are mainly of protein-deficient corn. Dried yellow corn was fermented, dried, ground and supplemented with 5% and 10% of cricket (Acheta gossypii) flour. A standard diet of 5% and 10% soybean proteins-based corn flour was also prepared. The diets were fed to albino rats for four weeks. Standard methods for the serum levels of alkaline phosphatase (ALP), aspartate transaminase (AST), alanine transaminase (ALT), total proteins (TP), and albumin were determined in albino rats using 5% and 10% soybean supplemented corn diets as standard diets. The serum levels of ALP, AST, ALP, TP, and albumin in the rats fed with cricket supplemented diets were in the range of the normal healthy animals but were significantly different from the cornflour and soybean supplemented diets such that the ALP and AST values of the rats fed on the cornflour significantly decreased over the soybean supplemented and cricket supplemented experimental diets. The ALT activity, TP, and albumin levels of the rats fed the cornflour, and the soybean supplemented diets were significantly lower than those fed on the cricket protein supplemented diet (p <0.05). Supplementing corn with crickets has shown improvement in the nutritional quality of corn, therefore, may be used to solve the malnutrition
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/982
10.33084/bjop.v2i2.982
Borneo Journal of Pharmacy; Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy; 41-47
2621-4814
10.33084/bjop.v2i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/982/976
Copyright (c) 2019 Elijah Edache Ehoche, Akanya Helmina, Adefolalu Funmilola Sherifat
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/994
2020-03-06T01:30:41Z
bjop:Pharmaceut
oai:journal.umpr.ac.id:article/1020
2022-11-11T07:46:41Z
bjop:Pharm-Tox
The Potential of Walnut Seeds (Canarium indicum L.) in Repairing The Genotoxicity Effect of Mercury on Mice Erythrocytes
Wibowo, Cakra Haryo
Oktarina, Essy
Wardani, Rafika Destiana
Ngibad, Khoirul
Walnut
Ellagic Acid
Genotoxicity
Mercury
Micronucleus Assay
Toxicology
Hydrargyrum (familiar as mercury) is a persistent transition metal element. They are known as bio-accumulative properties that are dangerous to the environment and has serious damaging effects on biota, including genetic changes or mutagenesis. Moreover, it can accumulate indirectly in the human body due to the consumption of products that have contaminated. Whereas, ellagic acid has reported as one of 13 flavonoid compounds that have potential as an anti-mutagen and anti-cancer in the walnuts seeds. This study was aimed to ensure the potential extent of ellagic acid extracts in walnut seeds to reducing and repairing the genotoxicity effects of mercury. Therefore, using the experimental method, this study was divided into several test treatments. Two controls treatment as a comparison of the presence of micronucleus with group tests that given a 20 ppm mercury dosage. Then continued with the addition of walnut seed extract with various dosage (10, 15, and 20 ppm) by oral injection continuously for two weeks as a recovery process to reducing and repairing the genotoxicity effect of mercury. The significant results showed that there are differences between pre and post-treatment. It indicated that the extract has the potential for improving and reducing the genotoxicity effect of mercury. The data were evaluated and obtained the total micronucleus from the smear of peripheral blood of mice by comparing the total micronucleus before and after giving of walnut extract.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1020
10.33084/bjop.v2i2.1020
Borneo Journal of Pharmacy; Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy; 48-54
2621-4814
10.33084/bjop.v2i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1020/977
Copyright (c) 2019 Cakra Haryo Wibowo, Essy Oktarina, Rafika Destiana Wardani, Khoirul Ngibad
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/1044
2022-11-11T07:46:41Z
bjop:Clin-Comm-Pharm
The Rationality of Antibiotics Use on Inpatient Department of Pediatric in One of the Hospital in Cimahi
Septiani, Vina
Kartidjo, Pudjiastuti
Nurdiani, Fenny Asri
Rationality
Antibiotic
Pediatric
Clinical Pharmacy
The purpose of this study is to assess the rationality of the use of antibiotics from inpatients in one hospital in Cimahi, West Java. The research about rationality analysis of antibiotics at pediatric inpatient in one of the hospitals in Cimahi was done retrospectively use descriptive analysis design. The data source was the medical record of a patient who treated at the children's inpatient ward from January through March 2017. The result shows that 39% of infected patients were children under one-year-old. Three significant cases of diseases that occurred in the period were bronchopneumonia, typhoid fever, and typhoid fever+bronchopneumonia. Antibiotics therapy was given as single therapy as well as combination, where cefotaxime (51%) and ceftriaxone (42%) were the most antibiotics widely used as single therapy. Antibiotic use at children inpatient ward during the period January – March 2017 on bronchopneumonia, typhoid fever, and typhoid fever + bronchopneumonia patients was not 100% rational referring to criteria: correct diagnosis, correct indication, the correct drug of choice, correct dosage, correct method, and correct time interval of drug administration.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1044
10.33084/bjop.v2i2.1044
Borneo Journal of Pharmacy; Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy; 125-132
2621-4814
10.33084/bjop.v2i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1044/978
Copyright (c) 2019 Vina Septiani, Pudjiastuti Kartidjo, Fenny Asri Nurdiani
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/1070
2022-11-11T07:46:41Z
bjop:Nat-Pro-Dev
Antioxidant Activity of Ethanolic Extract from Tandui Leaves (Mangifera rufocostata Kosterm.) by DPPH Radical Scavenging Method
Saputri, Revita
Melati, Tia Mariati Risma
Fitriyanti, Fitriyanti
Antioxidant
Ethanol Extract
Tandui
Mangifera ruficostata Kosterm
DPPH
Natural Product Development
Tandui (Mangifera rufocostata Kosterm.) is a typical plant from South Kalimantan which belongs to the genus of Mangifera. Several species of Mangifera are known to have antioxidant activity. This study aimed to determine the antioxidant activity of ethanol extract of Tandui leaves. Tandui leaves that were obtained from the maceration method used 70% ethanol. Antioxidant activity was conducted quantitative using the DPPH (2,2-diphenyl-1-picrylhydrazil) method. The result of the antioxidant activity of Ethanol extract of Tandui leaves quantitatively obtained IC50 value was 60.7042 µg/mL. The ethanol extract of Tandui leaves has strong antioxidant activity
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1070
10.33084/bjop.v2i2.1070
Borneo Journal of Pharmacy; Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy; 114-118
2621-4814
10.33084/bjop.v2i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1070/979
Copyright (c) 2019 Revita Saputri, Tia Mariati Risma Melati, Fitriyanti Fitriyanti
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/1082
2020-04-15T01:05:32Z
bjop:Analytical-Medicinal
Prediction of the Antiinflammatory Activity of New S-alkyl Derivatives of 1,2,4-triazol-3-thiones Using the PASS Computer Program and Molecular Docking
Chalenko, Natalya Mykolaivna
Syrovaya, Anna Olegovna
Kobzar, Natalya P
Rakhimova, Maryna V
Sych, Irina A
Sych, Igor Vladimirovich
Molecular docking
Antiinflammatory activity
1,2,4-triazol-3-thiones
PASS
COX-2
Medicinal Chemistry
The strategy of rational approaches to the search for selective COX-2 inhibitors as potential antiinflammatory agents has been proposed and elaborated. It is based on the use of PASS-prediction and molecular docking. The choice of the basic structure of 4-amino-3-thio-1,2,4-triazole as a promising object of chemical modification has been substantiated. Using a modification of the primary molecule, a virtual library of S-derivatives of 5-substituted 4-amino(pyrrol)3-thio-4H-1,2,4-triazoles in the amount of 100 compounds (ten groups) has been obtained by introducing various pharmacophore fragments. Based on the analysis of the results of the PASS-prediction and molecular docking, six of the ten planned groups of compounds have been selected for the synthesis as promising selective COX-2 inhibitors. The reliability of the prediction results has already been confirmed for one of the promising group 4-amino-5-(pyridine-4-yl)-1,2,4-triazole (4Н)-3-yl-thioacetamides.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-02-27
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
https://journal.umpr.ac.id/index.php/bjop/article/view/1082
10.33084/bjop.v3i1.1082
Borneo Journal of Pharmacy; Vol. 3 No. 1 (2020): Borneo Journal of Pharmacy; 36-43
2621-4814
10.33084/bjop.v3i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1082/1123
https://journal.umpr.ac.id/index.php/bjop/article/view/1082/1325
Copyright (c) 2020 Natalya Mykolayivna Chalenko, Anna Olegovna Syrovaya, Natalya P Kobzar, Maryna V Rakhimova, Irina A Sych, Igor Vladimirovich Sych
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/1083
2022-11-11T07:46:41Z
bjop:Editorial
Cover, Content, and Editorial Note from Borneo J Pharm Vol. 2 No. 2 November 2019
Borneo J Pharm, Chief Editor of
Borneo Journal of Pharmacy
Alhamdulillahirabbil ‘alamin. The next edition of Borneo Journal of Pharmacy (Borneo J Pharm), has been published at November 2019. Starting from this edition, Borneo J Pharm make changes to the template in the article that will be published. The amendment aims to make it easier for readers to observe essential parts of each page of the article. The aim of this journal is to publish high-quality articles dedicated to all aspects of the latest outstanding developments in the field but not limited to Pharmacology-Toxicology, Pharmacognosy-Phytochemistry, Pharmaceutical, Analytical Pharmacy-Medicinal Chemistry, Natural Product Development, Clinical-Community Pharmacy, Management Pharmacy, and other Pharmacy aspects. This edition contains 13 articles consisting of Pharmacology-Toxicology, Pharmacognosy-Phytochemistry, Pharmaceutical, Analytical Pharmacy-Medicinal Chemistry, Natural Product Development, and Clinical-Community Pharmacy topics. Editorial boards are fully aware that there are still room for improvement in this edition, hence with all humility willing to accept constructive suggestions and feedback for improvements to the publication for the next editions. The editorial board would like to thank the University, all editors and reviewers, and contributors of the scientific articles who have provided the repetoire in this issue. We hope that all parties, especially the contributors of the articles, could re-participate for the success of the publication in the next edition on May 2020
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2019-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Editorial Notes
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1083
10.33084/bjop.v2i2.1083
Borneo Journal of Pharmacy; Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy
2621-4814
10.33084/bjop.v2i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1083/2392
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/1236
2020-04-15T01:05:30Z
bjop:Pharmaceut
Design of Experiments Assessment for the Determination of Moisture Content in Five Herbal Raw Materials Contained in Tea Products
Castillo, Luis
Baltodano, Eleaneth
Ramírez, Nils
Vargas, Rolando
Hanley, Georgia
Design of Experiments
Herbal product
Tea
Quality control
Moisture content
Quality control
Research interest in natural raw materials is rapidly growing due to the high demand for natural products like herbal teas. Their quality control has a direct impact on safety and efficacy. The aim of this study was to evaluate the impact of sample’s mass and temperature on moisture content in Camellia sinensis (Black tea), Cassia fistula (Senna), Chamaemelum nobile (Chamomille), Lippia alba (Juanilama) and Tilia platyphyllos (Linden) with a gravimetric method developed through a full factorial 32 DoE. A response optimizer was executed in order to establish the test conditions that allow obtaining a response according to a target value from a certified method. DoE’s ANOVA shows reproducibility for Camellia sinensis, Cassia fistula, and Lippia alba. Also, the method’s model is able to explain the response variability for all samples based on the R2 (adj). The composite desirability for the proposed conditions of analysis for the five herbal materials is satisfactory according to each target value. However, the lack of reproducibility in Chamaemelum nobile and Tilia platyphyllos and also, the response prediction problems according to the R2 (pred) for Cassia fistula and Chamaemelum nobile, suggest the execution of further studies for them. Therefore, the present method is considered to be adequate for the analysis of moisture content in Camellia sinensis and Lippia alba raw herbs.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-02-27
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
https://journal.umpr.ac.id/index.php/bjop/article/view/1236
10.33084/bjop.v3i1.1236
Borneo Journal of Pharmacy; Vol. 3 No. 1 (2020): Borneo Journal of Pharmacy; 22-35
2621-4814
10.33084/bjop.v3i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1236/1122
https://journal.umpr.ac.id/index.php/bjop/article/view/1236/1324
Quality control, Natural product quality control
Copyright (c) 2020 Luis Castillo, Eleaneth Baltodano, Nils Ramírez, Rolando Vargas, Georgia Hanley
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/1242
2020-04-15T01:05:28Z
bjop:Nat-Pro-Dev
Test on the Antioxidant Activities of Methanol Extract of Bidara Leaves (Ziziphus spina-christi L.) using the DPPH Radical Immersion Method
Pambudi, Dwi Bagus
Fajriyah, Nuniek Nizmah
Shalekhah, Vidiah Rizka
DPPH
IC50
Bidara
Ziziphus spina-christi L
Antioxidant
Pharmacognosy-Phytochemistry
Bidara (Ziziphus spina-christi L.) is a tropical tree originating from Sudan in which it is commonly known as "Nebeq" in Saudi Arabia. It is of a bioactive compound - a flavonoid compound, which is the potential to be used as an antioxidant. It is capable of inhibiting any cell damages caused by free radicals. This study aimed to measure the activities of the free radicals in methanol extracts of Z. spina-christi leaves. The process of extracting the Z. spina-christi leaves was carried out through the maceration method using methanol as a solvent. The qualitative analysis of chemical compounds with certain eluents using thin-layer chromatography (TLC) was purposely to determine the groups of active compounds in extracts. The measurement of antioxidant activities was carried out using the 1,1-Diphenyl-2-picryl Hidrazyl (DPPH) immersion method in which absorption was measured at a maximum wavelength of 513 nm. The results showed that the methanol extract of Z. spina-christi leaves had a very weak antioxidant activity with the IC50 value of 466.804 μg/ml. The results of the bioautographic profile showed the presence of flavonoid compounds, phenols, saponins, and tannins.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-02-27
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
https://journal.umpr.ac.id/index.php/bjop/article/view/1242
10.33084/bjop.v3i1.1242
Borneo Journal of Pharmacy; Vol. 3 No. 1 (2020): Borneo Journal of Pharmacy; 44-51
2621-4814
10.33084/bjop.v3i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1242/1124
https://journal.umpr.ac.id/index.php/bjop/article/view/1242/1326
Copyright (c) 2020 Dwi Bagus Pambudi, Nuniek Nizmah Fajriyah, Vidiah Rizka Shalekhah
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/1245
2020-04-15T01:05:27Z
bjop:Pharm-Phyto
Phytochemical Screening and Antioxidant Activity of Ethanolic Extract of Cawat Hanoman Stem (Bauhinia aculeata L.) using DPPH Method
Muthia, Rahmi
Hidayatullah, Muhammad
Hidayati, Rahmi
Antioxidant
DPPH
Ethanolic extract
Bauhinia aculeata L.
