Efek Konsumsi Minuman Beralkohol terhadap Kadar Kreatinin

Effects of Consumption of Alcoholic Beverages on Creatinine Levels

Keywords: Alcohol drinker, Creatinine, Kidney Function

Abstract

Long-term and excessive alcohol consumption is a risk factor for chronic diseases such as impaired kidney function. Acute and chronic alcohol consumption can increase blood pressure which is a risk factor for kidney damage. Oxidative stress play a role in the kidney damage that induced by ethanol. In this study aims to the description of creatinine levels in moderate and heavy alcohol drinkers in Jalan Mendawai Kota Palangka Raya. This study used the descriptive method to describe the effect of consuming alcohol on kidney function using creatinine level parameters. Total sample used is 20 people with snowballs Sampling technique. The inclusion criteria such as male, age over 20 years old, consumed alcohol more than 5 years, consumed alcohol every day. Creatinine examination was done by Jaffe Reaction method using Photometer 5010 V5 +. The results showed that 15 people (75%) had high creatinine levels and 5 people (25%) had normal creatinine levels.

Downloads

Download data is not yet available.

Author Biography

Dwi Purbayanti, Universitas Muhammadiyah Palangkaraya

Lecturer of Medical Laboratory Technology

Universitas Muhammadiyah Palangkaraya

References

Park H, Kim K. Association of alcohol consumption with lipid profile in hypertensive men. Alcohol Alcohol. 2012;47(3):282-287. doi:10.1093/alcalc/ags019.
Schaeffner E, Ritz E. Alcohol and kidney damage: A Janus-faced relationship. In: Kidney International. Vol 81. Elsevier Masson SAS; 2012:816-818. doi:10.1038/ki.2012.14.
Epstein M. Alcohol’ s Impact on Kidney Function. Alcohol Health Res World. 1997;21(1):84-93.
Islam M, Islam M, Hossain M, Wares M. Kidney histotexure and serum creatinine level in response to concurrent administration of alcohol and coffee in mice. Bangladesh Vet. 2016;32(2):42. doi:10.3329/bvet.v32i2.30609.
Savdie E, Grosslight GM, Adena MA. Relation of alcohol and cigarette consumption to blood pressure and serum creatinine levels. J Chronic Dis. 1984;37(8):617-623.
Kim H-N, Kim S, Song S-W. Is Alcohol Drinking Associated with Renal Impairment in the General Population of South Korea? Kidney Blood Press Res. 2014;39(1):40-49. doi:10.1159/000355775.
Hsu Y-H, Pai H, Chang Y, Liu W, Hsu C. Alcohol consumption is inversely associated with stage 3 chronic kidney disease in middle-aged Taiwanese men. BMC Nephrol. 2013;14:254. doi:10.1186/1471-2369-14-254.
Cheungpasitporn W, Thongprayoon C, Kittanamongkolchai W, et al. High alcohol consumption and the risk of renal damage: A systematic review and meta-analysis. QJM. 2015;108(7):539-548. doi:10.1093/qjmed/hcu247.
Ayu Kasmita Dewi, Ni Made Rai Suarni NMS. GAMBARAN MIKROSKOPIS GINJAL TIKUS PUTIH (Rattus sp) JANTAN DEWASA SETELAH PEMBERIAN ETANOL KRONIS. J Biol Udayana. 2012;2(2):33-36.
Das SK, Varadhan S, Dhanya L, Mukherjee S, Vasudevan DM. Effects of Chronic Ethanol Exposure on Renal Function Tests and Oxidative Stress in Kidney. Indian J Clin Biochem. 2008;23(4):341-344. http://medind.nic.in/iaf/t08/i4/iaft08i4p341.pdf.
White SL, Polkinghorne KR, Cass A, Shaw JE, Atkins RC, Chadban SJ. Alcohol consumption and 5-year onset of chronic kidney disease: The AusDiab study. Nephrol Dial Transplant. 2009;24(8):2464-2472. doi:10.1093/ndt/gfp114.
12. Sandoval C, Vásquez B, Mandarim-de-Lacerda C, del Sol M. Ethanol intake and toxicity: In search of new treatments. Int J Morphol. 2017;35(3):942-949. doi:10.4067/S0717-95022017000300024.
Harris PS, Roy SR, Coughlan C, et al. Chronic ethanol consumption induces mitochondrial protein acetylation and oxidative stress in the kidney. Redox Biol. 2015;6:33-40. doi:10.1016/j.redox.2015.06.021.
Perrone D, Levey S. Serum Creatinine as an index of renal function : New insights into old concepts. Clin Chem. 1992;38(10):1933-1953.
Li X-M, Ma Y-T, Xie X, Yang Y-N, Li XM, Zheng Y-Y. Relationship between serum creatinine and obesity in children in Xinjiang, China. Genet Mol Res. 2014;13(2):2409-2416. doi:10.4238/2014.April.3.13.
Varga Z V, Matyas C, Paloczi J, Pacher P. Alcohol Misuse and Kidney Injury: Epidemiological Evidence and Potential Mechanisms. Alcohol Res Curr Rev. 2017;38(2):283-288.
Published
2018-08-01
How to Cite
Purbayanti, D. (2018). Efek Konsumsi Minuman Beralkohol terhadap Kadar Kreatinin. Jurnal Surya Medika (JSM), 4(1), 44-50. https://doi.org/10.33084/jsm.v4i1.349

Most read articles by the same author(s)

1 2 > >>