Survival Analisis Suhu Tubuh pada Pasien Diare yang Diberikan Vitamin D

Survival Analysis of Body Temperature in Patient Diarrhea Which is Given Vitamin D

  • Sutrimo Usali R Universitas Ahmad Dahlan
  • Endang Darmawan Universitas Ahmad Dahlan
  • Nurcholid Umam Kurniawan Universitas Ahmad Dahlan
Keywords: Diarrhea, Vitamin D, Fever


Diarrhea is a disease that attacks the digestive system, and most caused by microorganisms (bacteria and viruses) Diarrhea is still the second largest cause of death in the world after pneumonia and is still a public health problem in developing countries like Indonesia. Vitamin D is a potential mediator in regulating the immune system to become the body's defense against infection. This study aims to determine the effectiveness of vitamin D based on body temperature parameters. The study was conducted using a double-blind randomized clinical trial experimental research design, in which researchers conducted clinical trials in the control group (placebo) and there was a comparison group (vitamin D adjuvant). Vitamin D provides a better chance of survival as well as a better chance of a decrease in body temperature compared to patients who do not get vitamin D therapy as an adjuvant (additional). Significant results occurred on days 3, 5 and 6.


Download data is not yet available.


Radlovic, N., Lekovic, Z., Vuletic, B., Radlovic, V., & Simic, D. (2015). Acute diarrhea in children. Srpski Arhiv Za Celokupno Lekarstvo, 143(11–12), 755–762.
Kemenkes RI. (2011). Buletin Jendela Data dan Informasi Kesehatan Situasi Diare di Indonesia. Jurnal Buletin Jendela Data & Informasi Kesehatan, 2, 1–44.
UNICEF. (2018). Estimates of child cause of death, diarrhoea 2018.
Dairo, M. D., Ibrahim, T. F., & Salawu, A. T. (2017). Prevalence and determinants of diarrhoea among infants in selected primary health centres in kaduna north local government area, nigeria. Pan African Medical Journal, 28, 1–9.
Bonkoungou, I. J. O., Haukka, K., Osterblad, M., Hakanen, A. J., Traore, A. S., Barro, N., & Siitonen, A. (2013). Bacterial and viral etiology of childhood diarrhea in Ouagadougou, Burkina Faso. BMC Pediatrics, 13(1).
Guarino, A., Ashkenazi, S., Gendrel, D., Lo Vecchio, A., Shamir, R., & Szajewska, H. (2014). ESPGHAN/ESPID Evidence-Based Guidelines for the Management of Acute Gastroenteritis in Children in Europe: Update 2014. J Pediatr Gastroenterol Nutr, 59(1), 132–152.
Bruzzese, E., Giannattasio, A., & Guarino, A. (2018). Antibiotic treatment of acute gastroenteritis in children. F1000 Research, 7, 193.
Lukman Zulkifli Amin. (2015). Tatalaksana Diare Akut. Cdk-230, 42(7), 504–508.
Sudiono, J. 2015. Sistem Kekebalan Tubuh. Penerbit Buku Kedokteran EGC
Bikle, D. D. (2014). Vitamin D metabolism, mechanism of action, and clinical applications. Chemistry & Biology, 21(3), 319–329.
Pludowski, P., Holick, M. F., Pilz, S., Wagner, C. L., Hollis, B. W., Grant, W. B., Shoenfeld, Y., Lerchbaum, E., Llewellyn, J. D., Kienreich, K., Soni, M. (2013). Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality-A review of recent evidence. Autoimmunity Reviews, 12(10), 976–989.
Mermel, L. A. (2013). Infection prevention and control during prolonged human space travel. Clinical Infectious Diseases, 56(1), 123–130.
Siziya, S., Muula, A. S., & Rudatsikira, E. (2013). Correlates of diarrhoea among children below the age of 5 years in Sudan. African Health Sciences, 13(2), 376–383.
Aluisio, Adam R., Maroof, Z., Chandramohan, D., Bruce, J., Zulf Mughal, M., Bhutta, Z., Walraven, Gijs., Masher, Mohammad I., Ensink, Jeroen H.J., Manaseki-Holland, S. (2013). Vitamin D3 supplementation and childhood diarrhea: A randomized controlled trial. Pediatrics, 132(4).
S, Rajshekhar. C., Vanaki, R., Badakali, A. V., Pol, Ramesh. R., & C, Yalemali. B. (2015). Efficacy of vitamin D supplementation in the treatment of severe pneumonia in children aged less than five years. International Journal of Contemporary Pediatrics, 3(1), 96–99.
How to Cite
Usali R, S., Darmawan, E., & Kurniawan, N. U. (2020). Survival Analisis Suhu Tubuh pada Pasien Diare yang Diberikan Vitamin D. Jurnal Surya Medika (JSM), 5(2), 139-145.