Cawat hanoman
Phytochemistry
The free radical is an unstable molecule because contains one or two unpaired electrons. The antioxidant substance is a simple way to decrease the illness caused by free radicals. Cawat hanoman (Bauhinia aculeata L.) was known to contain tannin components one of the benefits as an antioxidant. This research aims to determine the antioxidant activity of the B. aculeata stem tested by qualitatively used thin-layer chromatography (TLC) and quantitatively using the DPPH method. Bauhinia aculeata stem was extracted using a maceration extract method with 96% ethanol. Antioxidant activity test was done qualitatively by eluent of ethyl acetate : methanol : purified water (6 : 2 : 1) using TLC and quantitatively using the DPPH method. The result of antioxidant activity from 96% ethanol extract of B. aculeata stem qualitatively showed the presence of yellow spots on a purple background at TLC after syringed DPPH 0.5 mM and quantitative test that resulted in an IC50 of 21.862 μg/mL. These results indicate that 96% ethanol extract of B. aculeata has very strong antioxidant activity.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-02-27
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
https://journal.umpr.ac.id/index.php/bjop/article/view/1245
10.33084/bjop.v3i1.1245
Borneo Journal of Pharmacy; Vol. 3 No. 1 (2020): Borneo Journal of Pharmacy; 15-21
2621-4814
10.33084/bjop.v3i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1245/1121
https://journal.umpr.ac.id/index.php/bjop/article/view/1245/1323
Copyright (c) 2020 Rahmi Muthia, Muhammad Hidayatullah, Rahmi Hidayati
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/1246
2020-04-15T01:05:25Z
bjop:Pharm-Tox
Effect of Broccoli (Brassica oleracea L. var. italica) Extract on Bleeding Time in Male White Mice (Mus musculus L.)
Sammulia, Suci Fitriani
Almahdy, Almahdy
Rezky, Aldo Wahyu
Bleeding time
Brassica oleracea
Hemostatic
Pharmacology-Toxicology
Cessation of bleeding is influenced by many factors including the type of medication used. The use of drugs to stop bleeding can be done in various ways, one of which is the use of traditional medicine. One of the traditional plants that can be used as a stop bleeding is broccoli (Brassica oleracea L. var. italica) which has a fairly high vitamin K content, where is efficacious as hemostatic. This study aims to determine the effect of broccoli on the bleeding time of mice tail cuts. The first group was negative control (Na-CMC), the second group was positive control (tranexamic acid), while groups three, four, and five were broccoli extract dose of 20, 40, and 60 mg/kg BW, respectively. All treatments were given orally for seven days. Bleeding time was calculated from the initial blood loss until the blood stopped (tail bleeding I method) and the data were analyzed with the ANOVA one way test and the post hoc Least Significant Difference (LSD) statistical test. The results showed that there were differences in the time to stop bleeding in the treatment control group at a dose of 20 mg/kg BW (122.60 ± 29.535 seconds), 40 mg/kg BW (102.40 ± 9.607 seconds) and 60 mg/kg BW (90.40 ± 3.845 seconds). From these results, it can be concluded that the extract of broccoli at a dose of 60 mg/kg BW gives the best results as hemostatic, while the effect is almost similar to the positive control group.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-02-27
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
https://journal.umpr.ac.id/index.php/bjop/article/view/1246
10.33084/bjop.v3i1.1246
Borneo Journal of Pharmacy; Vol. 3 No. 1 (2020): Borneo Journal of Pharmacy; 1-6
2621-4814
10.33084/bjop.v3i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1246/1119
https://journal.umpr.ac.id/index.php/bjop/article/view/1246/1320
Copyright (c) 2020 Suci Fitriani Sammulia, Almahdy Almahdy, Aldo Wahyu Rezky
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/1250
2020-04-15T01:05:24Z
bjop:Pharm-Phyto
Preliminary Phytochemical Analysis and Antioxidants Activities of Ethanolic Extract from Gomphrena serrata Whole Plant
Nandini, Kodukothanahalli Naganna
Palaksha, Mekerahalli Narayanappa
Mamatha, Belakavadi Shivalingu
Lekhana, Anasosalu Ramesh
Antioxidant
Free radicals
Gomphrena serrata
Phytochemical
Scavenging activity
Phytochemistry
The present study was designed to investigate the phytochemical analysis and antioxidant activities of the whole plant of Gomphrena serrata. Gomphrena serrata widely distributed in South America, North America, and India. These plant parts are used as traditional medicine for the treatment of several ailments. This study aims to assess the phytochemical and free radical scavenging of ethanolic extract of G. serrata present in the plant. The preliminary phytochemical study was performed by standard method. The whole plant of G. serrata proved the presence of bioactive constituents such as carbohydrates, alkaloids, steroids, glycosides, triterpenoids, protein and amino acids, saponins, as well as flavonoids. The in-vitro antioxidant study was performed on the ethanolic extract of shade-dried of the whole plant, which determined by hydrogen peroxide, hydroxyl radical, and 1,1-diphenyl-2-picrylhydrazyl (DPPH) 100 µg/ml assay and was compared to ascorbic acid. The ethanolic extract of the whole plant of G. serrata shows the strong free radical scavenging activity. The present study was the proof for ethanol extract of G. serrata which have medicinally significant and bioactive compounds since these plant species are used as traditional medicine for the treatment of various diseases.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-02-27
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
https://journal.umpr.ac.id/index.php/bjop/article/view/1250
10.33084/bjop.v3i1.1250
Borneo Journal of Pharmacy; Vol. 3 No. 1 (2020): Borneo Journal of Pharmacy; 7-14
2621-4814
10.33084/bjop.v3i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1250/1120
https://journal.umpr.ac.id/index.php/bjop/article/view/1250/1321
Copyright (c) 2020 Kodukothanahalli Naganna Nandini, Mekerahalli Narayanappa Palaksha, Belakavadi Shivalingu Mamatha, Anasosalu Ramesh Lekhana
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/1267
2020-05-22T05:08:48Z
bjop:Pharm-Phyto
Pharmacognostic Study of Sangkareho Root (Callicarpa longifolia Lam.) from Pelaihari, South Kalimantan
Fitriyanti, Fitriyanti
Yusmalina, Yusmalina
Muthia, Rahmi
Callicarpa longifolia Lam
Pharmacognostic
Thin-layer chromatography
Pharmacognosy-Phytochemistry
Sangkareho (Callicarpa longifolia Lam.) is used traditionally by one of Kalimantan's indigenous tribes, the Dayak Tunjung tribe as a medicine for colds and inflammation, where the plant parts used are the roots. Considering its very potential prospects, research aimed at providing a scientific basis for plant pharmacognostic data needs to be carried out with qualitative methods. The qualitative examination is done by several methods including test identification of organoleptic, macroscopic, microscopic, and chemical compounds. Organoleptic test results showed that the roots have a light brown color, bitter and slightly spicy, and a rather pungent odor. Microscopic test results showed sangkareho root has a length of ± 90 cm; width of ± 1 cm; and for the form of a spear with a ride root system. Microscopic observations are found in the form of epidermal cells, exodermis, cortex, endodermis, bearing files, calcium oxalate crystals, and stone cells. The identification of chemical compounds showed positive results against alkaloids, flavonoids, saponins, and triterpenoids. The thin-layer chromatography profile shows four separate stains with eluent ethyl acetate : methanol : water in a ratio of 8 : 2 : 1, respectively.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-05-21
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
https://journal.umpr.ac.id/index.php/bjop/article/view/1267
10.33084/bjop.v3i2.1267
Borneo Journal of Pharmacy; Vol. 3 No. 2 (2020): Borneo Journal of Pharmacy; 58-63
2621-4814
10.33084/bjop.v3i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1267/1232
https://journal.umpr.ac.id/index.php/bjop/article/view/1267/1240
Copyright (c) 2020 Fitriyanti Fitriyanti, Yusmalina Yusmalina, Rahmi Muthia
oai:journal.umpr.ac.id:article/1269
2020-04-15T01:05:23Z
bjop:Editorial
Cover, Content, and Editorial Note from Borneo J Pharm Vol. 3 No. 1 February 2020
Borneo J Pharm, Chief Editor of
Borneo Journal of Pharmacy
Alhamdulillahirabbil ‘alamin. The next edition of Borneo Journal of Pharmacy (Borneo J Pharm), has been published in February 2020. Starting from this edition, Borneo J Pharm increases the frequency of publishing four times a year. This change aims to improve the circulation of the best articles published by Borneo J Pharm. Also, starting from this edition, Borneo J Pharm applying the publish-as-you-go issue to present the title of the article that has been received as early as possible in order to increase the chances of readability and quotation of articles in Borneo J Pharm.Starting in the 2019 edition, Borneo J Pharm has been accepted for indexing in EMBASE by Elsevier. This is an acknowledgment of the quality of the publications presented by Borneo J Pharm. In addition, Borneo J Pharm has also been accredited at SINTA in rank 3. In the future, Borneo J Pharm will try to improve the accreditation rank and register with other indexers such as ESCI and ASEAN Citation Index.This edition contains six articles consisting of Pharmacology-Toxicology, Pharmacognosy-Phytochemistry, Pharmaceutical, Analytical Pharmacy-Medicinal Chemistry, and Natural Product Development. This edition includes writings from four countries including Indonesia, India, Ukraine, and Costa Rica. The authors come from several institutions, including Sekolah Tinggi Ilmu Kesehatan Mitra Bunda Persada Batam, Bharathi College of Pharmacy, Sekolah Tinggi Ilmu Kesehatan Borneo Lestari, Universidad de Costa Rica, Kharkiv National Medical University, National University of Pharmacy, Hon. Prof. M. S. Bokarius Kharkiv Research Institute of Forensic Examinations, and Universitas Muhammadiyah Pekajangan Pekalongan.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-02-27
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Editorial Notes
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1269
10.33084/bjop.v3i1.1269
Borneo Journal of Pharmacy; Vol. 3 No. 1 (2020): Borneo Journal of Pharmacy
2621-4814
10.33084/bjop.v3i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1269/2397
oai:journal.umpr.ac.id:article/1316
2020-05-22T05:08:46Z
bjop:Clin-Comm-Pharm
Potential Drug-drug Interactions Analysis in Children Out-patients with Bronchopneumonia Medication Prescriptions
Zulfa, Ilil Maidatuz
Yunitasari, Fitria Dewi
Dewi, Susanty Kartika
Drug Interactions
Bronchopneumonia
Children
Outpatients
Pharmacology
Drug-drug interactions (DDIs) is defined as the alteration of efficacy and toxicity of some drugs in the presence of other drugs. In the treatments of bronchopneumonia in outpatient settings, there is a lack of documentation of DDIs. This study was aimed to observe the potential DDIs on the prescriptions of children with bronchopneumonia. An observational and cross-sectional study was conducted on outpatient children with bronchopneumonia prescriptions during 2017. Potential for DDI was identified by online drug interaction checkers. The potential DDI then classified based on its severity (minor, moderate, and major) and mechanism (pharmacokinetic and pharmacodynamic). Among 86 prescriptions analyzed, potential DDIs observed at 48.84% of it. Of that, there were 67 potential DDIs where 72.34% of it were categorized as moderate. The majority of potential DDIs was pharmacodynamic interaction (76.12%) with the most frequently involved drug pair was Ephedrine-Salbutamol (29.85%). Children outpatients with bronchopneumonia are at risk of potential DDIs, especially to minor and moderate potential DDIs. Prescriptions screening for potential DDIs followed by monitoring of therapeutical effects and associated adverse drug events will optimize patient safety.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-05-21
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
https://journal.umpr.ac.id/index.php/bjop/article/view/1316
10.33084/bjop.v3i2.1316
Borneo Journal of Pharmacy; Vol. 3 No. 2 (2020): Borneo Journal of Pharmacy; 79-83
2621-4814
10.33084/bjop.v3i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1316/1234
https://journal.umpr.ac.id/index.php/bjop/article/view/1316/1247
Copyright (c) 2020 Ilil Maidatuz Zulfa, Fitria Dewi Yunitasari, Susanty Kartika Dewi
oai:journal.umpr.ac.id:article/1318
2020-06-27T14:29:43Z
bjop:Pharm-Tox
Level of Cytokine Interleukin-6 and Interleukin 1-β on Infectious Rat Model Treated with Etlingera elatior (Jack) R.M. Smith Fruit Extract as Immunomodulator
Fristiohady, Adryan
Wahyuni, Wahyuni
Malik, Fadhliyah
Yusuf, Muhammad Ilyas
Salma, Wa Ode
Hamsidi, Rini
Talebong, Fredy
Yuliansyah, Yuliansyah
Purnama, La Ode Muhammad Julian
Saripuddin, Saripuddin
Sahidin, Sahidin
Etlingera elatior (Jack) R.M. Smith
Immunomodulator
Plasma IL-1β
Plasma IL-6
Pharmacology
Etlingera elatior (Jack) R.M Smith or locally in Southeast Sulawesi known as Wualae fruit has activity as an immunomodulator by increasing phagocytosis activity. Prior studies have been conducted to observe the effect of E. elatior as an immunomodulator, thus further study is needed to observe the production of cytokines such as IL-1β and IL-6 which are responsible for the immune responses. Etlingera elatior fruit macerated with 96% ethanol for three days and produced a total of ±74.6 g concentrated extract. Experimental animals used were divided into four groups (n=4) and treated orally once a day for seven days as follows: group I (0.5% Na CMC); group II (Stimuno®); group III (E. elatior fruit extract dose of 300 mg/kg BW); and group IV (E. elatior fruit extract dose of 400 mg/kg BW). On the eight-day, animals were infected with Staphylococcus aureus intraperitoneally and left for an hour. Thereafter, blood was collected and assayed using ELISA Kit (Elabscience rat IL-1β and Elabscience rat IL-6). Results demonstrated that group IV increased levels of IL-1β and group III and IV increased level of IL-6 (p<0.05). Increased levels of IL-1β and IL-6 are associated with phagocytosis in the immune response. In conclusion, E. elatior fruit extract at doses of 300 and 400 mg/kg BW increases levels of IL-1β and IL-6.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-05-21
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
https://journal.umpr.ac.id/index.php/bjop/article/view/1318
10.33084/bjop.v3i2.1318
Borneo Journal of Pharmacy; Vol. 3 No. 2 (2020): Borneo Journal of Pharmacy; 52-57
2621-4814
10.33084/bjop.v3i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1318/1230
https://journal.umpr.ac.id/index.php/bjop/article/view/1318/1238
Copyright (c) 2020 Adryan Fristiohady, Wahyuni Wahyuni, Fadhliyah Malik, Muhammad Ilyas Yusuf, Wa Ode Salma, Rini Hamsidi, Fredy Talebong, Yuliansyah Yuliansyah, La Ode Muhammad Julian Purnama, Saripuddin Saripuddin, Sahidin Sahidin
oai:journal.umpr.ac.id:article/1325
2020-05-22T05:08:41Z
bjop:Clin-Comm-Pharm
The Role of Pharmacist in the Health Care System: Current Scenario in India
Nimesh, Saurabh
Pharmacovigilance
Education
Ethics
Graduate
Social
Pharmacy
