Kandungan Antioksidan Daun Mahang Damar (Macaranga triloba (Bl.) Muell Arg.)
In the year 2015, the plants that initially grow a lot of wild is increasing in popularity because many contested by the citizens. The reason is because the plant has an economic value. Based on the literature review it is known that apigenin, a flavonoid compound has been isolated from the ethyl acetate fraction of methanolic extract of Macaranga gigantia leaf. Compounds that have potential as antioxidants are generally compounds of flavonoids, phenolics, and alkaloids. Flavonoid and polyphenolic compounds are antioxidant, antidiabetic, anticancer, antiseptic, and anti-inflammatory, while alkaloids have antineoplastic properties that also inhibit the growth of cancer cells. Phenol content, antioxidant activity and antibacterial activity were also found in Macaranga gigantea, M. hosei, M. hypoleuca, M. kingii, M. pruinosa and M. triloba (Lim et.al., 2014). This leads to the notion that mahang leaves were obtained and collected from the Central Kalimantan region where this study carried out also contained similar content and activity. Determination of the value of antioxidant activity in this study using DPPH method performed on n-hexane extract ofmahang leaf obtained by maceration. N-hexane extract of mahang leaf have antioxidant activity, this can be seen from the preliminary TLC test results where the spots produced when sprayed with DPPH fluoresce when viewed at 366 nm uv. The average value of IC50n-hexane extract of mahang leaves was 141.3 ppm.
Departemen Kesehatan Republik Indonesia.(1995). Materia Medika IndonesiaJilid VI. Jakarta: Departemen Kesehatan Republik Indonesia.
Isnindar., Setyowat, E.P., dan Wahyuono, S. (2011). Aktivitas Antioksidan Daun Kesemek (Diospyros kaki L.F) Dengan Metode DPPH (2,2-DifenilPikrilhidrazin). Majalah Obat tradisional.
Kandaswami, C dan Middleton, E (1997), Flavonoids as an antioxidant, In F. Shahidi (Ed). Natural Antioxidant Chemistry, Health Effects, and Applications. Champaign Illinois: AOCS Press.
Lim T.Y., Lim Y.Y., dan Yule C.M. 2014.Bioactivity of leaves of Macaranga species in tropical peat swamp and non-peat swamp environments. Journal of Tropical Forest Science 26(1): 134–141.
Megawati, Saepudin E., Hanafi M., Darmawan A., dan Dewi N. L.P. 2015. Identification and Bioactivity Studies of Flavonoid Compounds from Macaranga hispida (Blume) Mull.Arg. Makara J. Sci. 19( 3):96-100 doi: 10.7454/mss.v19i3.4848
Molyneux, P. (2004). The Use of The Stable Free Radical Diphenyl Picrylhydrazil (DPPH) for Estimating Antioxidant Activity. Songklankarin J. Sci. Technol., 26 (2), 211-219.
Wagner, H., Blandt, S., dan Zgalnski. (1984). Plant Drug Analysis. New York: Springer-Verlag, 7-304.
Winarsi, H. (2007). Antioksidan Alami dan Radikal Bebas. Yogyakarta: Kanisius.
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