Pharmacists are society's specialists on drugs. The Pharmacist of today is a drug-maker, drug-dispenser, drug-custodian, patient-counselor, drug-researcher, and drug-educator and above all an honest and patriotic citizen. The techno-proficient foundation of the drug expert gives him/her the certainty of providing services with a moral way to deal with the satisfaction of patients. The consecrated qualities are required to be cherished and professed by the pharmacist. Pharmacists assume a significant job in giving health care services, benefits by means of community pharmacy services in rural areas where physicians are not accessible or where physician services are unreasonably expensive for meeting the health care necessities. The paper at that point recognizes how pharmacists give expanded services, identifies key challenges and barriers, and suggests rules and regulations that could help secure open doors for pharmacists to play out an extended job.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-05-21
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
https://journal.umpr.ac.id/index.php/bjop/article/view/1325
10.33084/bjop.v3i2.1325
Borneo Journal of Pharmacy; Vol. 3 No. 2 (2020): Borneo Journal of Pharmacy; 84-89
2621-4814
10.33084/bjop.v3i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1325/1235
https://journal.umpr.ac.id/index.php/bjop/article/view/1325/1248
Copyright (c) 2020 Saurabh Nimesh
oai:journal.umpr.ac.id:article/1337
2020-05-22T05:08:40Z
bjop:Pharm-Phyto
Antioxidant Properties of Pyrus communis and Pyrus pyrifolia Peel Extracts
Patricia, Vinda Maharani
Syaputri, Fauzia Ningrum
Tugon, Titian Daru Asmara
Mardhatillah, Athina
Antioxidant
Peel extract
Pyrus communis
Pyrus pyrifolia
Phytochemistry
With the rise of global health awareness by embracing a healthy lifestyle and natural product consumption, the search for natural antioxidant sources has invited more research performed especially in fruits as a whole product or in its components, especially the ones that are usually discarded/not the mainly consumed component. Pyrus communis and Pyrus pyrifolia are two of the most popular species of pear fruits consumed in the world, and while there exist several studies about the antioxidant potential of its flesh, specific studies about the antioxidant properties of their peels are still lacking. To achieve an understanding of antioxidant properties of peel extract of P. communis and P. pyrifolia, several tests have been performed in controlled laboratory conditions to gauge phenolic and flavonoid contents through three different extraction measurements. This research has shown that peel extracts of both P. communis and P. pyrifolia contain natural antioxidants that are beneficial for health, with P. communis extracted with methanol having a higher concentration of antioxidant contents compared to P. pyrifolia.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-05-21
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
https://journal.umpr.ac.id/index.php/bjop/article/view/1337
10.33084/bjop.v3i2.1337
Borneo Journal of Pharmacy; Vol. 3 No. 2 (2020): Borneo Journal of Pharmacy; 64-70
2621-4814
10.33084/bjop.v3i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1337/1233
https://journal.umpr.ac.id/index.php/bjop/article/view/1337/1241
Copyright (c) 2020 Vinda Maharani Patricia, Fauzia Ningrum Syaputri, Titian Daru Asmara Tugon, Athina Mardhatillah
oai:journal.umpr.ac.id:article/1356
2020-05-22T05:08:39Z
bjop:Microbiology
Carbapenem Resistant Enterobacteriaceae in Africa
Gulumbe, Bashar Haruna
Ajibola, Olumide
Carbapenem
Antibiotic resistance
Enterobacteriaceae
Africa
Carbapenems are regarded as unique among the β-lactam antibiotics due to their broad spectrum of activity and ability to resist β-lactamase hydrolysis. Carbapenems are the only β-lactam antibiotics with efficacy in severe infections caused by extended-spectrum beta-lactamase (ESBL) producing bacteria. However, recent reports of carbapenem resistance particularly among members of Enterobacteriaceae that are responsible for diseases such as gastrointestinal infections, septicemia, pneumonia, meningitis, peritonitis as well as urinary tract infections, call for concerns. In Africa, the problem of carbapenem-resistant Enterobacteriaceae (CRE) is aggravated by factors such as the high rate of infections, poor diagnostic tools, sub-optimal disease surveillance, and abuse of antibiotics. Besides, the problem of CRE in Africa is understudied. This review distills available literature on the spread of CRE in Africa, CRE genes in circulation, and the need to pay attention to this emerging threat to lives in developing countries.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-05-21
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
https://journal.umpr.ac.id/index.php/bjop/article/view/1356
10.33084/bjop.v3i2.1356
Borneo Journal of Pharmacy; Vol. 3 No. 2 (2020): Borneo Journal of Pharmacy; 71-78
2621-4814
10.33084/bjop.v3i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1356/1231
https://journal.umpr.ac.id/index.php/bjop/article/view/1356/1246
Copyright (c) 2020 Bashar Haruna Gulumbe, Olumide Ajibola
oai:journal.umpr.ac.id:article/1359
2020-09-04T06:23:49Z
bjop:Clin-Comm-Pharm
Assessment of Drug Therapy Problems Among Type 2 Diabetes Patients with Hypertension Comorbidity in Indonesia
Julaeha, Julaeha
Fudjiati, Ery
Eff, Aprilita Rina Yanti
Diabetes Mellitus
Hypertension
Drug Therapy Problems
Type 2 Diabetes
Management Therapy
Clinical Pharmacy
Type 2 diabetes mellitus (T2DM) is a major chronic disease that affects a large number of people worldwide. Hypertension is a common disease comorbidity among T2DM patients, and often those patients received polypharmacy and complex treatment in long term duration. This condition may lead to an increased risk of drug therapy problems (DTPs). This study aimed to assess and determine potential drug therapy problems in type 2 diabetic patients with hypertension comorbidity. Retrospective cross-sectional design was conducted in a hospital setting, especially data sources from the prescription of ambulatory T2DM patients with hypertension. A total of 190 patients were studied. More than half of the participants were female (53.68%). The majority age range of participants was 50-59 years (46.84%). Almost all antidiabetic agents were prescribed as polypharmacy (73.16%). Metformin was the most antidiabetic agent prescribed as monotherapy and combination therapy (63.16%). Almost all antihypertensive agents were prescribed as polypharmacy (63.26%). Amlodipine was the most antihypertensive agent prescribed as monotherapy and combination therapy (34.74%). Among the study participants, 56.84% have at least one of DTPs. Adverse drug reaction was the most frequent (47.22%), followed by ineffective drug therapy (29.63%). Since the potential of DTPs in T2DM patients with hypertension comorbidity is relatively high, early identifying, resolving, and preventing drug therapy problems by the pharmacist is needed to achieve goals of treatment.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-08-31
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1359
10.33084/bjop.v3i3.1359
Borneo Journal of Pharmacy; Vol. 3 No. 3 (2020): Borneo Journal of Pharmacy; 190-198
2621-4814
10.33084/bjop.v3i3
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1359/1399
https://journal.umpr.ac.id/index.php/bjop/article/view/1359/1406
https://journal.umpr.ac.id/index.php/bjop/article/view/1359/1409
Copyright (c) 2020 Julaeha Julaeha, Ery Fudjiati, Aprilita Rina Yanti Eff
oai:journal.umpr.ac.id:article/1365
2020-09-04T06:23:48Z
bjop:Pharm-Tox
Phytochemical Screening and Anti-Hyperuricemia Activity Test In Vivo of Ethanolic Extract of Shallot (Allium cepa L.) Skin
Syahrina, Syahrina
Asfianti, Vivi
Gurning, Kasta
Iksen, Iksen
Hyperuricemia
Allopurinol
Potassium oxonate
Shallot
Shallot skin
Pharmacology
Uric acid is the final product of purine metabolism that will be excreted through urine, feces, and sweat. Excessive production of uric acid can cause hyperuricemia, known as gout. The skin of shallots (Allium cepa L.) is one of the household wastes that are very rarely used by the community. Ethanol extract of shallot skin (EESS) was tested for phytochemical screening and anti-hyperuricemia activity using potassium oxonate. Mice were divided into five groups (Allopurinol, Na-CMC, EESS 200 mg/kg BW, 300 mg/kg BW, and 400 mg/kg BW) and uric acid levels were observed at 2-hour intervals for six hours. Phytochemical screening shows that EESS has potential compounds in the treatment of gout. Tests to reduce uric acid levels showed that EESS has better potential than allopurinol at concentrations of 300 mg/kg BW and 400 mg/kg BW after six hours of induction in reducing uric acid levels.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-08-31
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1365
10.33084/bjop.v3i3.1365
Borneo Journal of Pharmacy; Vol. 3 No. 3 (2020): Borneo Journal of Pharmacy; 146-151
2621-4814
10.33084/bjop.v3i3
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1365/1383
https://journal.umpr.ac.id/index.php/bjop/article/view/1365/1401
https://journal.umpr.ac.id/index.php/bjop/article/view/1365/1407
Copyright (c) 2020 Syahrina Syahrina, Vivi Asfianti, Kasta Gurning, Iksen Iksen
oai:journal.umpr.ac.id:article/1394
2020-09-04T06:23:46Z
bjop:Pharm-Phyto
Phytochemicals, Nutritional Value, Antioxidant, and Anticoagulant Activity of Lactuca sativa L. Leaves and Stems
Mughrbi, Hanin Nafed
Auzi, Abdurazag Abdussalam
Maghrbi, Hamza
Lactuca sativa
DPPH
Activated Partial Thromboplastin Time
Anticoagulants
Prothrombin Time
Phytochemistry
The main ingredient in the daily salad dish is the leaves of Lactuca sativa, while the stems are usually discarded and not eaten. This study was conducted to compare the stems and leaves of two selected L. sativa varieties (L. sativa var. longifolia L. and L. sativa var. capitata L.) related to the preliminary phytochemical investigation, nutrient content, DPPH assay, and in vitro anticoagulant activity by determination of prothrombin time (PT) and activated partial thromboplastin time (aPTT). The findings revealed almost the same phytoconstituents in the leaves and stems of each variety, such as terpenoids, flavonoids, coumarins, and others. Exceptionally, tannins have only been detected in the leaves. Compared to the stems, the leaves of both varieties showed statistically significantly higher levels of raw protein and raw fat. For the DPPH assay, the leaves of both varieties have a statistically significantly higher antioxidant activity than the stems. The leaves and stem extract of the two selected varieties showed a significant prolongation of PT (P <0.05 vs. NS= 12:30 s). On the other hand, the aPTT test showed a significant increase in aPTT (P <0.05 vs. NS = 32:44 s) in the stem extract of both varieties, whereas there was no statistically significant increase in aPTT in the leaves of both varieties. Both parts of each variety have a diversity of phytochemicals and nutrients. The leaves of both varieties have a higher antioxidant activity than the stems. While the stems had higher anticoagulant activity than the leaves.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-08-31
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1394
10.33084/bjop.v3i3.1394
Borneo Journal of Pharmacy; Vol. 3 No. 3 (2020): Borneo Journal of Pharmacy; 152-161
2621-4814
10.33084/bjop.v3i3
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1394/1384
https://journal.umpr.ac.id/index.php/bjop/article/view/1394/1402
https://journal.umpr.ac.id/index.php/bjop/article/view/1394/1408
Copyright (c) 2020 Hanin Nafed Mughrbi, Abdurazag Abdussalam Auzi, Hamza Maghrbi
oai:journal.umpr.ac.id:article/1397
2020-09-04T06:18:59Z
bjop:spc
Global Pandemic Conditions and List of Possible Medications and Vaccines for the Treatment of COVID-19: A Review
Mukim, Mohammad
Kabra, Atul
Devi, Siwani
Chaturvedi, Mohit
Patel, Rakesh
Chloroquine
China
COVID-19
Lopinavir
SARS-CoV-2
Teicoplanin
Pharmacology
At the end of December 2019, a novel coronavirus was identified which caused severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with a disease known as coronavirus disease 2019 (COVID-19). The virus first originated in the city of Wuhan in China, causing symptoms such as pneumonic plague, which began in the Wuhan and then spread throughout the world with high transmission efficiency. Special precautions and care are needed such as leaving the public area, covering your mouth with a mask, not shaking hands, washing hands, and sanitation from time to time. Infection due to SARS-CoV-2 shows several symptoms, one of which is very often the patient shows difficulty breathing. Currently, COVID-19 has been declared a global pandemic and has almost attacked all countries in the world, including in India which has one of the largest human populations in the entire world. One of the challenges in handling COVID-19 is the unavailability of drugs or special vaccines to treat the disease, so clinical practitioners and academics are currently testing various drugs to see how they affect the COVID-19 patients. Some of the drugs tested provide effective mechanisms against SARS-CoV-2, such as chloroquine, remdesivir, lopinavir, and vaccines under development. These drugs are still being tested and are now at the forefront to combat the effects of SARS-CoV-2 infection. This review article will discuss all kinds of ins and outs of SARS-CoV-2 and COVID-19, including the transmission method, how to prevent it, as well as various drugs and vaccines currently used in handling COVID-19.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-06-22
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
text
application/pdf
application/xml
https://journal.umpr.ac.id/index.php/bjop/article/view/1397
10.33084/bjop.v3iSpecial-1.1397
Borneo Journal of Pharmacy; Vol. 3 No. Special-1 (2020): Borneo Journal of Pharmacy: COVID-19; 90-102
2621-4814
10.33084/bjop.v3iSpecial-1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1397/1281
https://journal.umpr.ac.id/index.php/bjop/article/view/1397/1302
Copyright (c) 2020 Mohammad Mukim, Atul Kabra, Siwani Devi, Mohit Chaturvedi, Rakesh Patel
oai:journal.umpr.ac.id:article/1409
2020-05-22T05:08:38Z
bjop:Editorial
Cover, Content, and Editorial Note from Borneo J Pharm Vol. 3 No. 2 May 2020
Borneo J Pharm, Chief Editor of
Borneo Journal of Pharmacy
Alhamdulillahirabbil ‘alamin. The next edition of Borneo Journal of Pharmacy (Borneo J Pharm), has been published in May 2020. Starting from this edition, Borneo J Pharm increases the frequency of publishing four times a year. This change aims to improve the circulation of the best articles published by Borneo J Pharm. Also, starting from this edition, Borneo J Pharm applying the publish-as-you-go issue to present the title of the article that has been received as early as possible in order to increase the chances of readability and quotation of articles in Borneo J Pharm. This edition contains six articles consisting of Pharmacology-Toxicology, Pharmacognosy-Phytochemistry, Microbiology Pharmacy, and Clinical-Community Pharmacy. This edition includes writings from four countries including Indonesia, India, Nigeria, and The Gambia. The authors come from several institutions, including Shri Gopichand College of Pharmacy, Universitas Halu Oleo, Universitas Airlangga, Sekolah Tinggi Ilmu Kesehatan Borneo Lestari, Universitas Muhammadiyah Bandung, Universitas Jenderal Achmad Yani, Akademi Farmasi Surabaya, Federal University Birnin-Kebbi, and London School of Hygiene and Tropical Medicine, Gambia. Editorial boards are fully aware that there is still room for improvement in this edition, hence with all humility willing to accept constructive suggestions and feedback for improvements to the publication for the next editions. The editorial board would like to thank all editors and reviewers, and contributors of the scientific articles who have provided the repertoire in this issue. We hope that all parties, especially the contributors of the articles, could re-participate for the publication in the next edition on August 2020.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-05-21
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Editorial Notes
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1409
10.33084/bjop.v3i2.1409
Borneo Journal of Pharmacy; Vol. 3 No. 2 (2020): Borneo Journal of Pharmacy
2621-4814
10.33084/bjop.v3i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1409/1236
oai:journal.umpr.ac.id:article/1411
2022-12-17T14:09:42Z
bjop:Pharmaceut
Formulation and Evaluation of Natural Gel Containing Ethanolic Extract of Pandanus amaryllifolius R. Using Various Gelling Agents
Forestryana, Dyera
Hayati, Annisa
Putri, Aristha Novyra
Pandan leaves
Release kinetics
Gels
Gelling agents
Wound Healing
Pharmacy
Ethanol extract of Pandanus amaryllifolius leaves contains quercetin has anti-inflammatory properties. The gel dosage form is very appropriate for wound healing therapy because it gives a cold sensation to the skin. This study aims to formulate a P. amaryllifolius gel by variation of a gelling agent to compare the effect of a natural gelling agent, semi-synthetic gelling agent, and synthetic gelling agent on the physical characteristics of the gel. The gel formulation was made in three formulas. Evaluations include organoleptic, homogeneity, spreadability, adhesion, pH, and viscosity. The optimum gel formula was tested for release study using a dissolution apparatus 5. Determination of release kinetics model using the kinetics approach of zero-order, first-order, Higuchi, and Korsmeyer-Peppas. The organoleptic shows the gel's dark green color, P. amaryllifolius aromas, and good homogeneity. The gel formulas had pH values that matched the physical quality criteria of the gel. Data obtained for the spreadability test for F1, F2, and F3 were 12.16, 14.66, and 10.75 g.cm/sec, respectively. The F1, F2, and F3 adhesion test results were 11.66, 10, and 47.33, respectively. The viscosity of F1 was 15750 cps, F2 was 4807 cps, and F3 was 19380 cps. This study concludes that the optimum formula is obtained from the gelling agent of Na-CMC as a gelling agent. The number of quercetins released from F2 was 42.76%, and the release kinetics model followed the kinetics of Higuchi.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2022-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
text/xml
https://journal.umpr.ac.id/index.php/bjop/article/view/1411
10.33084/bjop.v5i4.1411
Borneo Journal of Pharmacy; Vol. 5 No. 4 (2022): Borneo Journal of Pharmacy; 345-356
2621-4814
10.33084/bjop.v5i4
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1411/2824
https://journal.umpr.ac.id/index.php/bjop/article/view/1411/2988
Copyright (c) 2022 Dyera Forestryana, Annisa Hayati, Aristha Novyra Putri
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/1412
2020-09-04T06:18:57Z
bjop:spc
Review on COVID-19: Rise of SARS-CoV-2 Pandemic Outbreak
Bala, Vidhan Chand
Kumar, Punet
COVID-19
coronavirus
2019-nCoV
SARS-CoV
MERS-CoV
SARS-Cov-2
Initially recognized of COVID-19 within the world in 2019, the World Health Organization situational report from May 22nd, 2020, globally, there is a complete of 5,204,508 confirmed cases, with 212 countries being affected by the novel coronavirus. 2019 novel coronavirus (SARS-CoV-2) is that the seventh member of the family of coronaviruses is enveloped viruses with a positive sense, single-stranded RNA genome. The SARS-CoV-2 may be a β-CoV of group 2B there is 70% comparability in genetic sequence to SARS-CoV. The source of the new coronavirus infection has been resolved as bats. With whole-genome sequences of SARS-CoV-2 is 96% comparatively at the whole-genome level to a bat coronavirus. Mechanisms of transmission are concluded to incorporate contact, droplet, and possibly airborne under certain circumstances supported ancient experiences associated with SARS-CoV outbreaks. Although antiretroviral therapy is being widely used everywhere the globe for such patents, effects at finding a SARS-CoV vaccine haven’t succeeded so far.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-06-22
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
text
application/pdf
application/xml
https://journal.umpr.ac.id/index.php/bjop/article/view/1412
10.33084/bjop.v3iSpecial-1.1412
Borneo Journal of Pharmacy; Vol. 3 No. Special-1 (2020): Borneo Journal of Pharmacy: COVID-19; 103-120
2621-4814
10.33084/bjop.v3iSpecial-1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1412/1282
https://journal.umpr.ac.id/index.php/bjop/article/view/1412/1303
Copyright (c) 2020 Vidhan Chand Bala, Punet Kumar
oai:journal.umpr.ac.id:article/1413
2020-09-04T06:18:55Z
bjop:spc
Preliminary Survey on Knowledge, Attitudes, and Practices about the COVID-19 Pandemic among Residents in North Central Nigeria
Ehoche, Elijah Edache
Adejoh, Johnson
Idoko, Joseph
Madu, Chijioke
COVID-19
Knowledge
Practice
North Central Nigeria
COVID-19
A preliminary survey on the knowledge, attitude, and practice of the COVID-19 pandemic among residence in North Central Nigeria, was conducted. An anonymous electronic network sampling survey designed by e-survey was employed. The result showed that on the level of knowledge and practice, 76.83% opined that people may be sick for 1-14 days without developing the symptoms. On the viral transmission, 94.41% agreed that the transmission of the virus can be through direct contact with contaminated surfaces through eyes, nose, and mouth, as well as 78.35%, responded that the virus doesn't penetrate the skin. More so 92.04% of the respondents showed that older and sick people are more vulnerable to the disease with 98.86% showing that the most common symptoms may include fever, tiredness, dry cough, and sometimes difficulty in breathing. Only 24.43% asserted that COVID-19 cannot be transmitted through social gatherings, going put often, making direct physical contact with people. Meanwhile, 21.02% showed COVID-19 is a punishment for immoral behavior. On the rate of the outbreak, 94.32% said it is scary. Only 55.11% asserted approval of the control approach by the government. However, 82.29% would agree with the response of the masses to government measures to control the spread. On the way forward, 98.87% advised the need for more research and 87.08% would approve of vaccination against the disease. This implies that the respondents have a good level of knowledge and practice about COVID-19 and necessary adjustments are needed to control or manage the spread of the pandemic.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-06-22
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1413
10.33084/bjop.v3iSpecial-1.1413
Borneo Journal of Pharmacy; Vol. 3 No. Special-1 (2020): Borneo Journal of Pharmacy: COVID-19; 121-129
2621-4814
10.33084/bjop.v3iSpecial-1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1413/1283
https://journal.umpr.ac.id/index.php/bjop/article/view/1413/1304
https://journal.umpr.ac.id/index.php/bjop/article/view/1413/1284
Copyright (c) 2020 Elijah Edache Ehoche, Johnson Adejoh, Joseph Idoko, Chijioke Madu
oai:journal.umpr.ac.id:article/1415
2020-09-04T12:20:36Z
bjop:Nat-Pro-Dev
Advantages of Herbal Over Allopathic Medicine in the Management of Kidney and Urinary Stones Disease
Nimesh, Saurabh
Ashwlayan, Vrish Dhwaj
Rani, Rubi
Prakash, Om
Hyperoxaluria
Uric acid
Ayurveda
Allopurinol
Xanthium strumarium
Pharmacology
Kidney and urinary stone disease (Nephrolithiasis and urolithiasis) are the condition where urinary stones or calculi are formed in the urinary tract. The problem of urinary stones is very ancient; these stones are found in all parts of the urinary tract, kidney, ureters, and the urinary bladder and may vary considerably in size. It is a common disease estimated to occur in approximately 12% of the population, with a recurrence rate of 70-81% in males and 47-60% in females. The treatment of kidney and urinary stone diseases such as a western (allopathy) medicine and surgery is now in trends. However, most people preferred plant-based (herbal) therapy because of the overuse of allopathic drugs, which results in a higher incidence rate of adverse or severe side effects. Therefore, people every year turn to herbal therapy because they believe plant-based medicine is free from undesirable side effects, although herbal medicines are generally considered to be safe and effective. In the present article, an attempt has been made to emphasize an herbal therapy is better than allopathic therapy for the management of the kidney and urinary stone disease.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-08-31
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1415
10.33084/bjop.v3i3.1415
Borneo Journal of Pharmacy; Vol. 3 No. 3 (2020): Borneo Journal of Pharmacy; 179-189
2621-4814
10.33084/bjop.v3i3
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1415/1398
https://journal.umpr.ac.id/index.php/bjop/article/view/1415/1405
https://journal.umpr.ac.id/index.php/bjop/article/view/1415/1412
Copyright (c) 2020 Saurabh Nimesh, Vrish Dhwaj Ashwlayan, Rubi Rani, Om Prakash
oai:journal.umpr.ac.id:article/1428
2020-09-04T06:18:47Z
bjop:spc
Novel Coronavirus: A Newly Arranged Mini-Review
Devi, Siwani
Tripathi, Kishan
Mukim, Mohammad
Jain, Vidhi
Ahmad, Nesar
Hasan, Noorul
Singh, Prashant Kumar
Khalid, Mohammad
COVID-19
Coronavirus
SARS-CoV-2
COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which was originally known as a virus that infects animals and rarely can be transmitted to humans in large populations, is now transformed into one of the most feared pandemics causes worldwide. Infection by a virus that is officially known as COVID-19 has caused global concern mainly due to the number of deaths caused. Since it was first reported in Wuhan, China in December 2019, now COVID-19 has spread to almost all parts of the world with a very rapid spread rate. The main symptom of this infection is a respiratory disease accompanied by other symptoms that resemble flu-like illness. Everyone can suffer from COVID-19, but the elderly, toddlers, pregnant women, and people with certain diseases and disorders of the immune system show more severe symptoms. The disease is transmitted through inhalation or contact with droplets, where the incubation period ranges from 2 to 14 days. Until now, specific therapy to treat COVID-19 has not been found, with preventive measures taken to control its spread. In this mini-review, we will explain important information related to COVID-19.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-06-22
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
text
application/pdf
application/xml
https://journal.umpr.ac.id/index.php/bjop/article/view/1428
10.33084/bjop.v3iSpecial-1.1428
Borneo Journal of Pharmacy; Vol. 3 No. Special-1 (2020): Borneo Journal of Pharmacy: COVID-19; 130-135
2621-4814
10.33084/bjop.v3iSpecial-1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1428/1289
https://journal.umpr.ac.id/index.php/bjop/article/view/1428/1305
Copyright (c) 2020 Siwani Devi, Kishan Tripathi, Mohammad Mukim, Vidhi Jain, Nesar Ahmad, Noorul Hasan, Prashant Kumar Singh, Mohammad Khalid
oai:journal.umpr.ac.id:article/1429
2020-09-04T06:18:52Z
bjop:spc
Coronavirus-SARS-CoV-2: Biology and Problems in rRT-PCR Detection
Moeis, Maelita Ramdani
Rahayu, Anis Puji
Ihsani, Nisa
Pertiwi, Wulan
COVID-19
SARS-CoV-2
rRT-PCR
Detection
False Results
COVID-19
Coronavirus disease 2019 (COVID-19) first appeared in China in December 2019 and was declared a pandemic by the World Health Organization. COVID-19 is caused by Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2), a new virus previously unknown to humans. Here we look at what is known about this virus, the main method for detecting the presence of this virus in a person who is used as a golden standard, and the problems that could arise in this detection method. Understanding the biology of the virus and the strengths and weaknesses of the detection method are important for patient management and for overcoming the pandemic.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-06-22
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
text
application/pdf
application/xml
https://journal.umpr.ac.id/index.php/bjop/article/view/1429
10.33084/bjop.v3iSpecial-1.1429
Borneo Journal of Pharmacy; Vol. 3 No. Special-1 (2020): Borneo Journal of Pharmacy: COVID-19; 136-145
2621-4814
10.33084/bjop.v3iSpecial-1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1429/1298
https://journal.umpr.ac.id/index.php/bjop/article/view/1429/1306
Copyright (c) 2020 Maelita Ramdani Moeis, Anis Puji Rahayu, Nisa Ihsani, Wulan Pertiwi
oai:journal.umpr.ac.id:article/1443
2021-05-20T02:39:24Z
bjop:Pharm-Phyto
Phytochemical and Cytotoxic Test of Durio kutejensis Root Bark on MCF-7 Cells
Priyadi, Muhammad
Haryoto, Haryoto
Anggraeni, Amaliyah Dina
Khong, Heng Yen
Phytochemical
Cytotoxic Test
Durio kutejensis
MCF7 cell
Phytochemistry
Durio kutejensis has known potential as herbal medicine in Kalimantan. Many things can be explored from D. kutejensis related pharmacological activity in every part of the plant included root bark. This study investigated the phytochemical content with a qualitative test and tested cytotoxic activities of D. kutejensis root bark on MCF-7 cell lines. Cytotoxic activity tested on MCF-7 cells with MTT assay method. The result showed that D. kutejensis root bark contains flavonoid, tannin, terpenoid, phenol, and saponin. IC50 value for ethanol extracts of root bark, n-hexane fractions, ethyl acetate fractions, and doxorubicin on MCF-7 cells were 761.29; 280.5; 207.08; and 0.25 μg/mL, respectively. In conclusion, D. kutejensis root bark has some secondary metabolites but no cytotoxic activity on MCF-7 cells. Further research is needed to explore the anticancer activity of secondary metabolites on some other cancer cells and other pharmacological activities.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2021-02-28
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1443
10.33084/bjop.v4i1.1443
Borneo Journal of Pharmacy; Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy; 1-5
2621-4814
10.33084/bjop.v4i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1443/1597
https://journal.umpr.ac.id/index.php/bjop/article/view/1443/1667
https://journal.umpr.ac.id/index.php/bjop/article/view/1443/1668
Copyright (c) 2021 Muhammad Priyadi, Haryoto Haryoto, Amaliyah Dina Anggraeni, Heng Yen Khong
oai:journal.umpr.ac.id:article/1480
2020-09-04T06:18:51Z
bjop:Editorial
Cover, Content, and Editorial Note from Borneo J Pharm Vol. 3 Special Issue 1 June 2020
Borneo J Pharm, Chief Editor of
Borneo Journal of Pharmacy
COVID-19 is currently the most researched topic worldwide. Apart from the effects that are caused by such a massive, also because the most effective therapies to treat it has still not been found. Therefore, researchers around the world seem to compete with time to research to find ways to overcome the global pandemic. Seeing this trend, the Borneo Journal of Pharmacy (Borneo J Pharm) does not want to be left behind to participate in sharing information related to COVID-19, and Alhamdulillahirabbil 'alamin, in the middle of 2020 Borneo J Pharm published its first Special Issue with the related Research and Review theme of COVID-19. This edition contains five articles both research articles and reviews from domestic and foreign authors. The authors came from four countries consisting of Indonesia, India, Saudi Arabia, and Nigeria. The authors also come from several institutions, including Kota College of Pharmacy, Dr. A.P.J. Abdul Kalam University, Raffles University, Oxford College of Pharmacy, Shri Gopichand College of Pharmacy, Federal University of Technology Minna, University of Abuja, Benue State Polytechnic, Rahul Sankrityayan College of Pharmacy, Jamia Hamdard, Chhatrapati Shahu Ji Maharaj University, Prince Sattam bin Abdulaziz University, and Universitas Muhammadiyah Bandung
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-06-22
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Editorial Notes
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1480
10.33084/bjop.v3iSpecial-1.1480
Borneo Journal of Pharmacy; Vol. 3 No. Special-1 (2020): Borneo Journal of Pharmacy: COVID-19
2621-4814
10.33084/bjop.v3iSpecial-1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1480/1301
oai:journal.umpr.ac.id:article/1500
2020-12-08T00:50:01Z
bjop:Nat-Pro-Dev
Determination of Antiradical Activity, Total Phenolic, and Total Flavonoid Contents of Extracts and Fractions of Langsat (Lansium domesticum Coor.) Seeds
Yamin, Yamin
Ruslin, Ruslin
Sabarudin, Sabarudin
Sida, Nurramadhani A
Kasmawati, Henny
Diman, La Ode Muhammad
Antiradical
DPPH
Total flavonoid content
Lansium domesticum
Total phenolic content
Antiradical
Lansium domesticum Coor. is a fruit species from the Meliaceae family, which is a tropical plant native to Southeast Asia. Local citizens call it langsat, longkong, or duku and have used it as traditional medicine. The seeds of L. domesticum are used as a fever medicine, its bark is used to treat scorpion sting, and its leaves are used to repel mosquitoes. Because of its various uses, it is necessary to explore the antiradical potential of L. domesticum seeds. This study aims to determine the antiradical potential of L. domesticum seeds extract and fractions by using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method and to discover compounds that act as antiradical. Lansium domesticum seed powder was macerated with methanol, and then the extract was concentrated using a rotary evaporator and fractionated by n-hexane and ethyl acetate. The antiradical assay was conducted on extract and fractions by using DPPH radicals. Phenolic and flavonoid contents from extract and fractions were also tested. The ethyl acetate fraction obtained strong antiradical potential with an IC50 value of 8.938 ± 0.031 µg/mL. Total phenolic and flavonoid contents of ethyl acetate fraction were higher with values of 58.25 ± 0.501 mgGAE/g sample and 75.123 ± 0.175 mgQE/g sample, respectively. Correlation of phenolic and flavonoid contents, which inhibited radicals had R2 values of 0.9182 and 0.7658. Ethyl acetate fraction of L. domesticum seeds had very strong antiradical activity. Further isolation is expected to be conducted to discover which compounds are the most responsible as antiradical.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1500
10.33084/bjop.v3i4.1500
Borneo Journal of Pharmacy; Vol. 3 No. 4 (2020): Borneo Journal of Pharmacy; 249-256
2621-4814
10.33084/bjop.v3i4
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1500/1496
https://journal.umpr.ac.id/index.php/bjop/article/view/1500/1785
https://journal.umpr.ac.id/index.php/bjop/article/view/1500/1786
Copyright (c) 2020 Yamin Yamin, Ruslin Ruslin, Sabarudin Sabarudin, Nurramadhani A Sida, Henny Kasmawati, La Ode Muhammad Diman
oai:journal.umpr.ac.id:article/1524
2020-09-04T06:23:42Z
bjop:Pharm-Phyto
Microscopical Investigation of Sideritis taurica
Serebryanaya, Fatima Kazbekovna
Konovalova, Irina
Morphological and Anatomical Research
Lamiaceae
Diagnostic signs
anatomical structure
Stem
Flower
Sideritis taurica
Pharmacognosy
This research presents the results of the morphological-anatomical study of grass organs above ground (leaves, stems, and flowers) from Sideritis taurica Steph. ex Willd. from the Lamiaceae family. The range of distribution of this species covers Eastern Europe, including Crimea, Caucasus. This plant is commonly found as an ornamental plant and grows in the southern and central regions of Russia. The purpose of this study is the anatomical and morphological study of the vegetative organs of S. taurica and the formation of diagnostic signs for reliable plant identification. The research material used was S. taurica herbicide samples collected in Crimea on the slopes of Mount Ay-Petri. Plant material is fixed in the glycerin : water system in a ratio of 1 : 1. Cross-section of stems and leaves is carried out using blades. The study was conducted with the morphological-anatomical method. The results obtained indicate the anatomical structure of the lamina, stem, and flower of the plant that has been studied. Anomocytic types of stomatal devices, unicellular and multicellular trichomes, located on the upper and lower sides of the leaf, as well as on the corolla stem and epidermis, have been discovered. The study carried out is part of the S. taurica complex pharmacognostic study.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-08-31
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1524
10.33084/bjop.v3i3.1524
Borneo Journal of Pharmacy; Vol. 3 No. 3 (2020): Borneo Journal of Pharmacy; 162-169
2621-4814
10.33084/bjop.v3i3
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1524/1396
https://journal.umpr.ac.id/index.php/bjop/article/view/1524/1403
https://journal.umpr.ac.id/index.php/bjop/article/view/1524/1411
Copyright (c) 2020 Fatima Kazbekovna Serebryanaya, Irina Konovalova
oai:journal.umpr.ac.id:article/1530
2020-09-04T06:23:40Z
bjop:Microbiology
Antibiotics Resistance Pattern of Coliform Bacteria Isolated from Slaughterhouse Wastewater in Jega Town, Kebbi State, Nigeria
Aliero, Adamu Almustapha
Jega, Namadina Hassan
Bagudo, Ahmad Ibrahim
Manga, Sahabi Sule
Hussaini, Kabiru
Antibiotics
Coliform bacteria
Wastewater
Jega
Slaughterhouse
Resistant
Microbiology
Wastewater is an essential reservoir of pathogenic bacteria, which include resistant strains. This study determined the antibiotics resistance pattern of Coliform bacteria isolated from slaughterhouse wastewater in Jega local government. Five different samples of wastewater from different locations of a slaughterhouse were collected using standard sample collection techniques. Coliform bacteria were isolated using the standard microbiological method. The total bacterial count was determined using plate count agar. Suspected coliforms were identified based on morphological and biochemical tests. Antimicrobial susceptibility testing was carried out using the standard disc diffusion method. The highest bacterial count (8.4x102 CFU/ml) was observed from the wastewater collection point, and the lowest bacterial (1.2x102 CFU/ml) count from the slaughtering point. Three Gram-negative bacteria, Escherichia coli, Pseudomonas aeruginosa, and Enterobacter aerogenes, were identified. Escherichia coli was the most frequently isolated in slaughterhouse wastewater 39 (45.8%). Among the antibiotics tested against isolated bacteria, Septrin was the most resistant antibiotics recorded against E. coli and E. aerogenes with 84.61% and 88.89% resistant, respectively. Pseudomonas aeruginosa was found to show higher resistance to Chloramphenicol and Septrin with 84.21% resistance each. The occurrence of antibiotic-resistant bacteria from slaughterhouse wastewater showed the risks associated with antimicrobial drug resistance transferred from food-producing animals to humans. Management concerns, such as local government health officers and community development officers, should increase the sensitization of slaughterhouse workers by organizing conferences or conducting radio talk to educates these slaughterhouse workers on the treatment of slaughterhouse wastewater and health risk associated with antimicrobial-drug resistance transferred from animals to humans.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-08-31
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1530
10.33084/bjop.v3i3.1530
Borneo Journal of Pharmacy; Vol. 3 No. 3 (2020): Borneo Journal of Pharmacy; 170-178
2621-4814
10.33084/bjop.v3i3
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1530/1397
https://journal.umpr.ac.id/index.php/bjop/article/view/1530/1404
https://journal.umpr.ac.id/index.php/bjop/article/view/1530/1410
Copyright (c) 2020 Adamu Almustapha Aliero, Namadina Hassan Jega, Ahmad Ibrahim Bagudo, Sahabi Sule Manga, Kabiru Hussaini
oai:journal.umpr.ac.id:article/1541
2020-12-08T00:49:58Z
bjop:Pharm-Phyto
Pharmacognostic Study and Antioxidant Activity of Mundar (Garcinia forbesii King.) leaves from Banua Botanical Gardens of South Kalimantan
Sutomo, Sutomo
Kamali, Dina Noor
Arnida, Arnida
Normaidah, Normaidah
Sriyono, Agung
Garcinia forbesii King.
Mundar
Leaves
Pharmacognostic study
Antioxidant
Pharmacognosy-Phytochemistry
Mundar (Garcinia forbesii King.) is a plant from South Kalimantan. This plant has chemical contents that have potential as medicine. The purpose of this study is to provide a pharmacognostic picture of a specific, nonspecific and determine the antioxidant activity of G. forbesii leaves. Specific parameters include organoleptic, microscopic testing, thin-layer chromatography profiles, and phytochemical screening. Nonspecific parameters include total ash content, acid insoluble ash content, drying loss, water-soluble extract content, and ethanol-soluble extract content. Antioxidant activity was determined by the DPPH method based on IC50 values. Specific parameter test results are green powder, characteristic odor, and sour taste. Microscopic tests showed stomata, upper epidermis, lower epidermis, cell walls, xylem, phloem, palisade tissue, spongy tissue, and cuticles. Garcinia forbesii leaves contain alkaloids, flavonoids, phenols, tannins, and steroids. The TLC profile showed good separation of polar eluents, and yellow spots appeared after spraying DPPH reagents. The non-specific parameter test is the total ash content of 6.52±0.1%; acid insoluble ash content 1.06±0.08%; drying shrinkage 6.43±0.38%; water-soluble extracts 34.3±0.3%; and ethanol-soluble extracts 23.47±0.35%. Ethanol extract of G. forbesii leaves has antioxidant activity with IC50 of 65.7 ppm. Pharmacognostic study fulfills the requirements, and G. forbesii leaves extract has strong antioxidant activity.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1541
10.33084/bjop.v3i4.1541
Borneo Journal of Pharmacy; Vol. 3 No. 4 (2020): Borneo Journal of Pharmacy; 209-215
2621-4814
10.33084/bjop.v3i4
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1541/1491
https://journal.umpr.ac.id/index.php/bjop/article/view/1541/1775
https://journal.umpr.ac.id/index.php/bjop/article/view/1541/1776
Copyright (c) 2020 Sutomo Sutomo, Dina Noor Kamali, Arnida Arnida, Normaidah Normaidah, Agung Sriyono
oai:journal.umpr.ac.id:article/1552
2020-12-08T00:49:55Z
bjop:Microbiology
Antibacterial Activity of Bandotan (Ageratum conyzoides L) Leaves Extracts Against Methicillin-Resistant Staphylococcus aureus
Maulidya, Selvira Anandia Intan
Nuari, Doni Anshar
Suryana, Shendi
Almarifah, Sumia
Ageratum conyzoides
MRSA
Antibacterial
Microbiology
Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of nosocomial infections throughout the world and can be life-threatening as well. This study aimed to determine the antibacterial activity of Bandotan (Ageratum conyzoides L) leaves ethanolic extract against MRSA's growth. Ageratum conyzoides leaves were extracted by ethanol and screened for their phytochemical constituent. Ethanolic extracts of A. conyzoides leaves were evaluated for their potential antibacterial activity using disc diffusion assay. The minimum inhibitory concentration (MIC) value was determined using the agar dilution method. Phytochemical screening shows that the extracts contain alkaloids, flavonoids, saponins, tannins, and steroids or triterpenoids. Ageratum conyzoides leaves extract shows a 25.1 mm inhibitory zone at 12.5% extract concentration with MIC value equivalents to 4.46 x 10-6 g of gentamicin. This study concludes that A. conyzoides leaves ethanolic extracts have potential antibacterial activity against MRSA.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1552
10.33084/bjop.v3i4.1552
Borneo Journal of Pharmacy; Vol. 3 No. 4 (2020): Borneo Journal of Pharmacy; 243-248
2621-4814
10.33084/bjop.v3i4
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1552/1495
https://journal.umpr.ac.id/index.php/bjop/article/view/1552/1783
https://journal.umpr.ac.id/index.php/bjop/article/view/1552/1784
Copyright (c) 2020 Selvira Anandia Intan Maulidya, Doni Anshar Nuari, Shendi Suryana, Sumia Almarifah
oai:journal.umpr.ac.id:article/1554
2023-05-25T03:53:13Z
bjop:Pharm-Phyto
Morphological and Micromorphological Investigations of Bidens frondosa L. from Flora of Krasnodar Region, Russia
Zinchenko, Vladimir
Serebryanaya, Fatima Kazbekovna
bootjack bur
Bidens frondosa
stomatal apparatus
trichomes
Pharmacognosy
Complex morphological and micromorphological studies have been made about bootjack bur (Bidens frondosa) growing on the territory of the Krasnodar region. The lamina is of dorsoventral type. The conduction system has fasciations, three closed collateral bundles, are present near the vein. The leaf is of amphistomatic type, stomatic apparats are present in a small amount. Anticlinical walls of the main cells of the epidermis are strongly flexuose. The lower epidermis if compared to the upper one has a large number of stomatic apparatus of anisocytic type. The trichomes are leggy, represented by multicellular hairs of different shapes and lengths. Micromorphological capabilities of bootjack bur’s transverse section of the caulis and leafstalk have been studied. Received micromorphological data is a fragment of complex pharmacognostic studies of the Bidens kind. For acquiring the anti-allergic medication in the future, it is necessary to make pharma-technological studies and come up with the necessary medical form in the shape of thick extract and also make pharmacological studies in acquiring this medical form.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2023-02-28
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1554
10.33084/bjop.v6i1.1554
Borneo Journal of Pharmacy; Vol. 6 No. 1 (2023): Borneo Journal of Pharmacy; 15-21
2621-4814
10.33084/bjop.v6i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1554/3104
Copyright (c) 2023 Vladimir Zinchenko, Fatima Kazbekovna Serebryanaya
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/1557
2021-05-20T02:39:24Z
bjop:Pharmaceut
Formulation and Evaluation of Solid Dispersion Chitosan Tablet from Whiteleg Shrimp (Litopenaeus vannamei) Using PVP K-30 As a Carriers
Imtihani, Hilya Nur
Thalib, Fitria Abbas
Permatasari, Silfiana Nisa
Tablet
Solid Dispersion
Chitosan
Whiteleg Shrimp
PVP K-30
Pharmacy
Whiteleg shrimp (Litopenaeus vannamei) on the market are processed or sold only to take part in the meat. The head, shell, and tail are thrown away without any prior processing. Underutilized waste causes environmental problems. An alternative to overcome this environmental disturbance phenomenon is to utilize shrimp shells containing chitin and subsequently transformed into chitosan that can be applied in various fields. Chitosan has poor solubility in water but high permeability; thus, improve bioavailability is accomplished by making solid dispersions. This study aims to formulate and evaluate the solid dispersion tablet using chitosan extract from L. vannamei as an active agent with PVP K-30 as a carrier. The formulation divided into three groups, that was F1 (chitosan : PVP K-30 = 1 : 1 solid dispersion), F2 (chitosan : PVP K-30 = 1 : 3 solid dispersion), and F3 (pure chitosan). The result of chitosan solid dispersion was molded into tablets by the direct compression method. The tablets were evaluated by weight and size uniformity, hardness, friability, and disintegration time. All the formulas by weight and size uniformity as well as disintegration time fulfill the requirements. The hardness of the tablets from F3 with 4,275 kg was the best from F1 and F2. By statistic analytical from weight uniformity, hardness and disintegration time give significant difference with sig. <0.05.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2021-02-28
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1557
10.33084/bjop.v4i1.1557
Borneo Journal of Pharmacy; Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy; 16-21
2621-4814
10.33084/bjop.v4i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1557/1599
https://journal.umpr.ac.id/index.php/bjop/article/view/1557/1672
https://journal.umpr.ac.id/index.php/bjop/article/view/1557/1673
Copyright (c) 2021 Hilya Nur Imtihani, Fitria Abbas Thalib, Silfiana Nisa Permatasari
oai:journal.umpr.ac.id:article/1569
2020-12-08T00:49:53Z
bjop:Pharm-Tox
Role of Cannabinoid Receptors in Psychological Disorder
Jha, Ambika Nand
Patel, Dhaval M
Endocannabinoid
Neurochemical
CB1 receptors
CB2 receptors
Anxiety
Alzheimer
Pharmacology
Cannabinoid receptors, located throughout the body, are part of the endocannabinoid system. Cannabinoid CB1 and CB2 receptors are G protein-coupled receptors present from the early stages of gestation, which is involved in various physiological processes, including appetite, pain-sensation, mood, and memory. Due to the lipophilic nature of cannabinoids, it was initially thought that these compounds exert several biological effects by disrupting the cell membrane nonspecifically. Recent biochemical and behavioral findings have demonstrated that blockade of CB1 receptors engenders antidepressant-like neurochemical changes (increases in extracellular levels of monoamines in cortical but not subcortical brain regions) and behavioral effects consistent with antidepressant/antistress activity. We aim to define various roles of cannabinoid receptors in modulating signaling pathways and association with several pathophysiological conditions.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1569
10.33084/bjop.v3i4.1569
Borneo Journal of Pharmacy; Vol. 3 No. 4 (2020): Borneo Journal of Pharmacy; 199-208
2621-4814
10.33084/bjop.v3i4
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1569/1490
https://journal.umpr.ac.id/index.php/bjop/article/view/1569/1773
https://journal.umpr.ac.id/index.php/bjop/article/view/1569/1774
Copyright (c) 2020 Ambika Nand Jha, Dhaval M Patel
oai:journal.umpr.ac.id:article/1575
2021-05-20T02:39:24Z
bjop:Clin-Comm-Pharm
Validation of Finnish Diabetes Risk Score Indonesia Version in Yogyakarta
Pertiwi, Putri
Perwitasari, Dyah Aryani
Satibi, Satibi
FINDRISC
Diabetes Mellitus
Reliability
Validity
Clinical Pharmacy
Diabetes mellitus (DM) has developed as a major public health problem in the world. It is estimated that around 50% of diabetics have not been diagnosed in Indonesia, and only two-thirds of those diagnosed are undergoing treatment. This condition must be prevented. The purpose of this study was to determine the validity and reliability of the Indonesian version of the Finnish Diabetes Risk Score (FINDRISC) as an instrument for predicting type 2 diabetes mellitus (T2DM). This study was an observational study with a cross-sectional design on 60 research subjects who were indigenous people of Yogyakarta who live in Yogyakarta, which can be proven by Identity Cards by the inclusion and exclusion criteria. Validity was tested by the validity of criteria by type while using the area under the receiver-operating curve (ROC-AUC). In contrast, reliability was tested by internal consistency using Cronbach's alpha. The results showed that as many as 14 people or 23.33% experienced uncontrolled fasting blood sugar and 15 people had a risk score of FINDRISC more than 10. Based on the ROC AUC analysis, the value of 0.935 (95% CI 0.865 1.00) with a cut-off point of 10 with the value of Sn = 85%, Sp = 95%, PPV = 85%, NPV = 95%, +LR = 5.66, and -LR = 0.15. Based on the reliability test, the Cronbach's alpha value of 0.727 was obtained. The FINDRISC questionnaire is categorized as valid and reliable so that it can be a screening tool for understanding.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2021-02-28
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1575
10.33084/bjop.v4i1.1575
Borneo Journal of Pharmacy; Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy; 57-67
2621-4814
10.33084/bjop.v4i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1575/1634
https://journal.umpr.ac.id/index.php/bjop/article/view/1575/1684
https://journal.umpr.ac.id/index.php/bjop/article/view/1575/1685
Copyright (c) 2021 Putri Pertiwi, Dyah Aryani Perwitasari, Satibi Satibi
oai:journal.umpr.ac.id:article/1578
2021-05-20T02:39:24Z
bjop:Nat-Pro-Dev
The Combination of Turmeric (Curcuma domestica) Rhizome Extract and Collagen in A Serum Formulation as an Antioxidant
Pratiwi, Denia
Sidoretno, Wahyu Margi
Aisah, Nur
Antioxidant
Collagen
DPPH
Serum
Tumeric
Natural Product
Turmeric (Curcuma domestica) has nutritious compounds called curcuminoids, which can be used as antioxidants. As an antioxidant, C. domestica extract can be used to ward off free radicals that damage collagen and elastin, a protein that keeps skin moist. This study aimed to determine the antioxidant activity of serum combined with collagen's addition using the DPPH method. The DPPH was made at a concentration of 80 μg/mL, and the absorption was read at a wavelength of 520 nm using a microplate rider. The study was conducted by making six formulations: F0, F1, F2, F3, F4, and F5 obtained the results of serum made from C. domestica extract that could inhibit free radicals and meet the physical evaluation test requirements of serum. Furthermore, the formula was made using only one active ingredient and only collagen to determine the extract or collagen's antioxidant activity. The results obtained indicate that collagen had a supporting role in adding antioxidant activity apart from its extract. The highest % inhibition value at F5 with 90.526% could ward off free radicals.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2021-02-28
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1578
10.33084/bjop.v4i1.1578
Borneo Journal of Pharmacy; Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy; 36-42
2621-4814
10.33084/bjop.v4i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1578/1602
https://journal.umpr.ac.id/index.php/bjop/article/view/1578/1678
https://journal.umpr.ac.id/index.php/bjop/article/view/1578/1679
Copyright (c) 2021 Denia Pratiwi, Wahyu Margi Sidoretno, Nur Aisah
oai:journal.umpr.ac.id:article/1579
2021-05-20T02:39:24Z
bjop:Clin-Comm-Pharm
Relationship Between Finnish Diabetic Risk Score (FINDRISC) with Health-Related Quality of Life in Yogyakarta
Wahyuningtyas, Ninda Sari
Perwitasari, Dyah Aryani
Satibi, Satibi
Type 2 Diabetes Mellitus
FINDRISC
Health-Related Quality of Life
Clinical Pharmacy
The number of people with type 2 diabetes mellitus (T2DM) in Indonesia increases every year. Control of the development of T2DM can be done by screening using Finnish Diabetic Risk Score (FINDRISC)-Indonesian. FINDRISC is a valid tool for estimating the risk of T2DM within the next 10 years. This condition can have a major impact on the estimated life span and quality of life in the future. The purpose of this research is to determine the relationship between FINDRISC-Indonesian and respondent characteristics with HRQoL from EuroQol-5 Dimension-5 Level (EQ-5D-5L) in Yogyakarta. The cross-sectional study was conducted on 125 respondents who met the inclusion criteria. The risk of developing T2DM was assessed using a validated and widely used FINDRISC (range 0-26 points), and quality of life was measured by the EQ-5D-5L instrument. Overall data were analyzed using the Pearson correlation test and Independent t-test. The results showed the domain of pain was the domain that reported most respondents' most problems (28.8%). The respondent's utility value was 0.958 ± 0.69, and the VAS value was 79.4 ± 0.7. There was a significant difference in utility value based on age characteristics (p = 0.013). There was a relationship between age and utility value (p = 0.006) and FINDRISC score with utility value (p = 0.003). This study concludes that a high FINDRISC score affects the quality of life, and older age has a lower quality of life.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2021-02-28
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1579
10.33084/bjop.v4i1.1579
Borneo Journal of Pharmacy; Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy; 68-77
2621-4814
10.33084/bjop.v4i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1579/1643
https://journal.umpr.ac.id/index.php/bjop/article/view/1579/1686
https://journal.umpr.ac.id/index.php/bjop/article/view/1579/1687
Copyright (c) 2021 Ninda Sari Wahyuningtyas, Dyah Aryani Perwitasari, Satibi Satibi
oai:journal.umpr.ac.id:article/1583
2020-12-08T00:49:50Z
bjop:Pharm-Phyto
Antioxidant, Antidiabetic, and Anti-obesity Potential of Ipomoea reptans Poir Leaves
Kurniawan, Hendrik
Dacamis, Ermenilda Sonia
Simamora, Adelina
Tobing, Priscilla Sari Dianauli Lumban
Hanapiah, Ali
Santoso, Adit Widodo
Anti-lipase
Anti-trypsin
α-Glucosidase inhibition
CuPRAC
Ipomoea reptans
Pharmacology
Ipomoea reptans Poir or kangkung is a popular leafy vegetable, a favorite to people in Asian countries. However, limited information is available on their bioactivities. In the present study, the antioxidant, antidiabetic, and anti-obesity potential of I. reptans leaves were investigated. Different fractions (ethanol, ethyl acetate, and hexane) of I. reptans leaves were evaluated for their scavenging activity on DPPH radicals, whereas their reducing potential was investigated by cupric reducing antioxidant capacity (CuPRAC), total antioxidant, and reducing power assays. The antidiabetic potential was investigated by their inhibition effect on α-glucosidase. Total phenolic and flavonoid contents of I. reptans leaves were solvent dependent. Ethyl acetate contained the highest phenolic content, followed by ethanol and hexane fractions. However, for flavonoid content, the order was ethanol > ethyl acetate > hexane. All fractions showed DPPH scavenging activity in a concentration-dependent manner, with activities weaker than standards ascorbic acid and BHT, in the order of ethanol > ethyl acetate > hexane. All fractions showed reducing capacity, but only hexane and ethanol fractions of I. reptans leaves showed inhibition on α-glucosidase, with hexane showed more potent inhibition compared to acarbose. The study also found that fractions of I. reptans inhibit lipase and trypsin, enzymes related to lipid metabolism. Findings in this study offer a prospect for I. reptans leaves as a functional food source for antioxidant, antidiabetic, and anti-obesity purposes.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1583
10.33084/bjop.v3i4.1583
Borneo Journal of Pharmacy; Vol. 3 No. 4 (2020): Borneo Journal of Pharmacy; 216-226
2621-4814
10.33084/bjop.v3i4
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1583/1492
https://journal.umpr.ac.id/index.php/bjop/article/view/1583/1778
https://journal.umpr.ac.id/index.php/bjop/article/view/1583/1777
Copyright (c) 2020 Hendrik Kurniawan, Ermenilda Sonia Dacamis, Adelina Simamora, Priscilla Sari Dianauli Lumban Tobing, Ali Hanapiah, Adit Widodo Santoso
oai:journal.umpr.ac.id:article/1589
2021-05-20T02:39:24Z
bjop:Nat-Pro-Dev
Formulation and Antibacterial Activity of Liquid Soap Containing Ketapang (Terminalia catappa L.) Leaves Extract
Dewi, Asiska Permata
Mardhiyani, Dini
Phytochemical screening
Antibacterial activity
Ketapang
Liquid soap
Physical evaluation
Natural Product
Ketapang (Terminalia catappa L.) is traditionally used by the community to treat the skin's infections caused by bacteria or fungi. In this study, T. catappa leaves extract was added to the liquid soap formula as an antibacterial. The purpose of this study was to determine the secondary metabolite compounds contained in T. catappa leaves extract, physical evaluation of the preparation, and antibacterial activity of liquid soap. Liquid soap formula was made with various concentrations of T. catappa leaves extract F0 (0%), F1 (1%), F2 (2%), and F3 (3%). The resulting soap was evaluated for organoleptic, pH, high foam, homogeneity, irritation, and its activity against Staphylococcus aureus, Staphylococcus epidermidis, and Escherichia coli using the disc diffusion method. The results showed that the T. catappa leaves extract contained flavonoids, tannins, saponins, and triterpenoids. The liquid soap formula F0 was clear, while F1, F2, and F3 had the characteristics of brown-dark brown, homogeneous, pH between 4.6-5.2, foam stability between 67-72%, which was not significantly different and stable after five minutes of testing, and it did not irritate the skin. Terminalia catappa leaves extracts liquid soap has antibacterial activity at a concentration of 1%, 2%, and 3%, with the largest inhibition zone diameter produced by S. aureus.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2021-02-28
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1589
10.33084/bjop.v4i1.1589
Borneo Journal of Pharmacy; Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy; 43-50
2621-4814
10.33084/bjop.v4i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1589/1603
https://journal.umpr.ac.id/index.php/bjop/article/view/1589/1680
https://journal.umpr.ac.id/index.php/bjop/article/view/1589/1681
Copyright (c) 2021 Asiska Permata Dewi, Dini Mardhiyani
oai:journal.umpr.ac.id:article/1592
2020-12-08T00:49:47Z
bjop:Analytical-Medicinal
Determination of Gossypol in Hamid and Bt (Seeni 1) Cottonseed Oil using Fourier Transform Infrared Spectroscopy
Abdelrahman, Samah AM
Yassin, Atif AA
Mirghani, Mohamed Elwathig Saeed
Bashir, Nabil HH
Bacillus thuringiensis
Cottonseed oil
FTIR spectroscopy
Gossypol
PLS
Analytical Pharmacy
This study was conducted to determine the gossypol content in Bt cottonseed (Seeni-1) oil by using Fourier Transform Infrared (FTIR) spectroscopy with an Attenuated Total Reflectance (ATR) element. The wavelengths used were selected by spiking refined, bleached deodorized palm oil (RBDPO) to gossypol concentrations of 0-5% and noting the regions of maximal absorbance. Absorbance values of the wavelength regions 3700-2400 & 1900-750 cm−1 and a partial least squares (PLS) method were used to derive calibration models for Hamid cottonseed oil, Seeni-1 cottonseed oil, and gossypol-spiked RBDPO. The coefficients of determination (R2) for the calibration models were computed for the FTIR spectroscopy results against those found by using the wet chemical method AOCS method Ba 8–78. The R2 was 0.8916, 0.9581, and 0.9374 for Hamid cottonseed oil, Seeni-1 cottonseed oil, and gossypol-spiked RBDPO, respectively. The standard error (SE) of the calibration was 0.053, 0.078, and 0.062, respectively. The calibration models were validated using the cross-validation technique within the same set of oil samples. The results of FTIR spectroscopy as a useful technique determining gossypol content in crude cottonseed oil showed that there is a significant difference (p <0.05) in the amount of gossypol content in Hamid and Bt Seeni-1 cottonseed oils.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1592
10.33084/bjop.v3i4.1592
Borneo Journal of Pharmacy; Vol. 3 No. 4 (2020): Borneo Journal of Pharmacy; 227-234
2621-4814
10.33084/bjop.v3i4
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1592/1493
https://journal.umpr.ac.id/index.php/bjop/article/view/1592/1780
https://journal.umpr.ac.id/index.php/bjop/article/view/1592/1779
Copyright (c) 2020 Samah AM Abdelrahman, Atif AA Yassin, Mohamed Elwathig Saeed Mirghani, Nabil HH Bashir
oai:journal.umpr.ac.id:article/1611
2020-12-08T00:49:38Z
bjop:Management
The Effect of Quality Service Towards Outpatients Satisfaction at Poasia Community Health Centre
Fristiohady, Adryan
Fitrawan, La Ode Muhammad
Pemudi, Yusniati Dwi
Ruslin, Ruslin
Ihsan, Sunandar
Ruslan, Ruslan
Purnama, La Ode Muhammad Julian
Service Quality
Patient Satisfaction
Gap
Management Pharmacy
The quality of outpatient services can be measured by the SERVQUAL model that considers five dimensions: tangibles, reliability, responsiveness, assurance, and empathy. This study aimed to look at the effect of service quality on outpatient satisfaction at the Poasia community health center's pharmacy. The subjects in this study were 33 outpatients. The analysis technique used is gap analysis to compare patients' expectations and reality, normality test data based on questionnaire patient satisfaction tested for validation. This study's results indicate the average value of the gap in the Poasia community health center's pharmacy, amounting to -0.44. From the value of the gap, the lowest gap value in the pharmacy center of Poasia is the place of service and the provision of inadequate drug information of -0.88. Based on the paired t-test where a significant value >0.05, Ho is rejected, and Ha accepted, which means a significant difference between the quality of service and patients' satisfaction in the Pharmacy of Puskesmas Poasia Kendari City. This study concludes that there is a significant gap between expectations and reality at the Poasia community health center's pharmacy.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1611
10.33084/bjop.v3i4.1611
Borneo Journal of Pharmacy; Vol. 3 No. 4 (2020): Borneo Journal of Pharmacy; 270-277
2621-4814
10.33084/bjop.v3i4
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1611/1501
https://journal.umpr.ac.id/index.php/bjop/article/view/1611/1791
https://journal.umpr.ac.id/index.php/bjop/article/view/1611/1792
Copyright (c) 2020 Adryan Fristiohady, La Ode Muhammad Fitrawan, Yusniati Dwi Pemudi, Ruslin Ruslin, Sunandar Ihsan, Ruslan Ruslan, La Ode Muhammad Julian Purnama
oai:journal.umpr.ac.id:article/1634
2020-12-08T00:49:45Z
bjop:Analytical-Medicinal
Activity Prediction of Bioactive Compounds Contained in Etlingera elatior Against the SARS-CoV-2 Main Protease: An In Silico Approach
Ramadhan, Dwi Syah Fitra
Fakih, Taufik Muhammad
Arfan, Arfan
Etlingera elatior
Main Protease
In Silico
COVID-19
Medicinal chemistry
The COVID-19 pandemic has become a serious problem today, with its prevalence increasing every day. The SARS-CoV-2 main protease (MPro) is a promising therapeutic target to inhibit replicating and spreading the virus that causes COVID-19. The compounds contained in the Etlingera elatior plant has the potential. This study aimed to examine the compounds' activity in E. elatior against SARS-CoV-2 MPro using in silico methods. A total of seven compounds contained in E. elatior were obtained from the Knapsack database. The compounds were then docked into the SARS-CoV-2 MPro receptor's active site with the PDB ID 6LU7. Afterward, the biological activities were predicted by the PASS prediction webserver. The molecular docking results showed that ergosterol peroxide and sitostenone had the best binding energy with -10.40 kcal/mol and -9.17 kcal/mol, respectively. The in silico PASS prediction showed it has potential as antiviral therapy. It concluded ergosterol peroxide and sitostenone has the potential as SARS-CoV-2 MPro inhibitor candidate.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1634
10.33084/bjop.v3i4.1634
Borneo Journal of Pharmacy; Vol. 3 No. 4 (2020): Borneo Journal of Pharmacy; 235-242
2621-4814
10.33084/bjop.v3i4
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1634/1494
https://journal.umpr.ac.id/index.php/bjop/article/view/1634/1782
https://journal.umpr.ac.id/index.php/bjop/article/view/1634/1781
Copyright (c) 2020 Dwi Syah Fitra Ramadhan, Taufik Muhammad Fakih, Arfan Arfan
oai:journal.umpr.ac.id:article/1644
2020-12-08T00:49:43Z
bjop:Nat-Pro-Dev
Potential of Frangipani (Plumeria alba) Leaves Extract as Ultra Violet Protection
Putra, I Gusti Ngurah Agung Windra Wartana
Arimbawa, Putu Eka
Artini, Ni Putu Rahayu
Frangipani
Extract
SPF
Sunscreen
UV
Phytochemistry
Sunlight is the source of life and energy. Besides that, sunlight also creates skin challenges such as sunburn, pigmentation, wrinkles, dermatitis, aging, and skin cancer. Natural sunscreen protection is a popular and preferred way among various regions of the world to reduce sunlight's harmful effect. This study aimed to determine the potential of frangipani (Plumeria alba) leaves extract in some concentrations as ultraviolet protection. Plumeria alba extract contained secondary metabolites such as flavonoids, phenolics, and alkaloids that function as impeding ultraviolet radiation. This study used an experimental method consisting of four treatments and six replications. This study shows that the extract with concentration 2500; 5000; 7500; and 10000 ppm consecutively have SPF value of 6.24; 12.00; 18.45; and 22.64. It can be concluded the P. alba leaves extract potential as ultraviolet protection.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1644
10.33084/bjop.v3i4.1644
Borneo Journal of Pharmacy; Vol. 3 No. 4 (2020): Borneo Journal of Pharmacy; 257-261
2621-4814
10.33084/bjop.v3i4
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1644/1497
https://journal.umpr.ac.id/index.php/bjop/article/view/1644/1787
https://journal.umpr.ac.id/index.php/bjop/article/view/1644/1788
Copyright (c) 2020 I Gusti Ngurah Agung Windra Wartana Putra, Putu Eka Arimbawa, Ni Putu Rahayu Artini
oai:journal.umpr.ac.id:article/1648
2020-09-04T06:23:39Z
bjop:Editorial
Cover, Content, and Editorial Note from Borneo J Pharm Vol. 3 No. 3 August 2020
Borneo J Pharm, Chief Editor of
Borneo Journal of Pharmacy
Alhamdulillahirabbil ‘Alamin. The next edition of Borneo Journal of Pharmacy (Borneo J Pharm), has been published in August 2020. Starting from this edition, Borneo J Pharm increases the frequency of publishing four times a year. This change aims to improve the circulation of the best articles published by Borneo J Pharm. Also, starting from this edition, Borneo J Pharm applying the publish-as-you-go issue to present the title of the article that has been received as early as possible in order to increase the chances of readability and quotation of articles in Borneo J Pharm. This edition contains six articles consisting of Pharmacology-Toxicology, Pharmacognosy-Phytochemistry, Microbiology Pharmacy, Natural Product Development, and Clinical-Community Pharmacy. This edition includes writings from five countries including Indonesia, India, Libya, Nigeria, and the Russian Federation. The authors come from several institutions, including Sekolah Tinggi Ilmu Kesehatan Senior Medan, University of Tripoli, National Centre for Diabetes and Endocrinology of Libya, Pyatigorsk Medical and Pharmaceutical Institute, Kebbi State University of Science and Technology of Aliero, Federal Medical Centre of Birnin-Kebbi, Shri Gopichand College of Pharmacy, Meerut Institute of Engineering and Technology, NKBR College of Pharmacy and Research Centre, Universitas 17 Agustus 1945 Jakarta, and Universitas Esa Unggul. The editorial board would like to thank all editors and reviewers, and contributors of the scientific articles who have provided the repertoire in this issue. We hope that all parties, especially the contributors of the articles, could re-participate for the publication in the next edition in November 2020.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-08-31
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Editorial Notes
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1648
10.33084/bjop.v3i3.1648
Borneo Journal of Pharmacy; Vol. 3 No. 3 (2020): Borneo Journal of Pharmacy
2621-4814
10.33084/bjop.v3i3
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1648/1400
oai:journal.umpr.ac.id:article/1660
2020-12-08T00:49:41Z
bjop:Clin-Comm-Pharm
Patient’s Compliance with Oral Antibiotics Treatments at Community Health Centers in Surabaya: A 20-KAO Questionnaire Development
Zulfa, Ilil Maidatuz
Handayani, Widya
Compliance
Antibiotics
Questionnaire
Community Health Centre
Community Pharmacy
The irrational and incompliance use of antibiotics has been correlated to bacterial resistance. Several methods evaluated patients' compliance with oral antibiotics have been conducted. However, a standard questionnaire for evaluating oral antibiotics compliance in Indonesian has not been developed yet. This study was conducted to record the content validity of the developed questionnaire called 20-KAO to assess compliance with oral antibiotics. The validity content test was conducted through six experts review using the Item Content Validity Index (I-CVI) and Scale-Content Validity Index (S-CVI). The experts were also requested to provide recommendations for each item, whether revisions or deletion. After the review process, the number of questions remains unchanged. A total of 19 out of 20 items had an I-CVI of 1.00, and S-CVI was calculated at 0.98. Therefore, 20 items of the 20-KAO questionnaire have excellent content validity. However, future construct validity and reliability test to analyze the responses of targeted respondents and the questionnaire's consistency are needed.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2020-11-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1660
10.33084/bjop.v3i4.1660
Borneo Journal of Pharmacy; Vol. 3 No. 4 (2020): Borneo Journal of Pharmacy; 262-269
2621-4814
10.33084/bjop.v3i4
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1660/1498
https://journal.umpr.ac.id/index.php/bjop/article/view/1660/1789
https://journal.umpr.ac.id/index.php/bjop/article/view/1660/1790
Copyright (c) 2020 Ilil Maidatuz Zulfa, Widya Handayani
oai:journal.umpr.ac.id:article/1665
2021-05-20T02:39:24Z
bjop:Analytical-Medicinal
GC-MS Analysis of Bioactive Compounds in Ethanol and Ethyl Acetate Fraction of Grapefruit (Citrus maxima L.) Rind
Zulbayu, La Ode Muhammad Andi
Lukitaningsih, Endang
Rumiyati, Rumiyati
C. maxima L.
GC-MS
Biological activities
Pharmacological activities
Analytical Pharmacy
The grapefruit (Citrus maxima L.) is a plant known by the public as a fruit consumed with various properties. This plant's use is well known, such as antioxidants, enhancing immunity, anti-aging, and antibacterial properties. This study aimed to identify and analyze the chemical compounds contained in C. maxima rind. The extract was obtained by the maceration method using ethanol and ethyl acetate as solvents. The fractionation process was carried out by Column Chromatography. Observation of thin-layer chromatography profiles with UV lamps 254 and 366 nm. Analysis of chemical compound components using GC-MS and data interpretation based on the Wiley 7.0 data library. The interpretation results of the EF1 fraction were β-copaen-4-α-ol, pentadecanoic acid, hexadecanoic acid, tetradecanoic acid, dotriacontane, osthol, 2H-1-benzopyran-2-one, 7-methoxy-8-(3-methyl-2-oxobutyl), furfural, 6-(2,3-Dihydroxy-3-methylbutyl)-7-methoxycoumarin, and 6-(iodomethyl)-5-methyl-4-oxahexanolide. The chemical compounds identified in EAF2 were 1-octadecanol, decane, tetracosane, hexacosane, and 1,2-benzenedicarboxylic acid (2-ethylhexyl) ester. It can be concluded that these compounds have biological and pharmacological activities.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2021-02-28
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1665
10.33084/bjop.v4i1.1665
Borneo Journal of Pharmacy; Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy; 29-35
2621-4814
10.33084/bjop.v4i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1665/1601
https://journal.umpr.ac.id/index.php/bjop/article/view/1665/1676
https://journal.umpr.ac.id/index.php/bjop/article/view/1665/1677
Copyright (c) 2021 La Ode Muhammad Andi Zulbayu, Endang Lukitaningsih, Rumiyati Rumiyati
oai:journal.umpr.ac.id:article/1675
2021-05-20T02:39:24Z
bjop:Pharmaceut
Antioxidant and UV Protection Activities of Squid (Loligo sp.) Ink Powder Lotions
Rahmasari, Dyah
Juwanti, Aulia
Pratiwi, Ima
Diana, Novia Zulfa
Nugraheni, Raditya Weka
Rakhma, Dita Nurlita
Antioxidant
DPPH
UV Protection
Squid Ink Powder
Pharmaceutical
Melanin is a pigment contains in human skin which role as a UV-absorbing agent. One of the exogenous melanins can be obtained from squid (Loligo sp.) ink. Squid ink melanin has potent free radical protection activities. This study aimed to determine the physicochemical, stability, antioxidant, and UV protection activities of squid ink powder lotions. Squid ink powders were obtained from the drying process using HCl 0.5M and stored in the climatic chamber. Antioxidant activity was conducted quantitatively using the DPPH (2,2-diphenyl-1-picrylhydrazil) scavenging method. The best result of the DPPH scavenging activity was 29.12±0.023%, shown from formula III. UV protection activity was conducted by observing erythema scores in animal skin, which exposure to UV. This preparation inhibits the effect of UV exposure. Squid ink powder lotions are potential as a sunscreen product.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2021-02-28
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1675
10.33084/bjop.v4i1.1675
Borneo Journal of Pharmacy; Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy; 22-28
2621-4814
10.33084/bjop.v4i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1675/1600
https://journal.umpr.ac.id/index.php/bjop/article/view/1675/1674
https://journal.umpr.ac.id/index.php/bjop/article/view/1675/1675
Copyright (c) 2021 Dyah Rahmasari, Aulia Juwanti, Ima Pratiwi, Novia Zulfa Diana, Raditya Weka Nugraheni, Dita Nurlita Rakhma
oai:journal.umpr.ac.id:article/1686
2021-05-20T02:39:24Z
bjop:Pharm-Phyto
Total Phenolic and Flavonoid Content, Antioxidant, and Toxicity Test with BSLT of Meistera chinensis Fruit Fraction from Southeast Sulawesi
Musdalipah, Musdalipah
Tee, Selfyana Austin
Karmilah, Karmilah
Sahidin, Sahidin
Fristiohady, Adryan
Yodha, Agung Wibawa Mahatva
Phytochemical screening
Radical scavenging
Total flavonoid
Total phenolic
Meistera chinensis
Phytochemistry
Zingiberaceae have a large number of species and still need research to reveal their chemical content. Meistera chinensis is one of the new generations of the Zingiberaceae family, a local and widespread plant in Konawe Regency, Southeast Sulawesi. Empirically, M. chinensis is used as a flavor enhancer in food, aches, and increases body immunity. There are no reports of chemical content or its biological activity. In this study, the fruit of M. chinensis was tested for phytochemicals, antioxidants using the ABTS test, total phenolic, total flavonoid content, and toxicity test with a lethal test for brine shrimp (BSLT). Meistera chinensis was extracted with ethanol and fractionated by ethyl acetate solvent using vacuum liquid chromatography. Phytochemical screening was carried out qualitatively by using the calorimetric method. The fraction toxicity was monitored by BSLT. These fractions for the ABTS method obtained fractions 1-8 (F1-F8) and ascorbic acid were used as controls. The results showed radical scavenging activities fraction of M. chinensis fruit was a very strong activity with IC50 of 42.7±3.53 mg/L (F8). The total phenolic and flavonoid contents were 30.72±1.07 mgGAE/g and 8.02±0.48 mgQE/g, respectively. The phytochemical evaluation contains terpenoids, saponins, phenolics, steroids, alkaloids, and flavonoids. The BSLT toxicity test was found to be very toxic, with an IC50 of 5.2±0.72 mg/L. These findings indicate that the fruit of M. chinensis acts as an antioxidant and toxicity agent.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2021-02-28
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1686
10.33084/bjop.v4i1.1686
Borneo Journal of Pharmacy; Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy; 6-15
2621-4814
10.33084/bjop.v4i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1686/1598
https://journal.umpr.ac.id/index.php/bjop/article/view/1686/1671
https://journal.umpr.ac.id/index.php/bjop/article/view/1686/1670
Copyright (c) 2021 Musdalipah Musdalipah, Selfyana Austin Tee, Karmilah Karmilah, Sahidin Sahidin, Adryan Fristiohady, Agung Wibawa Mahatva Yodha
oai:journal.umpr.ac.id:article/1703
2021-05-24T14:02:35Z
bjop:Pharm-Tox
Combination of Bawang Dayak Extract and Acarbose against Male White Rat Glucose Levels
Putra, Aditya Maulana Perdana
Sari, Ratih Pratiwi
Musiam, Siska
Acarbose
Bawang dayak
Glucose levels
Pharmacology
Diabetes is a chronic metabolic disease with signs of increased blood glucose levels. Type 2 diabetes is common diabetes in adults. Bawang dayak is one of the plants believed to have the efficacy of curing various types of diseases. The purpose of this study was to find out the comparison of hypoglycemic effects between combinations of bawang dayak extract and acarbose with single acarbose. This study was an experimental study using 32 white mice divided into two groups. Group one was given a combination of bawang dayak at a dose of 100 mg/kg BW and acarbose at a dose of 40 mg/100 g BW, while group two was given acarbose at a dose of 40 mg/100 g BW. Treatment is administered after the test animal is induced with dexamethasone at a 1 mg/kg BW dose dissolved in NaCl 0.9% subcutaneously for 12 days. Measurement of glucose levels was carried out using a glucometer. Data retrieval was carried out every three days for 15 days after previously fulfilled for +10 hours. Blood glucose level data were analyzed with the General Linear Model test. The combination of bawang dayak-acarbose onion extract had a greater decrease in blood glucose levels than single acarbose. Average reduction in blood glucose levels for D+3; D+6; D+9; D+12; and D+15 was 187.31; 168.56; 140.81; 119.81; and 102.56 mg/dl, respectively. The General Linear Model test results showed a p <0.05 value that significantly impacted blood glucose levels between groups.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2021-05-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1703
10.33084/bjop.v4i2.1703
Borneo Journal of Pharmacy; Vol. 4 No. 2 (2021): Borneo Journal of Pharmacy; 84-90
2621-4814
10.33084/bjop.v4i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1703/1727
https://journal.umpr.ac.id/index.php/bjop/article/view/1703/1764
https://journal.umpr.ac.id/index.php/bjop/article/view/1703/1743
Copyright (c) 2021 Aditya Maulana Perdana Putra, Ratih Pratiwi Sari, Siska Musiam
oai:journal.umpr.ac.id:article/1782
2021-05-24T14:02:32Z
bjop:Pharm-Tox
In Vitro Determination of Sun Protection Factor of Water Extract of Aerodramus fuciphagus from Central Kalimantan
Sandi, Dita Ayulia Dwi
Susiani, Eka Fitri
Adnyana, I Ketut
Wikaningtyas, Pratiwi
Sunscreen
Edible-nest swiftlet's Nest
Erythema transmission
Sun Protection Factor
Pigmentation transmission
Aerodramus fuciphagus
Pharmacology
Sunscreen is a cosmetic substance that has the ability to reflect or absorb sunlight actively. It can prevent skin irritation due to UV rays. One of the natural ingredients with a sunscreen effect is the Edible-nest swiftlet's (Aerodramus fuciphagus) nest (ESN). This study aimed to determine the value of the sun protective factor (SPF) of the ESN water extract. The ESN water extract solution with variation concentration, this is 2000, 2500, 5000, 6000, and 7000 ppm, were measured by spectrophotometric UV-Vis at wavelength 290-375 nm with 5 nm intervals to determine the value of SPF, percentage of erythema transmission (%Te), and percentage of pigmentation transmission (%Tp) of ESN water extract. The result showed that the ESN water extract's SPF values at the concentration 2000, 2500, 5000, 6000, and 7000 ppm were 7.80; 9.68; 18.75; 20.58; and 22.24. The value of %Te of each concentration were 15.60±0.19; 10.03±0.42; 1.24±0.04; 0.81±0.01 and 0.56±0.01. While the value of %Tp of each concentration was showed the sunblock category. In conclusion, the ESN water extract from Central Kalimantan at the concentration of 6000 ppm has potential in ultraviolet protection against the skin in the ultra category with sunblock category mechanism. Further, it can be developed into sunscreen cosmetics from natural ingredients.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2021-05-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1782
10.33084/bjop.v4i2.1782
Borneo Journal of Pharmacy; Vol. 4 No. 2 (2021): Borneo Journal of Pharmacy; 78-83
2621-4814
10.33084/bjop.v4i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1782/1717
https://journal.umpr.ac.id/index.php/bjop/article/view/1782/1763
https://journal.umpr.ac.id/index.php/bjop/article/view/1782/1742
Copyright (c) 2021 Dita Ayulia Dwi Sandi, Eka Fitri Susiani, I Ketut Adnyana, Pratiwi Wikaningtyas
oai:journal.umpr.ac.id:article/1817
2021-05-20T02:39:24Z
bjop:Nat-Pro-Dev
Formulation, Organoleptic Evaluation, and Acceptability of Various Teas from Underutilized Nutritious Herbs Compared with Marketed Chinese and Yellow Lipton Tea
Ehoche, Elijah Edache
Patel, Parth
Madu, Chijioke
Adejoh, Johnson
Antioxidants
Herb
Nutrients
Tea
Sensory evaluation
Natural product
Herbal teas are nutrient, antioxidant, and hydration-rich brews made from herbs and spices and taken for various purposes. The objective of this study was to formulate tea from clove (Syzygium aromaticum), leaves of lemongrass (Cymbopogon citratus), guava (Psidium guajava), and moringa (Moringa oleifera), as well as compared with Chinese and yellow Lipton Tea. The samples were analyzed for comparative sensory analysis using the 7 points hedonic scale. The sensory evaluation result demonstrated that the color of the clove tea sample (5.87) was most acceptable by participants, while the lemongrass tea (4.46) sample was least acceptable amongst all the tea samples. The clove remained the most accepted tea for aroma (6.07), taste (5.92), texture (5.76), general appearance (5.74), and general acceptability (5.93), in 7 points hedonic scale. However, all tea samples were had significant acceptable scores above average (p <0.05). Owing to the above results, these herbs can be successfully used to produce tea of relatively good quality to encourage herbs' local consumption and stay healthy.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2021-02-28
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1817
10.33084/bjop.v4i1.1817
Borneo Journal of Pharmacy; Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy; 51-56
2621-4814
10.33084/bjop.v4i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1817/1604
https://journal.umpr.ac.id/index.php/bjop/article/view/1817/1682
https://journal.umpr.ac.id/index.php/bjop/article/view/1817/1683
Copyright (c) 2021 Elijah Edache Ehoche, Parth Patel, Chijioke Madu, Johnson Adejoh
oai:journal.umpr.ac.id:article/1826
2021-05-24T14:02:30Z
bjop:Pharmaceut
Identification of the Glimepiride and Metformin Hydrochloride Physical Interaction in Binary Systems
Darusman, Fitrianti
Fakih, Taufik Muhammad
Nurfarida, Gina Fuji
Glimepiride
Metformin HCl
Physical Interaction
Phase Diagram
Computational Approach
Solid State Interactions
Glimepiride is often combined with metformin HCl as an oral antidiabetic in type II diabetes mellitus, which provides a complementary and synergistic effect with multiple targets for insulin secretion. Glimepiride includes class II of BCS, which solubility practically insoluble in water but high permeability, which will impact the drug's small bioavailability. In contrast, metformin HCl includes class III of BCS, which has a high solubility in water, but low permeability is absorbed approximately 50-60% in the digestive tract given orally. The co-crystallization method can be used to improve the glimepiride solubility properties and the permeability properties of metformin HCl by interrupting glimepiride with metformin HCl physically. This study aims to identify the physical interactions between glimepiride and metformin HCL using a thermal analysis of Differential Scanning Calorimetry (DSC) and then confirmed by a computational approach. Identifying the physical interactions between glimepiride and metformin HCL was carried out by plotting the melting points generated from the endothermic peaks of the DSC thermogram at various compositions versus the mole ratios of the two were further confirmed by the computational approach using PatchDock. The results of the phase diagram analysis of the binary system between glimepiride and metformin HCl show a congruent pattern, which indicates the formation of co-crystal or molecular compounds at a 1 : 1 mole ratio at 228°C. Computational approach results showed that the interaction between glimepiride and metformin HCl did not form new compounds but heterosinton formation that was stable in molecular dynamics simulations.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2021-05-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1826
10.33084/bjop.v4i2.1826
Borneo Journal of Pharmacy; Vol. 4 No. 2 (2021): Borneo Journal of Pharmacy; 110-116
2621-4814
10.33084/bjop.v4i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1826/1734
https://journal.umpr.ac.id/index.php/bjop/article/view/1826/1767
https://journal.umpr.ac.id/index.php/bjop/article/view/1826/1752
Copyright (c) 2021 Fitrianti Darusman, Taufik Muhammad Fakih, Gina Fuji Nurfarida
oai:journal.umpr.ac.id:article/1830
2023-05-25T03:53:13Z
bjop:Pharm-Phyto
Column Chromatography Fractionation and Antioxidant Activity of Passiflora foetida Leaves
Triadisti, Nita
Zamzani, Irfan
Antioxidant
Passiflora foetida
Fractionation
DPPH
FRAP
Pharmacognosy
Available synthetic antioxidants have been reported to have mutagenic and toxic effects. On the other hand, natural antioxidants show their superiority as they are not or less toxic. Passiflora foetida has the potential as an antioxidant, but the investigation of the antioxidant activity of the P. foetida chromatography column fraction has not been reported. This studied aims to investigate the antioxidant activity of the column chromatographic fractions of P. foetida leaves. An antioxidant assay using the DPPH and FRAP methods. The extraction was carried out by graded maceration, then fractionation using column chromatography. The antioxidant activity test was carried out using the DPPH and FRAP methods. Thin Layer Chromatography analysis was performed to determine the chromatogram pattern. The EC50 using DPPH method from n-hexane extract: 129.035 µg/mL, ethyl acetate extract: 206.398 µg/mL, methanol extract: 97.453 µg/mL, while the EC50 using FRAP method from n-hexane extract: 67.851 µg/mL, ethyl acetate extract : 68.981 µg/mL, and methanol extract: 58.787 µg/mL. Column chromatography fractions have antioxidant activity, with FMetPF6 as the fraction with the best activity, with percent inhibition 41.85±1.96 at concentration 25 µg/mL (DPPH), and with percent antioxidant activity 26.03±0.84 at concentration 9 µg/mL (FRAP). Passiflora foetida leaves have great potential as an antioxidant; both the extract and its fractions have antioxidant activity. The FMetPF6 has the best activity compare to other extracts and fractions. Further analysis to determine the various compounds in FMetPF6 using LC-MS/MS will facilitate the active compound's isolation.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2023-02-28
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1830
10.33084/bjop.v6i1.1830
Borneo Journal of Pharmacy; Vol. 6 No. 1 (2023): Borneo Journal of Pharmacy; 22-30
2621-4814
10.33084/bjop.v6i1
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1830/3105
Copyright (c) 2023 Nita Triadisti, Irfan Zamzani
https://creativecommons.org/licenses/by-sa/4.0
oai:journal.umpr.ac.id:article/1838
2021-09-15T08:41:34Z
bjop:Microbiology
Detection of Salmonella typhimurium ATCC 14028 in Powder Prepared Traditional Medicines Using Real-Time PCR
Sophian, Alfi
Purwaningsih, Ratna
Muindar, Muindar
Igirisa, Eka Putri Juniarti
Amirullah, Muhammad Luthfi
DNA
Salmonella typhimurium
Traditional medicine
Microbiology pharmacy
The detection of Salmonella typhimurium ATCC 14028 using real-time PCR on powdered traditional medicinal products was carried out in the microbiology and molecular biology testing laboratory of the Food and Drug Administration in Gorontalo. This research aims to provide a reference for alternative testing methods in testing the products of traditional powder preparations on the market. The sample consisted of 10 traditional powder preparations spiked with positive control of S. typhimurium ATCC 14028 phase 2. The method used in the study was real-time PCR analysis using the SYBR® Green method, while DNA isolation using the direct PCR method. Data analysis was performed by analyzing the sample's melting temperature (Tm) curve and comparing it with positive control. The results showed that S. typhimurium ATCC 14028 was detected in samples at an average Tm value of 84.18°C, with ranges of 84.0-84.5°C. For positive control, the Tm value was at 85.2°C, while for the negative control, the Tm value was not detected. Based on these data, it can be concluded that S. typhimurium ATCC 14028 in traditional medicine products powder preparations can be detected using real-time PCR.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2021-08-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1838
10.33084/bjop.v4i3.1838
Borneo Journal of Pharmacy; Vol. 4 No. 3 (2021): Borneo Journal of Pharmacy; 178-183
2621-4814
10.33084/bjop.v4i3
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1838/1938
https://journal.umpr.ac.id/index.php/bjop/article/view/1838/2051
https://journal.umpr.ac.id/index.php/bjop/article/view/1838/1939
Copyright (c) 2021 Alfi Sophian, Ratna Purwaningsih, Muindar Muindar, Eka Putri Juniarti Igirisa, Muhammad Luthfi Amirullah
oai:journal.umpr.ac.id:article/1854
2021-05-24T14:02:27Z
bjop:Pharmaceut
Formulation and Evaluation of Sustained Release Matrix Tablets of Aceclofenac
Singh, Priyanka
Shrivastava, Amit Kumar
Kumar, Sachin
Dwivedi, Manish Dhar
Aceclofenac
Sustained release matrix tablet
Controlled release tablet
Pharmaceutics
This study aimed to improve the dissolution rate of aceclofenac and release the drug in a controlled manner over a period of 24 hours. Matrix tablets were prepared by direct compression method, using hydrophilic polymers (HPMC/guar gum). Matrix tablets were prepared by wet granulation method using different hydrophilic polymers (HPMC/guar gum). Tablets were evaluated for in vitro drug release profile in phosphate buffer with pH 6.8 (without enzymes). The thickness and hardness of prepared tablets were 3.23 ± 0.035 to 3.28 ± 0.008 mm and 3.26 ± 0.115 to 3.60 ± 0.200 kg/cm2, respectively. The friability was within the acceptable limits of pharmacopoeial specifications (0.31 to 0.71%), which indicates the good mechanical strength of the tablets. Drug release was retarded with an increase in polymer concentration due to the gelling property of polymers. The in vitro drug release from the proposed system was best explained by Higuchi’s model, indicating that drug release from tablets displayed a diffusion-controlled mechanism. The results clearly indicate that guar gum could be a potential hydrophilic carrier in developing oral controlled drug delivery systems. Based on the study results, formulations F8 was selected as the best formulation.
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya
2021-05-30
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
text
application/pdf
application/xml
application/pdf
https://journal.umpr.ac.id/index.php/bjop/article/view/1854
10.33084/bjop.v4i2.1854
Borneo Journal of Pharmacy; Vol. 4 No. 2 (2021): Borneo Journal of Pharmacy; 99-109
2621-4814
10.33084/bjop.v4i2
eng
https://journal.umpr.ac.id/index.php/bjop/article/view/1854/1729
https://journal.umpr.ac.id/index.php/bjop/article/view/1854/1766
https://journal.umpr.ac.id/index.php/bjop/article/view/1854/1751
Copyright (c) 2021 Priyanka Singh, Amit Kumar Shrivastava, Sachin Kumar, Manish Dhar Dwivedi
c07173334dffe446afdb1055082af077